| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○招待 (推奨): |
| ○審査 (推奨): | □ | Peer Review
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| ○カテゴリ (推奨): | □ | 研究
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| ○共著種別 (推奨): | □ | 国内共著 (徳島大学内研究者と国内(学外)研究者との共同研究 (国外研究者を含まない))
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| ○学究種別 (推奨): |
| ○組織 (推奨): | 1. | 徳島大学.ポストLEDフォトニクス研究所 (2019年3月1日〜)
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| 2. | 徳島大学.先端技術科学教育部.知的力学システム工学専攻 (2006年4月1日〜)
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| ○著者 (必須): | 1. | 水野 孝彦
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| 2. | 長谷 栄治 ([徳島大学.ポストLEDフォトニクス研究所])
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| 3. | 南川 丈夫
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| 4. | 時実 悠 ([徳島大学.ポストLEDフォトニクス研究所])
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| 5. | (英) Oe Ryo (日) 麻植 凌 (読) おえ りょう
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| ○学籍番号 (推奨): | □ | ****
| [ユーザ] |
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| 6. | (英) Koresawa Hidenori (日) 是澤 秀紀 (読) これさわ ひでのり
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| ○学籍番号 (推奨): | □ | ****
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| 7. | 山本 裕紹
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| 8. | 安井 武史 ([徳島大学.ポストLEDフォトニクス研究所]/[徳島大学.理工学部.理工学科.機械科学コース.生産工学講座])
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| ○学籍番号 (推奨): |
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| ○題名 (必須): | □ | (英) Full-field fluorescence lifetime dual-comb microscopy using spectral mapping and frequency multiplexing of dual-comb optical beats (日)
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| ○副題 (任意): |
| ○要約 (任意): | □ | (英) Fluorescence lifetime imaging microscopy (FLIM) is a powerful tool for quantitative fluorescence imaging because fluorescence lifetime is independent of concentration of fluorescent molecules or excitation/detection efficiency and is robust to photobleaching. However, since most FLIMs are based on point-to-point measurements, mechanical scanning of a focal spot is needed for forming an image, which hampers rapid imaging. Here, we demonstrate scan-less full-field FLIM based on a one-to-one correspondence between two-dimensional (2D) image pixels and frequency-multiplexed radio frequency (RF) signals. A vast number of dual-comb optical beats between dual optical frequency combs are effectively adopted for 2D spectral mapping and high-density frequency multiplexing in the RF region. Bimodal images of fluorescence amplitude and lifetime are obtained with high quantitativeness from amplitude and phase spectra of fluorescence RF comb modes without the need for mechanical scanning. The parallelized FLIM will be useful for rapid quantitative fluorescence imaging in life science. (日)
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| ○キーワード (推奨): |
| ○発行所 (推奨): | □ | (英) American Association for the Advancement of Science (日) (読)
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| ○誌名 (必須): | □ | Science Advances (American Association for the Advancement of Science)
(eISSN: 2375-2548)
| ○ISSN (任意): | □ | 2375-2548
ISSN: 2375-2548
(eISSN: 2375-2548) Title: Science advancesTitle(ISO): Sci AdvPublisher: American Association for the Advancement of Science (NLM Catalog)
(Scopus)
(CrossRef)
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| ○巻 (必須): | □ | 7
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| ○号 (必須): | □ | 1
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| ○頁 (必須): | □ | eabd2102 eabd2102
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2021年 1月 1日 (令和 3年 1月 1日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1126/sciadv.abd2102 (→Scopusで検索)
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| ○PMID (任意): | □ | 33523842 (→Scopusで検索)
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| ○備考 (任意): | 1. | (英) Article.ELocationID: eabd2102 (日)
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| 2. | (英) Article.ELocationID: 10.1126/sciadv.abd2102 (日)
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| 3. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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