| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○著者 (必須): | 1. | (英) Namba Mitsuyoshi (日) (読)
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| 2. | (英) Iwakura Toshio (日) (読)
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| 3. | (英) Nishimura Rimei (日) (読)
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| 4. | (英) Akazawa Kohei (日) (読)
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| 5. | 松久 宗英 ([徳島大学.先端酵素学研究所.基幹研究部門]/徳島大学病院アンチエイジングセンター センター長(併任)/徳島大学先端酵素学研究所長(併任))
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| 6. | (英) Atsumi Yoshihito (日) (読)
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| 7. | (英) Satoh Jo (日) (読)
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| 8. | (英) Yamauchi Toshimasa (日) (読)
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| ○題名 (必須): | □ | (英) The current status of treatment-related severe hypoglycemia in Japanese patients with diabetes mellitus: A report from the committee on a survey of severe hypoglycemia in the Japan Diabetes Society. (日)
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| ○要約 (任意): | □ | (英) ) than among those with type 1 diabetes (73.3 [53.5-91.1] mL/min/1.73 m (日) ) (P < 0.001). Again, the median HbA1c value at onset of severe hypoglycemia was shown to be 7.0 (6.3-8.1)% among all patients examined, 7.5 (6.9-8.6)% among those with type 1 diabetes, and 6.8 (6.1-7.6)% among those with type 2 diabetes, with the HbA1c value at onset of hypoglycemia being significantly lower among those with type 2 diabetes (P < 0.001). Antecedent symptoms of severe hypoglycemia were shown to be present, absent and unknown in 35.5, 35.6, and 28.9% of all patients, respectively, with the incidence of symptomatic hypoglycemia being significantly lower among those with type 1 diabetes (41.0%) than among those with type 2 diabetes (56.9%). The antidiabetic agents used in those with type 2 diabetes were insulin preparations (292 patients including 29 receiving concomitant sulfonylureas [SUs]) (60.8%), SUs (159 insulin-naïve patients) (33.1%), and no insulin preparations or SUs (29 patients) (6.0%). Of the 798 patients surveyed, 296 patients (37.2%) were shown to have required emergency transportation services for severe hypoglycemia before. Thus, the survey revealed, for the first time, the current status of treatment-related severe hypoglycemia in Japan and clearly highlights the acute need for implementing preventive measures against hypoglycemia not only through education on hypoglycemia but through optimization of antidiabetic therapy for those at high risk of severe hypoglycemia or those with a history of severe hypoglycemia.
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| ○キーワード (推奨): |
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| ○誌名 (必須): | □ | Journal of Diabetes Investigation (Asian Association for the Study of Diabetes)
(pISSN: 2040-1116, eISSN: 2040-1124)
| ○ISSN (任意): | □ | 2040-1124
ISSN: 2040-1116
(pISSN: 2040-1116, eISSN: 2040-1124) Title: Journal of diabetes investigationTitle(ISO): J Diabetes InvestigPublisher: John Wiley and Sons Inc (NLM Catalog)
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| ○年月日 (必須): | □ | 西暦 2018年 3月 2日 (平成 30年 3月 2日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1111/jdi.12790 (→Scopusで検索)
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| ○PMID (任意): | □ | 29498232 (→Scopusで検索)
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| ○備考 (任意): | 1. | (英) PublicationType: Journal Article (日)
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