『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
ID: Pass:

登録内容 (EID=95044)

EID=95044EID:95044, Map:0, LastModified:2018年5月23日(水) 17:08:56, Operator:[[ADMIN]], Avail:TRUE, Censor:0, Owner:[六車 直樹], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1. (英) Inoi Junya (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
2.清水 一郎
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
3. (英) Tsuji Yasuhiro (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
4.六車 直樹 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.内科系.消化器内科学]/[徳島大学.病院.診療科.内科.消化器内科])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
5.伊東 進
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) Effect of administration of ursodeoxycholic acid at bedtime on cholesterol saturation of hepatic bile in Japanese patients with gallstone  (日)    [継承]
副題 (任意):
要約 (任意): (英) The administration of a single, daily 600 mg dose of ursodeoxycholic acid (UDCA) at bedtime and 3-200 mg doses per day at mealtime was conducted for 6 patients with gallstone and choledocholithiasis who were undergoing biliary drainage for the purpose of improving jaundice. Hepatic bile was collected from a drainage tube after a lapse of time in order to compare the bile acid compositions and cholesterol saturation index (SI) in bile for the 2 protocols. A significant increase in UDCA levels in hepatic bile was observed after both UDCA administration at bedtime and mealtime, but the effect of bedtime administration was significantly greater than that of mealtime administration. Whereas levels of cholic acid and chenodeoxycholic acid (CDCA) decreased for the case of bedtime administration, this was not detected for mealtime administration, although no significant differences among the mean interval values were observed. A significant in difference decreased SI was observed during UDCA bedtime administration, but not during mealtime administration, compared to the SI before administration. This suggests a decreased cholesterol excretion into the bile. Based on these findings and from the point of view of compliance, bedtime administration of UDCA appears to be an effective method.  (日)    [継承]
キーワード (推奨): 1. (英) Adult (日) (読) [継承]
2. (英) Aged (日) (読) [継承]
3. (英) Bile (日) (読) [継承]
4. (英) Bile Acids and Salts (日) (読) [継承]
5. (英) Cholagogues and Choleretics (日) (読) [継承]
6. (英) Cholelithiasis (日) (読) [継承]
7. (英) Cholesterol (日) (読) [継承]
8. (英) Drug Administration Schedule (日) (読) [継承]
9. (英) Eating (日) (読) [継承]
10. (英) Female (日) (読) [継承]
11. (英) Gallstones (日) (読) [継承]
12. (英) Humans (日) (読) [継承]
13. (英) Male (日) (読) [継承]
14. (英) Middle Aged (日) (読) [継承]
15. (英) Ursodeoxycholic Acid (日) (読) [継承]
発行所 (推奨):
誌名 (必須): The Journal of Medical Investigation : JMI ([徳島大学.医学部])
(pISSN: 1343-1420, eISSN: 1349-6867)

ISSN (任意): 1343-1420
ISSN: 1343-1420 (pISSN: 1343-1420, eISSN: 1349-6867)
Title: The journal of medical investigation : JMI
Title(ISO): J Med Invest
Supplier: 徳島大学
Publisher: Tokushima Daigaku Igakubu
 (NLM Catalog  (Webcat Plus  (医中誌Web  (J-STAGE  (Scopus  (CrossRef (Scopus information is found. [need login])
[継承]
[継承]
(必須): 45 [継承]
(必須): 1,4 [継承]
(必須): 115 122 [継承]
都市 (任意):
年月日 (必須): 西暦 1998年 2月 初日 (平成 10年 2月 初日) [継承]
URL (任意):
DOI (任意):
PMID (任意): 9864972    (→Scopusで検索) [継承]
NAID (任意):
WOS (任意):
Scopus (任意):
機関リポジトリ : 111632 [継承]
評価値 (任意):
被引用数 (任意):
指導教員 (推奨):
備考 (任意): 1.(英) Article.PublicationTypeList.PublicationType: Clinical Trial  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Comparative Study  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]

標準的な表示

和文冊子 ● Junya Inoi, Ichiro Shimizu, Yasuhiro Tsuji, Naoki Muguruma and Susumu Ito : Effect of administration of ursodeoxycholic acid at bedtime on cholesterol saturation of hepatic bile in Japanese patients with gallstone, The Journal of Medical Investigation : JMI, Vol.45, No.1,4, 115-122, 1998.
欧文冊子 ● Junya Inoi, Ichiro Shimizu, Yasuhiro Tsuji, Naoki Muguruma and Susumu Ito : Effect of administration of ursodeoxycholic acid at bedtime on cholesterol saturation of hepatic bile in Japanese patients with gallstone, The Journal of Medical Investigation : JMI, Vol.45, No.1,4, 115-122, 1998.

関連情報

Number of session users = 0, LA = 1.12, Max(EID) = 372484, Max(EOID) = 996185.