| ○種別 (必須): | □ | 学術論文 (審査論文)
| [継承] |
| ○言語 (必須): | □ | 英語
| [継承] |
| ○招待 (推奨): |
| ○審査 (推奨): |
| ○カテゴリ (推奨): |
| ○共著種別 (推奨): |
| ○学究種別 (推奨): |
| ○組織 (推奨): |
| ○著者 (必須): | 1. | (英) Tsutsumi Toshihiko (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 2. | (英) Okamoto Yoko (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 3. | (英) Yamakawa Syougo (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 4. | (英) Bingjun Cheng (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 5. | (英) Ishihara Akira (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 6. | 田中 保 ([徳島大学.大学院社会産業理工学研究部.生物資源産業学域.食料科学系.食料科学分野])
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 7. | 德村 彰
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| ○題名 (必須): | □ | (英) Reduced rat plasma lysophosphatidylglycerol or lysophosphatidic acid level as a biomarker of aristolochic acid-induced renal and adipose dysfunctions. (日)
| [継承] |
| ○副題 (任意): |
| ○要約 (任意): | □ | (英) Food products and diet pills containing aristolochic acid (AA) are responsible for a rapid progression of nephropathy associated with reduced body weight in human beings. In this study, we investigated the relationship of dietary NaCl and lysophospholipid (LPL) plasma levels to body weight gain in AA-treated rats. Male rats receiving a salt-deficient chow, normal salt chow or high salt chow were injected intraperitoneally daily with AA for 15days. Body weight, visceral fat mass, food intake, levels of LPL in plasma and its synthesized enzyme were investigated. Body weight gain, visceral fat mass and daily food intake were smaller in AA-treated rats than those of control rats, regardless of dietary salt concentration. AA treatment decreased plasma levels of major lysophosphatidic acid (LPA) molecular species in rats fed the normal or high-salt chow but not the salt-deficient chow, whereas both the plasma lysophospholipase D activity and kidney mRNA level of autotaxin of AA-treated rats fed chow with defined salt concentrations were lower than those of control rats. Plasma levels of major molecular species of lysophosphatidylglycerol (LPG) in AA-treated rat groups fed chow with defined salt concentrations were lower than those of control rats. Plasma levels of LPG and LPA seem to be relevant to the reduced body weight gain and fat mass due to AA treatment. (日)
| [継承] |
| ○キーワード (推奨): | 1. | (英) Adipose Tissue (日) (読)
| [継承] |
| 2. | (英) Animals (日) (読)
| [継承] |
| 3. | (英) Aristolochic Acids (日) (読)
| [継承] |
| 4. | (英) Biomarkers (日) (読)
| [継承] |
| 5. | (英) Body Weight (日) (読)
| [継承] |
| 6. | (英) Feeding Behavior (日) (読)
| [継承] |
| 7. | (英) Kidney (日) (読)
| [継承] |
| 8. | (英) Lysophospholipids (日) (読)
| [継承] |
| 9. | (英) Male (日) (読)
| [継承] |
| 10. | (英) Organ Size (日) (読)
| [継承] |
| 11. | (英) Phosphoric Diester Hydrolases (日) (読)
| [継承] |
| 12. | (英) RNA, Messenger (日) (読)
| [継承] |
| 13. | (英) Rats (日) (読)
| [継承] |
| 14. | (英) Rats, Wistar (日) (読)
| [継承] |
| 15. | (英) Sodium Chloride, Dietary (日) (読)
| [継承] |
| ○発行所 (推奨): |
| ○誌名 (必須): | □ | Life Sciences ([Elsevier])
(pISSN: 0024-3205, eISSN: 1879-0631)
| ○ISSN (任意): | □ | 1879-0631
ISSN: 0024-3205
(pISSN: 0024-3205, eISSN: 1879-0631) Title: Life sciencesTitle(ISO): Life SciPublisher: Elsevier Inc. (NLM Catalog)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
| [継承] |
| ○巻 (必須): | □ | 157
| [継承] |
| ○号 (必須): |
| ○頁 (必須): | □ | 208 216
| [継承] |
| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2016年 6月 4日 (平成 28年 6月 4日)
| [継承] |
| ○URL (任意): |
| ○DOI (任意): | □ | 10.1016/j.lfs.2016.06.003 (→Scopusで検索)
| [継承] |
| ○PMID (任意): | □ | 27267499 (→Scopusで検索)
| [継承] |
| ○CRID (任意): |
| ○Scopus (任意): | 1. | 2-s2.0-84975841169
| [継承] |
| ○researchmap (任意): |
| ○評価値 (任意): |
| ○被引用数 (任意): |
| ○指導教員 (推奨): |
| ○備考 (任意): | 1. | (英) Article.ELocationID: 10.1016/j.lfs.2016.06.003 (日)
| [継承] |
| 2. | (英) Article.ELocationID: S0024-3205(16)30349-6 (日)
| [継承] |
| 3. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
| [継承] |
| 4. | (英) KeywordList.Keyword: Aristolochic acid nephropathy (日)
| [継承] |
| 5. | (英) KeywordList.Keyword: Body weight loss (日)
| [継承] |
| 6. | (英) KeywordList.Keyword: Dietary sodium (日)
| [継承] |
| 7. | (英) KeywordList.Keyword: Lysophosphatidic acid (日)
| [継承] |
| 8. | (英) KeywordList.Keyword: Lysophosphatidylglycerol (日)
| [継承] |
| 9. | (英) KeywordList.Keyword: Lysophospholipase D (日)
| [継承] |