| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○審査 (推奨): | □ | Peer Review
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| ○カテゴリ (推奨): | □ | 研究
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| ○共著種別 (推奨): | □ | 国内共著 (徳島大学内研究者と国内(学外)研究者との共同研究 (国外研究者を含まない))
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| ○学究種別 (推奨): | □ | 博士後期課程学生による研究報告
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| ○組織 (推奨): | 1. | 徳島大学
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| ○著者 (必須): | 1. | 長谷 栄治 ([徳島大学.ポストLEDフォトニクス研究所])
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| 2. | 佐藤 克也 ([徳島大学.大学院社会産業理工学研究部.理工学域.機械科学系.知能機械学分野]/[徳島大学.理工学部.理工学科.機械科学コース.知能機械学講座])
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| 3. | 米倉 大介 ([徳島大学.大学院社会産業理工学研究部.理工学域.機械科学系.生産工学分野]/[徳島大学.理工学部.理工学科.機械科学コース.生産工学講座])
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| 4. | 南川 丈夫
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| 5. | 高橋 光彦
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| 6. | 安井 武史 ([徳島大学.ポストLEDフォトニクス研究所]/[徳島大学.理工学部.理工学科.機械科学コース.生産工学講座])
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| ○題名 (必須): | □ | (英) Evaluation of the histological and mechanical features of tendon healing in a rabbit model with the use of second-harmonic-generation imaging and tensile testing (日)
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| ○要約 (任意): | □ | (英) This study aimed to evaluate the histological and mechanical features of tendon healing in a rabbit model with second-harmonic-generation (SHG) imaging and tensile testing. A total of eight male Japanese white rabbits were used for this study. The flexor digitorum tendons in their right leg were sharply transected, and then were repaired by intratendinous stitching. At four weeks post-operatively, the rabbits were killed and the flexor digitorum tendons in both right and left legs were excised and used as specimens for tendon healing (n = 8) and control (n = 8), respectively. Each specimen was examined by SHG imaging, followed by tensile testing, and the results of the two testing modalities were assessed for correlation. While the SHG light intensity of the healing tendon samples was significantly lower than that of the uninjured tendon samples, 2D Fourier transform SHG images showed a clear difference in collagen fibre structure between the uninjured and the healing samples, and among the healing samples. The mean intensity of the SHG image showed a moderate correlation (R(2) = 0.37) with Young's modulus obtained from the tensile testing. Our results indicate that SHG microscopy may be a potential indicator of tendon healing.Cite this article: E. Hase, K. Sato, D. Yonekura, T. Minamikawa, M. Takahashi, T. Yasui. Evaluation of the histological and mechanical features of tendon healing in a rabbit model with the use of second-harmonic-generation imaging and tensile testing. Bone Joint Res 2016;5:577-585. DOI: 10.1302/2046-3758.511.BJR-2016-0162.R1. (日)
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| ○キーワード (推奨): |
| ○発行所 (推奨): | □ | (英) British Editorial Society of Bone & Joint Surgery (日) (読)
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| ○誌名 (必須): | □ | Bone & Joint Research (British Editorial Society of Bone and Joint Surgery)
(eISSN: 2046-3758)
| ○ISSN (任意): | □ | 2046-3758
ISSN: 2046-3758
(eISSN: 2046-3758) Title: Bone & joint researchTitle(ISO): Bone Joint ResPublisher: British Editorial Society of Bone and Joint Surgery (NLM Catalog)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
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| ○巻 (必須): | □ | 5
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| ○号 (必須): | □ | 11
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| ○頁 (必須): | □ | 577 585
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| ○年月日 (必須): | □ | 西暦 2016年 11月 23日 (平成 28年 11月 23日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1302/2046-3758.511.BJR-2016-0162.R1 (→Scopusで検索)
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| ○PMID (任意): | □ | 27881441 (→Scopusで検索)
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| ○備考 (任意): | 1. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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| 2. | (英) KeywordList.Keyword: Collagen (日)
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| 3. | (英) KeywordList.Keyword: Healing (日)
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| 4. | (英) KeywordList.Keyword: Second-harmonic-generation microscopy (日)
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| 5. | (英) KeywordList.Keyword: Tendon (日)
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| 6. | (英) KeywordList.Keyword: Tensile testing (日)
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| 7. | (英) CoiStatement: ICMJE COI Statement: None declared (日)
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