| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○カテゴリ (推奨): | □ | 研究
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| ○組織 (推奨): |
| ○著者 (必須): | 1. | (英) Kadota Takako (日) (読)
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| 2. | 角田 奈美 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.外科系.麻酔・疼痛治療医学]/[徳島大学.病院.診療科.脳·神経·精神科.麻酔科])
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| 3. | (英) Horikawa T. Yousuke (日) (読)
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| 4. | 堤 理恵
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| 5. | 大山 拓朗
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| 6. | 田中 克哉 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.外科系.麻酔・疼痛治療医学]/[徳島大学.病院.診療科.脳·神経·精神科])
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| 7. | 堤 保夫
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| ○題名 (必須): | □ | (英) Plasma substance P concentrations in patients undergoing general anesthesia: an objective marker associated with postoperative nausea and vomiting (日)
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| ○要約 (任意): | □ | (英) This study investigated plasma concentrations of substance P (SP) in patients undergoing general anesthesia (GA) and postoperative nausea and vomiting (PONV). This prospective, observational, cohort study included 23 patients who underwent scheduled surgery under general anesthesia. Blood was collected from the radial artery at predetermined time points (15-30 mins prior anesthesia, 15-30 mins after surgery/GA, and 24 h after surgery). PONV, SP concentrations, risk factors, and analgesics used were measured. Nine of 23 patients experienced PONV. In patients without PONV, SP concentrations significantly decreased ( < 0.0001) at the end of surgery/GA, compared to baseline, and recovered at 24 h after surgery/GA (452.9 ± 146.2 vs. 666.9 ± 176.5 vs. 580.7 ± 168.6 pg/mL, respectively), whereas SP levels were unchanged during surgery/GA and increased at 24 hours after surgery ( = 0.020) in patients with PONV (726.1 ± 167.8 vs. 655.8 ± 168.0 vs. 779.7 ± 220.7 pg/mL, respectively). These finding suggest that SP levels may be utilized as an objective marker for PONV. (日)
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| ○キーワード (推奨): |
| ○発行所 (推奨): |
| ○誌名 (必須): | □ | JA Clinical Reports ([Springer])
(eISSN: 2363-9024)
| ○ISSN (任意): | □ | 2363-9024
ISSN: 2363-9024
(eISSN: 2363-9024) Title: JA clinical reportsTitle(ISO): JA Clin RepPublisher: Springer (NLM Catalog)
(Scopus)
(CrossRef)
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| ○巻 (必須): | □ | 2
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| ○号 (必須): | □ | 9
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| ○頁 (必須): | □ | 9 9
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2016年 6月 2日 (平成 28年 6月 2日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1186/s40981-016-0034-9 (→Scopusで検索)
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| ○PMID (任意): | □ | 29497664 (→Scopusで検索)
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| ○備考 (任意): | 1. | (英) Article.ELocationID: 9 (日)
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| 2. | (英) Article.ELocationID: 10.1186/s40981-016-0034-9 (日)
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| 3. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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| 4. | (英) KeywordList.Keyword: General anesthesia (日)
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| 5. | (英) KeywordList.Keyword: PONV (日)
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| 6. | (英) KeywordList.Keyword: Substance P (日)
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