『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=351772EID:351772, Map:0, LastModified:2019年8月15日(木) 15:50:34, Operator:[松崎 利也], Avail:TRUE, Censor:0, Owner:[苛原 稔], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
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カテゴリ (推奨):
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組織 (推奨):
著者 (必須): 1. (英) Kasai Kana (日) 笠井 可菜 (読) かさい かな
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学籍番号 (推奨): **** [ユーザ]
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2.加藤 剛志 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.外科系.産科婦人科学])
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3. (英) Kadota Yuri (日) (読)
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4. (英) Erdenebayar Otgontsetseg (日) Otgontsetseg Erdenebayar (読) おとごんつぇつぇぐ えれでねばやる
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学籍番号 (推奨): **** [ユーザ]
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5. (英) Keyama Kaoru (日) 毛山 薫 (読) けやま かおる
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学籍番号 (推奨): **** [ユーザ]
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6.河北 貴子 ([徳島大学.病院.中央診療施設等.地域産婦人科診療部])
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学籍番号 (推奨): **** [ユーザ]
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7.吉田 加奈子 ([徳島大学.病院.中央診療施設等.周産母子センター])
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8.桑原 章
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9.松崎 利也
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10.苛原 稔 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.外科系.産科婦人科学])
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題名 (必須): (英) Intraperitoneal administration of activin A promotes development of endometriotic lesions in a mouse model of endometriosis.  (日)    [継承]
副題 (任意):
要約 (任意): (英) This study aimed to investigate the effect of intraperitoneal administration of activin on the occurrence of endometriosis using a mouse model of endometriosis. A mouse model of endometriosis was prepared by intraperitoneally administering endometrial tissue and blood collected from donor mice to C57BL/6J 7-8- week-old recipient mice. A total of 400 μg of activin A was intraperitoneally administered to model mice in the activin group for 5 days. Intraperitoneal endometriotic lesions were confirmed macroscopically and IL-6 and TNF-α levels in washed ascites were measured by ELISA. Endometriotic lesions were observed in all mice. In the activin group, the maximum diameter of endometriotic lesions was significantly larger than that in control group (4.7?1.3 vs 2.9?0.9 mm, p?0.01). The total area of the lesion was also significantly higher in the activin group than in the control group (21.1?9.9 vs 8.8?5.4 mm,p?0.01). Furthermore, IL-6 and TNF-α levels in ascites were significantly higher in the activin group than in the control group (IL-6 : 85.8?15.3 vs 75.1?19.3 pg/ml, p?0.05 ; TNF-α : 629.8?15.4 vs 605.9?11.4 pg/ml, p?0.05). Activin promotes occurrence of endometriosis. Inflammatory cytokines are also elevated by activin administration,suggesting that they may contribute to progression of endometriosis J. Med. Invest. 66 : 123-127, February, 2019.  (日)    [継承]
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誌名 (必須): The Journal of Medical Investigation : JMI ([徳島大学.医学部])
(pISSN: 1343-1420, eISSN: 1349-6867)

ISSN (任意): 1349-6867
ISSN: 1343-1420 (pISSN: 1343-1420, eISSN: 1349-6867)
Title: The journal of medical investigation : JMI
Title(ISO): J Med Invest
Supplier: 徳島大学
Publisher: Tokushima Daigaku Igakubu
 (NLM Catalog  (Webcat Plus  (医中誌Web  (J-STAGE  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 123 127 [継承]
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年月日 (必須): 西暦 2019年 2月 初日 (平成 31年 2月 初日) [継承]
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DOI (任意): 10.2152/jmi.66.123    (→Scopusで検索) [継承]
PMID (任意): 31064924    (→Scopusで検索) [継承]
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備考 (任意): 1.(英) Article.ELocationID: 10.2152/jmi.66.123  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) KeywordList.Keyword: Activin A  (日)    [継承]
4.(英) KeywordList.Keyword: Endometriosis  (日)    [継承]
5.(英) KeywordList.Keyword: Inflammatory cytokine  (日)    [継承]
6.(英) KeywordList.Keyword: Mouse model  (日)    [継承]

標準的な表示

和文冊子 ● Kana Kasai, Takeshi Katou, Yuri Kadota, Otgontsetseg Erdenebayar, Kaoru Keyama, Takako Kawakita, Kanako Yoshida, Akira Kuwahara, Toshiya Matsuzaki and Minoru Irahara : Intraperitoneal administration of activin A promotes development of endometriotic lesions in a mouse model of endometriosis., The Journal of Medical Investigation : JMI, Vol.66, No.1.2, 123-127, 2019.
欧文冊子 ● Kana Kasai, Takeshi Katou, Yuri Kadota, Otgontsetseg Erdenebayar, Kaoru Keyama, Takako Kawakita, Kanako Yoshida, Akira Kuwahara, Toshiya Matsuzaki and Minoru Irahara : Intraperitoneal administration of activin A promotes development of endometriotic lesions in a mouse model of endometriosis., The Journal of Medical Investigation : JMI, Vol.66, No.1.2, 123-127, 2019.

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