| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○学究種別 (推奨): |
| ○組織 (推奨): |
| ○著者 (必須): | 1. | (英) Wigianto Putra Yoshi Adityakrisna (日) (読)
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| 2. | 石田 雄一 ([徳島大学.病院.診療科.歯科.そしゃく科(第一補綴科)])
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| 3. | 岩脇 有軌 ([徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.臨床歯学系.口腔顎顔面補綴学])
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| 4. | 後藤 崇晴 ([徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.臨床歯学系.口腔顎顔面補綴学])
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| 5. | 渡邉 恵 ([徳島大学.病院.診療科.歯科.そしゃく科(第一補綴科)])
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| 6. | 関根 一光 ([徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.基礎歯学系.生体材料工学])
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| 7. | 浜田 賢一 ([徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.基礎歯学系.生体材料工学])
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| 8. | 村上 圭史
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| 9. | 藤猪 英樹
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| 10. | 市川 哲雄
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| ○題名 (必須): | □ | (英) 2-methacryloyloxyethyl phosphorylcholine polymer treatment prevents Candida albicans biofilm formation on acrylic resin (日)
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| ○要約 (任意): | □ | (英) We aimed to evaluate the effectiveness of photoreactive 2-methacryloyloxyethyl phosphorylcholine (MPC) in inhibiting Candida albicans biofilm formation on polymethyl methacrylate (PMMA) and assess its mechanism and need for re-application by evaluating its interaction with salivary mucin and durability during temperature changes. PMMA discs were used as specimens. The MPC coating was applied using the spray and cure technique for the treatment groups, whereas no coating was applied to the control. The MPC treatment (MT) groups were further differentiated based on the number of thermal cycles involved (0, 1000, 2500, and 5000). The optical density was measured to assess mucin adsorption (MA). Contact angle (CA) was calculated to evaluate surface hydrophilicity. The presence of MPC components on the PMMA surface was assessed using X-ray photoelectron spectroscopy (XPS). C. albicans biofilms were evaluated qualitatively (scanning electron microscope images) and quantitatively (colony-forming units (CFUs)). Statistical analysis was conducted using two-way analysis of variance and Tukey's multiple comparison test. MA rate and CA increased significantly in the MT groups, which exhibited significantly fewer CFUs and thinner biofilms than those of the control group. Based on the XPS, MA, and CFU evaluations, the durability and efficacy of the MPC coating were considered stable up to 2500 thermal cycles. Additionally, a significant interaction was observed between mucin concentration and MPC efficacy. The photoreactive MPC coating, which was resistant to temperature changes for approximately 3 months, effectively prevented C. albicans biofilm formation by modifying surface hydrophilicity and increasing mucin adsorption. (日)
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| ○キーワード (推奨): | 1. | (英) Candida albicans (日) (読)
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| 2. | (英) Acrylic Resins (日) (読)
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| 3. | (英) Polymers (日) (読)
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| 4. | (英) Polymethyl Methacrylate (日) (読)
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| 5. | (英) Surface Properties (日) (読)
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| 6. | (英) Biofilms (日) (読)
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| 7. | (英) Mucins (日) (読)
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| ○発行所 (推奨): |
| ○誌名 (必須): | □ | Journal of Prosthodontic Research ([日本補綴歯科学会])
(pISSN: 1883-1958, eISSN: 2212-4632)
| ○ISSN (任意): | □ | 2212-4632
ISSN: 1883-1958
(pISSN: 1883-1958, eISSN: 2212-4632) Title: Journal of prosthodontic researchTitle(ISO): J Prosthodont ResSupplier: 公益社団法人 日本補綴歯科学会Publisher: Japan Prosthodontic Society (NLM Catalog)
(医中誌Web)
(J-STAGE)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
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| ○巻 (必須): | □ | 67
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| ○号 (必須): | □ | 3
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| ○頁 (必須): | □ | 384 391
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2022年 10月 27日 (令和 4年 10月 27日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.2186/jpr.JPR_D_22_00102 (→Scopusで検索)
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| ○PMID (任意): | □ | 36288959 (→Scopusで検索)
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| ○CRID (任意): |
| ○WOS (任意): |
| ○Scopus (任意): | □ | 2-s2.0-85166383313
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| ○備考 (任意): | 1. | (英) Article.ELocationID: 10.2186/jpr.JPR_D_22_00102 (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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| 3. | (英) KeywordList.Keyword: 2-methacryloyloxyethyl phosphorylcholine (日)
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| 4. | (英) KeywordList.Keyword: Candida albicans (日)
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| 5. | (英) KeywordList.Keyword: Denture plaque (日)
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| 6. | (英) KeywordList.Keyword: PMMA (日)
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