| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○カテゴリ (推奨): |
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| ○組織 (推奨): |
| ○著者 (必須): | 1. | (英) Zhang Weici (日) (読)
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| 2. | (英) Shao Tihong (日) (読)
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| 3. | (英) Leung Patrick S C (日) (読)
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| 4. | 常山 幸一 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.病理系.疾患病理学])
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| 5. | (英) Heuer Luke (日) (読)
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| 6. | (英) Young Howard A (日) (読)
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| 7. | (英) Ridgway William M (日) (読)
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| 8. | (英) Gershwin M Eric (日) (読)
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| ○題名 (必須): | □ | (英) Dual B-cell targeting therapy ameliorates autoimmune cholangitis. (日)
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| ○要約 (任意): | □ | (英) B cell subset which was sensitive to dual B-cell targeting therapy and depletion of this unique population was associated with reduced portal infiltration and bile duct damage. Taken together, our data indicate that dual B cell targeting therapy with anti-BAFF and anti-CD20 not only led to the efficient depletion of B cells both in the peripheral blood and tissues, but also led to significant clinical improvement. These findings highlight the potential application of combination of anti-BAFF and anti-CD20 in treating patients with PBC. However, additional studies in other animal models of PBC should be undertaken before considering human trials in those PBC patients who have incomplete responses to conventional therapy. (日)
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| ○キーワード (推奨): |
| ○発行所 (推奨): |
| ○誌名 (必須): | □ | Journal of Autoimmunity ([Elsevier])
(pISSN: 0896-8411, eISSN: 1095-9157)
| ○ISSN (任意): | □ | 1095-9157
ISSN: 0896-8411
(pISSN: 0896-8411, eISSN: 1095-9157) Title: Journal of autoimmunityTitle(ISO): J AutoimmunPublisher: Academic Press (NLM Catalog)
(Scopus)
(CrossRef)
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| ○巻 (必須): | □ | 132
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| ○号 (必須): |
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| ○年月日 (必須): | □ | 西暦 2022年 8月 24日 (令和 4年 8月 24日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1016/j.jaut.2022.102897 (→Scopusで検索)
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| ○PMID (任意): | □ | 36029718 (→Scopusで検索)
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| ○備考 (任意): | 1. | (英) PublicationType: Journal Article (日)
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