『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=376443EID:376443, Map:0, LastModified:2021年6月23日(水) 14:14:50, Operator:[松木 均], Avail:TRUE, Censor:0, Owner:[松木 均], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨): Peer Review [継承]
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨): 1.徳島大学.大学院生物資源産業学研究部 (2016年4月1日〜2017年3月31日) [継承]
著者 (必須): 1.後藤 優樹 ([徳島大学.大学院社会産業理工学研究部.生物資源産業学域.応用生命系.応用生物資源学分野]/[徳島大学.生物資源産業学部.生物資源産業学科.応用生命講座])
役割 (任意): (英)   (日) 記述,実験,考察   [継承]
貢献度 (任意):
学籍番号 (推奨):
[継承]
2. (英) Kazama Akira (日) (読)
役割 (任意): (英)   (日) 実験   [継承]
貢献度 (任意):
学籍番号 (推奨): **** [ユーザ]
[継承]
3. (英) Fukuhara Kensuke (日) (読)
役割 (任意): (英)   (日) 実験   [継承]
貢献度 (任意):
学籍番号 (推奨): **** [ユーザ]
[継承]
4. (英) Sato Honami (日) (読)
役割 (任意): (英)   (日) 実験   [継承]
貢献度 (任意):
学籍番号 (推奨): **** [ユーザ]
[継承]
5.玉井 伸岳 ([徳島大学.大学院社会産業理工学研究部.生物資源産業学域.応用生命系.応用生物資源学分野]/[徳島大学.生物資源産業学部.生物資源産業学科.応用生命講座])
役割 (任意): (英)   (日) 解析,考察   [継承]
貢献度 (任意):
学籍番号 (推奨):
[継承]
6.伊藤 博夫 ([徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.基礎歯学系.予防歯学])
役割 (任意): (英)   (日) 考察   [継承]
貢献度 (任意):
学籍番号 (推奨):
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7.松木 均 ([徳島大学.大学院社会産業理工学研究部.生物資源産業学域.応用生命系.応用生物資源学分野]/[徳島大学.生物資源産業学部.生物資源産業学科.応用生命講座])
役割 (任意): (英)   (日) 計画,考察,記述   [継承]
貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) Membrane fusion of phospholipid bilayers under high pressure: Spherical and irreversible growth of giant vesicles  (日)    [継承]
副題 (任意):
要約 (任意): (英) Membrane fusion of giant vesicles (GVs) for binary bilayers of unsaturated phospholipids, dioleoylphosphatidylethanolamine (DOPE) having an ability to promote membrane fusion and its homolog dioleoylphosphatidylcholine (DOPC) having an ability to form GV, was investigated under atmospheric and high pressure. While DOPC formed GVs in the presence of inorganic salts with a multivalent metal ion under atmospheric pressure, an equimolar mixture of DOPE and DOPC formed GVs both in the absence and the presence of LaCl3. We examined the change in size and shape of the GVs of this binary mixture in the absence and presence of LaCl3 as a function of time under atmospheric and high pressure. The size and shape of the GVs in the absence of LaCl3 under atmospheric and high pressure and those in the presence of LaCl3 under atmospheric pressure hardly changed with time. By contrast, the GV in the presence of LaCl3 under high pressure gradually changed in the size and shape with time on a time scale of several hours. Namely, the GV became larger than the original GV due to accelerated membrane fusion and its shape became more spherical. This pressure-induced membrane fusion was completely irreversible, and the growth rate was correlated with the applied pressure. The reason for the GV growth by applying pressure was considered on the basis of thermodynamic phase diagrams. We concluded that the growth is attributable to a closer packing of lipid molecules in the bilayer resulting from their preference of smaller volumes under high pressure. Furthermore, the molecular mechanism of the pressure-induced membrane fusion was explored by observing the fusion of two GVs with almost the same size. From their morphological changes, we revealed that the fusion is caused by the actions of Laplace and osmotic pressure.  (日)    [継承]
キーワード (推奨): 1. (英) Giant vesicle (日) (読) [継承]
2.高圧力 (high pressure) [継承]
3. (英) Laplace pressure (日) (読) [継承]
4. (英) Lipid bilayer membrane (日) (読) [継承]
5. (英) Osmotic pressure (日) (読) [継承]
6. (英) Membrane fusion (日) (読) [継承]
発行所 (推奨): Elsevier (->組織[Elsevier Science]) [継承]
誌名 (必須): Biophysical Chemistry ([Elsevier Science])
(pISSN: 0301-4622, eISSN: 1873-4200)

ISSN (任意): 1873-4200
ISSN: 0301-4622 (pISSN: 0301-4622, eISSN: 1873-4200)
Title: Biophysical chemistry
Title(ISO): Biophys Chem
Publisher: Elsevier BV
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 277 [継承]
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(必須): 106639-1 106639-11 [継承]
都市 (任意):
年月日 (必須): 西暦 2021年 10月 初日 (令和 3年 10月 初日) [継承]
URL (任意):
DOI (任意): 10.1016/j.bpc.2021.106639    (→Scopusで検索) [継承]
PMID (任意):
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備考 (任意): 1.(英) Article.Affiliation: Graduate School of Bioscience and Bioindustry, Tokushima University, 2-1 Minamijosanjima-cho, Tokushima 770-8513, Japan.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]

標準的な表示

和文冊子 ● Masaki GOTO, Akira Kazama, Kensuke Fukuhara, Honami Sato, Nobutake Tamai, Hiro-O Ito and Hitoshi Matsuki : Membrane fusion of phospholipid bilayers under high pressure: Spherical and irreversible growth of giant vesicles, Biophysical Chemistry, Vol.277, 106639-1-106639-11, 2021.
欧文冊子 ● Masaki GOTO, Akira Kazama, Kensuke Fukuhara, Honami Sato, Nobutake Tamai, Hiro-O Ito and Hitoshi Matsuki : Membrane fusion of phospholipid bilayers under high pressure: Spherical and irreversible growth of giant vesicles, Biophysical Chemistry, Vol.277, 106639-1-106639-11, 2021.

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