○種別 (必須): | □ | 学術論文 (審査論文)
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○言語 (必須): | □ | 英語
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○著者 (必須): | 1. | 新村 貴博 ([徳島大学.病院.中央診療施設等.総合臨床研究センター])
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| 2. | 座間味 義人
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| 3. | (英) Imai Toru (日) (読)
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| 4. | (英) Ito Tsuyoshi (日) (読)
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| 5. | (英) Sagara Hidenori (日) (読)
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| 6. | (英) Hiroyuki Hichiya (日) (読)
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| 7. | (英) Esumi Satoru (日) (読)
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| 8. | 武智 研志
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| 9. | 今西 正樹 ([徳島大学.大学院医歯薬学研究部.薬学域.先端薬学教育研究プロジェクト]/[徳島大学.大学院医歯薬学研究部.薬学域.薬科学部門.生命薬学系.医薬品機能生化学])
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| 10. | (英) Koyama Toshihiro (日) (読)
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| 11. | (英) Amano Manabu (日) (読)
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| 12. | (英) Kurata Naomi (日) (読)
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| 13. | (英) Kitamura Yoshihisa (日) (読)
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| 14. | (英) Nakura Hironori (日) (読)
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| 15. | (英) Sendo Toshiaki (日) (読)
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| 16. | 石澤 啓介 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.内科系.臨床薬理学])
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○題名 (必須): | □ | (英) Administration of Kampo medicine through a tube at an advanced critical care center. (日)
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○要約 (任意): | □ | (英) n emergency and critical care medical centers, tube administration is employed for patients who have difficulty swallowing oral drugs owing to decreased consciousness or mechanical ventilation. However, tube clogging due to drug injection is a concern. We compared the crushing method with the simple suspension method for the passage of amlodipine, an antihypertensive drug, in combination with rikkunshito, which has been used to treat upper gastrointestinal disorders such as functional dyspepsia and gastroesophageal reflux in emergency and critical care medical centers, to ascertain the effect of Kampo products on the passage of other drugs during tube administration. When the crushing method was employed, poorly water-soluble solid products were formed, while a uniformly dispersed suspension was obtained using the simple suspension method. In addition, the passage rate of amlodipine through the tube was 64% and 93% in the crushing and simple suspension methods, respectively, thereby indicating that the simple suspension method provided more favorable than the crushing method. The results of this study suggested that the passage rate of amlodipine for patients who received Kampo products concurrently was higher when the simple suspension method was used, and an appropriate drug amount might well be able to administered to patients using this method. J. Med. Invest. 65:32-36, February, 2018. (日)
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○誌名 (必須): | □ | The Journal of Medical Investigation : JMI ([徳島大学.医学部])
(pISSN: 1343-1420, eISSN: 1349-6867)
○ISSN (任意): | □ | 1349-6867
ISSN: 1343-1420
(pISSN: 1343-1420, eISSN: 1349-6867) Title: The journal of medical investigation : JMITitle(ISO): J Med InvestSupplier: 徳島大学Publisher: University of Tokushima (NLM Catalog)
(Webcat Plus)
(医中誌Web)
(J-STAGE)
(Scopus)
(CrossRef)
(Scopus information is found. [need login])
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○巻 (必須): | □ | 65
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○号 (必須): | □ | 1.2
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○頁 (必須): | □ | 32 36
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○年月日 (必須): | □ | 西暦 2018年 0月 初日 (平成 30年 0月 初日)
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○URL (任意): |
○DOI (任意): | □ | 10.2152/jmi.65.32 (→Scopusで検索)
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○PMID (任意): | □ | 29593190 (→Scopusで検索)
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○機関リポジトリ : | □ | 111388
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○備考 (任意): | 1. | (英) PublicationType: Journal Article (日)
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