『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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言語 (必須): 英語 [継承]
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組織 (推奨):
著者 (必須): 1.松崎 利也
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2.岩佐 武 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.外科系.産科婦人科学])
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3. (英) Yanagihara Rie (日) (読)
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4. (英) Komasaka Mizuki (日) (読)
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5.矢野 清人
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学籍番号 (推奨): **** [ユーザ]
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6. (英) Mayila Yiliyasi (日) Mayila Yiliyasi (読) まいら いりやす
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学籍番号 (推奨): **** [ユーザ]
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7. (英) Tachibana Ayaka (日) (読)
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8.山本 由理 ([徳島大学.病院.先端医科医療開発研究プロジェクト]/[徳島大学.病院.診療科.小児·周産·女性科.産科婦人科])
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9.加藤 剛志 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.外科系.産科婦人科学])
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10.桑原 章
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11.苛原 稔 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.外科系.産科婦人科学])
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題名 (必須): (英) Pilot study of the optimal protocol of low dose step-up follicle stimulating hormone therapy for infertile women.  (日)    [継承]
副題 (任意):
要約 (任意): (英) To evaluate the optimized protocol of low dose follicle-stimulating hormone (FSH) therapy that has a starting dose of 50 IU/62.5 IU with a small increment dose (12.5 IU) for women with World Health Organization (WHO) II ovulatory disorder and unexplained infertility. Anovulatory women with WHO group II ovulatory disorder (ovulation induction [OI] patients, n = 29), and with an unexplained infertility (ovarian stimulation [OS] patients, n = 21) were enrolled. The protocol of low dose step-up FSH therapy was optimized for the starting dose as 50 IU (body mass index [BMI] < 20 group) and 62.5 IU (BMI ≥ 20 group) with the increment dose of 12.5 IU. Study outcomes were ovulation, monofollicular development and other variables. In the OIpatients, the ovulation rate was 100% (BMI < 20 group) and 90.9% (BMI ≥ 20 group). Monofollicular development was 80.0% (BMI < 20) and 77.3% (BMI ≥ 20). The pregnancy rate was 60% (3/5 BMI < 20) and 18.2% (4/22 BMI ≥ 20). There was no multiple pregnancy. In the OSpatients, the ovulation rate was 100%. Monofollicular development was 85.7% (BMI < 20) and 76.6% (BMI ≥ 20). No pregnancy was achieved in the OSpatients. Optimized protocol of low dose FSH therapy setting a starting dose 50 IU/62.5 IU by BMI with an increment dose of 12.5 IU was safe and highly effective in WHO group II anovulatory patients. However, this protocol seemed uneffective for patients with unexplained infertility.  (日)    [継承]
キーワード (推奨):
発行所 (推奨):
誌名 (必須): Reproductive Medicine and Biology (日本生殖医学会/日本アンドロロジー学会/日本受精着床学会)
(pISSN: 1445-5781, eISSN: 1447-0578)

ISSN (任意): 1445-5781
ISSN: 1445-5781 (pISSN: 1445-5781, eISSN: 1447-0578)
Title: Reproductive medicine and biology
Title(ISO): Reprod Med Biol
Publisher: Springer Science+Business Media
 (NLM Catalog  (医中誌Web  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 17 [継承]
(必須): 3 [継承]
(必須): 315 324 [継承]
都市 (任意):
年月日 (必須): 西暦 2018年 6月 12日 (平成 30年 6月 12日) [継承]
URL (任意):
DOI (任意): 10.1002/rmb2.12208    (→Scopusで検索) [継承]
PMID (任意): 30013434    (→Scopusで検索) [継承]
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備考 (任意): 1.(英) Article.ELocationID: 10.1002/rmb2.12208  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) KeywordList.Keyword: WHO group II  (日)    [継承]
4.(英) KeywordList.Keyword: low dose FSH  (日)    [継承]
5.(英) KeywordList.Keyword: ovarian stimulation  (日)    [継承]
6.(英) KeywordList.Keyword: ovulation induction  (日)    [継承]
7.(英) KeywordList.Keyword: polycystic ovary syndrome  (日)    [継承]

標準的な表示

和文冊子 ● (種別) : Toshiya Matsuzaki, Takeshi Iwasa, Rie Yanagihara, Mizuki Komasaka, Kiyohito Yano, Yiliyasi Mayila, Ayaka Tachibana, Yuri Yamamoto, Takeshi Katou, Akira Kuwahara and Minoru Irahara : Pilot study of the optimal protocol of low dose step-up follicle stimulating hormone therapy for infertile women., Reproductive Medicine and Biology, Vol.17, No.3, 315-324, (発行所), (都市), June 2018.
欧文冊子 ● (種別) : Toshiya Matsuzaki, Takeshi Iwasa, Rie Yanagihara, Mizuki Komasaka, Kiyohito Yano, Yiliyasi Mayila, Ayaka Tachibana, Yuri Yamamoto, Takeshi Katou, Akira Kuwahara and Minoru Irahara : Pilot study of the optimal protocol of low dose step-up follicle stimulating hormone therapy for infertile women., Reproductive Medicine and Biology, Vol.17, No.3, 315-324, (発行所), (都市), June 2018.

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