『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=340930EID:340930, Map:0, LastModified:2019年3月2日(土) 20:41:48, Operator:[[ADMIN]], Avail:TRUE, Censor:0, Owner:[楠瀬 賢也], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨): 研究 [継承]
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1.楠瀬 賢也 ([徳島大学.病院.診療科.内科.循環器内科])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
2. (英) Obuchowski A. Nancy (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
3. (英) Gillinov Marc (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
4. (英) Popovic B. Zoran (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
5. (英) Flamm D. Scott (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
6. (英) Griffin P. Brian (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
7. (英) Kwon H. Deborah (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) Predictors of Mortality in Patients With Severe Ischemic Cardiomyopathy Undergoing Surgical Mitral Valve Intervention.  (日)    [継承]
副題 (任意):
要約 (任意): (英) Ischemic mitral regurgitation is associated with substantial risk of death. Although surgical mitral valve intervention (MVi) may improve symptoms, it has not been shown to improve survival. The aim of this study was to identify predictors of mortality in patients with ischemic mitral regurgitation and MVi. We evaluated 117 consecutive patients (age, 65±10 years) with advanced ischemic cardiomyopathy who underwent cardiac magnetic resonance and subsequent MVi between January 1, 2002 and January 1, 2012. Cardiac magnetic resonance was used to assess left ventricular remodeling and myocardial scarring. The effective regurgitant orifice area was calculated from the proximal isovelocity surface area by echocardiography. There were 43 deaths (37%) during follow-up (median, 62 months). On multivariable analysis, age ≥70 years (=0.013), diabetes mellitus (=0.001), dyslipidemia (=0.012), papillary muscle scar (=0.010), incomplete revascularization (=0.001), and total scar %×effective regurgitant orifice area ≥0.20 cm (=0.005) were each independently associated with all-cause mortality. Although patients with effective regurgitant orifice area <0.2 cm at baseline demonstrated an increased hazard ratio of 3.3 for every 10% increase in scar, the hazard ratio increased to 9 for every 10% increase in scar in those with baseline effective regurgitant orifice area ≥0.20 cm. Mortality also was significantly higher in patients with incomplete revascularization compared with those with vascularized viable myocardium (61% versus 28%; <0.001). Increased total scar burden and the presence of incomplete revascularization are powerful predictors of mortality in patients with advanced ischemic cardiomyopathy undergoing MVi. Viability assessment with cardiac magnetic resonance imaging can identify which patients with ischemic mitral regurgitation are at highest risk for mortality after surgical MVi.  (日)    [継承]
キーワード (推奨): 1. (英) Aged (日) (読) [継承]
2. (英) Cardiomyopathies (日) (読) [継承]
3. (英) Cause of Death (日) (読) [継承]
4. (英) Echocardiography (日) (読) [継承]
5. (英) Female (日) (読) [継承]
6. (英) Follow-Up Studies (日) (読) [継承]
7. (英) Heart Valve Prosthesis Implantation (日) (読) [継承]
8. (英) Humans (日) (読) [継承]
9. (英) Magnetic Resonance Imaging, Cine (日) (読) [継承]
10. (英) Male (日) (読) [継承]
11. (英) Middle Aged (日) (読) [継承]
12. (英) Mitral Valve (日) (読) [継承]
13. (英) Mitral Valve Insufficiency (日) (読) [継承]
14.心筋虚血 (myocardial ischemia) [継承]
15. (英) Retrospective Studies (日) (読) [継承]
16. (英) Risk Assessment (日) (読) [継承]
17. (英) Risk Factors (日) (読) [継承]
18. (英) Severity of Illness Index (日) (読) [継承]
19. (英) Survival Rate (日) (読) [継承]
20. (英) United States (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Journal of the American Heart Association ([American Heart Association]/American Stroke Association)
(eISSN: 2047-9980)

ISSN (任意): 2047-9980
ISSN: 2047-9980 (eISSN: 2047-9980)
Title: Journal of the American Heart Association
Title(ISO): J Am Heart Assoc
Publisher: American Heart Association
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
[継承]
[継承]
(必須): 6 [継承]
(必須): 11 [継承]
(必須): e007163 e007163 [継承]
都市 (任意):
年月日 (必須): 西暦 2017年 11月 17日 (平成 29年 11月 17日) [継承]
URL (任意):
DOI (任意): 10.1161/JAHA.117.007163    (→Scopusで検索) [継承]
PMID (任意): 29150492    (→Scopusで検索) [継承]
NAID (任意):
WOS (任意):
Scopus (任意): 2-s2.0-85034775846 [継承]
機関リポジトリ : 113032 [継承]
評価値 (任意):
被引用数 (任意):
指導教員 (推奨):
備考 (任意): 1.(英) Article.ELocationID: e007163  (日)    [継承]
2.(英) Article.ELocationID: 10.1161/JAHA.117.007163  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
4.(英) Article.PublicationTypeList.PublicationType: Observational Study  (日)    [継承]
5.(英) KeywordList.Keyword: ischemic cardiomyopathy  (日)    [継承]
6.(英) KeywordList.Keyword: magnetic resonance imaging  (日)    [継承]
7.(英) KeywordList.Keyword: mitral valve regurgitation  (日)    [継承]
8.(英) KeywordList.Keyword: myocardial delayed enhancement  (日)    [継承]
9.(英) KeywordList.Keyword: revascularization  (日)    [継承]

標準的な表示

和文冊子 ● Kenya Kusunose, Nancy A. Obuchowski, Marc Gillinov, Zoran B. Popovic, Scott D. Flamm, Brian P. Griffin and Deborah H. Kwon : Predictors of Mortality in Patients With Severe Ischemic Cardiomyopathy Undergoing Surgical Mitral Valve Intervention., Journal of the American Heart Association, Vol.6, No.11, e007163, 2017.
欧文冊子 ● Kenya Kusunose, Nancy A. Obuchowski, Marc Gillinov, Zoran B. Popovic, Scott D. Flamm, Brian P. Griffin and Deborah H. Kwon : Predictors of Mortality in Patients With Severe Ischemic Cardiomyopathy Undergoing Surgical Mitral Valve Intervention., Journal of the American Heart Association, Vol.6, No.11, e007163, 2017.

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