| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○招待 (推奨): |
| ○審査 (推奨): | □ | Peer Review
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| ○カテゴリ (推奨): | □ | 研究
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| ○共著種別 (推奨): |
| ○学究種別 (推奨): | □ | 博士後期課程学生による研究報告
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| ○組織 (推奨): | 1. | 徳島大学.大学院医歯薬学研究部.保健学域.保健科学部門.放射線科学系.医用画像機器工学 (2015年4月1日〜)
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| ○著者 (必須): | 1. | (英) Nakada Ryosei (日) 中田 良成 (読)
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| ○学籍番号 (推奨): | □ | ****
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| 2. | アボウ アルオラ オマル
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| 3. | 吉永 哲哉 ([徳島大学.大学院医歯薬学研究部.保健学域.保健科学部門.放射線科学系.医用画像機器工学])
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| ○題名 (必須): | □ | (英) Intensity-modulated radiation therapy optimization for acceptable and remaining-one unacceptable dose-volume and mean-dose constraint planning (日)
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| ○要約 (任意): | □ | (英) We give a novel approach for obtaining an intensity-modulated radiation therapy (IMRT) optimization solution based on the idea of continuous dynamical methods. The proposed method, which is an iterative algorithm derived from the discretization of a continuous-time dynamical system, can handle not only dose-volume but also mean-dose constraints directly in IMRT treatment planning. A theoretical proof for the convergence to an equilibrium corresponding to the desired IMRT planning is given by using the Lyapunov stability theorem. By introducing the concept of `acceptable', which means the existence of a nonempty set of beam weights satisfying the given dose-volume and mean-dose constraints, and by using the proposed method for an acceptable IMRT planning, one can resolve the issue that the objective and evaluation are different in the conventional planning process. Moreover, in the case where the target planning is totally unacceptable and partly acceptable except for one group of dose constraints, we give a procedure that enables us to obtain a nearly optimal solution close to the desired solution for unacceptable planning. The performance of the proposed approach for an acceptable or unacceptable planning is confirmed through numerical experiments simulating a clinical setup. (日)
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| ○キーワード (推奨): | 1. | (英) IMRT optimization (日) (読)
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| 2. | 非線形力学系 (nonlinear dynamical system)
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| 3. | (英) Lyapunov theorem (日) (読)
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| ○発行所 (推奨): | □ | (英) Hindawi (日) (読)
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| ○誌名 (必須): | □ | Computational and Mathematical Methods in Medicine (Hindawi)
(pISSN: 1748-670X, eISSN: 1748-6718)
| ○ISSN (任意): | □ | 1748-670X
ISSN: 1748-670X
(pISSN: 1748-670X, eISSN: 1748-6718) Title: Computational and mathematical methods in medicineTitle(ISO): Comput Math Methods MedPublisher: Hindawi (NLM Catalog)
(Scopus)
(CrossRef)
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| ○巻 (必須): | □ | 2020
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| ○号 (必須): | □ | Article ID 3096067
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| ○頁 (必須): | □ |
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| ○都市 (任意): | □ | (英) United Kingdom (日) (読)
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| ○年月日 (必須): | □ | 西暦 2020年 9月 3日 (令和 2年 9月 3日)
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| ○URL (任意): | □ | https://doi.org/10.1155/2020/3096067
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| ○DOI (任意): | □ | 10.1155/2020/3096067 (→Scopusで検索)
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| ○PMID (任意): | □ | 32963584 (→Scopusで検索)
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| ○Scopus (任意): | □ | 2-s2.0-85091567152
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