『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
ID: Pass:

登録内容 (EID=323024)

EID=323024EID:323024, Map:0, LastModified:2018年11月29日(木) 11:57:42, Operator:[[ADMIN]], Avail:TRUE, Censor:承認済, Owner:[齊藤 達哉], Read:継承, Write:継承, Delete:継承.
○種別 (必須): □学術論文 (審査論文) [継承]
○言語 (必須): □英語 [継承]
○招待 (推奨):
○審査 (推奨):
○カテゴリ (推奨):
○共著種別 (推奨): □国内共著 (徳島大学内研究者と国内(学外)研究者との共同研究 (国外研究者を含まない)) [継承]
○学究種別 (推奨):
○組織 (推奨):
○著者 (必須): 1. (英) Imagawa Yusuke (日) (読)
○役割 (任意):
○貢献度 (任意):
○学籍番号 (推奨):
[継承]
2.齊藤 達哉
○役割 (任意):
○貢献度 (任意):
○学籍番号 (推奨):
[継承]
3. (英) Tsujimoto Yoshihide (日) (読)
○役割 (任意):
○貢献度 (任意):
○学籍番号 (推奨):
[継承]
○題名 (必須): □(英) Vital staining for cell death identifies Atg9a-dependent necrosis in developmental bone formation in mouse.  (日)    [継承]
○副題 (任意):
○要約 (任意): □(英) Programmed cell death has a crucial role in various biological events, including developmental morphogenesis. Recent evidence indicates that necrosis contributes to programmed cell death in addition to apoptosis, but it is unclear whether necrosis acts as a compensatory mechanism for failure of apoptosis or has an intrinsic role during development. In contrast to apoptosis, there have been no techniques for imaging physiological necrosis in vivo. Here we employ vital staining using propidium iodide to identify cells with plasma membrane disruption (necrotic cells) in mouse embryos. We discover a form of necrosis at the bone surface, which does not occur in embryos with deficiency of the autophagy-related gene Atg9a, although it is unaffected by Atg5 knockout. We also find abnormalities of the bone surface in Atg9a knockout mice, suggesting an important role of Atg9a-dependent necrosis in bone surface formation. These findings suggest that necrosis has an active role in developmental morphogenesis.  (日)    [継承]
○キーワード (推奨):
○発行所 (推奨):
○誌名 (必須): □Nature Communications ([Nature Publishing Group])
(eISSN: 2041-1723)

○ISSN (任意): □2041-1723
ISSN: 2041-1723 (eISSN: 2041-1723)
Title: Nature communications
Title(ISO): Nat Commun
Publisher: Nature Portfolio
 (NLM Catalog)   (Scopus)   (CrossRef)  (Scopus information is found. [need login])
[継承]
[継承]
○巻 (必須): □7 [継承]
○号 (必須):
○頁 (必須): □13391 13391 [継承]
○都市 (任意):
○年月日 (必須): □西暦 2016年 11月 4日 (平成 28年 11月 4日) [継承]
○URL (任意):
○DOI (任意): □10.1038/ncomms13391    (→Scopusで検索) [継承]
○PMID (任意): □27811852    (→Scopusで検索) [継承]
○CRID (任意):
○WOS : □000387009300001 [継承]
○Scopus (任意): 1.2-s2.0-84994634404 [継承]
○機関リポジトリ : □112448 [継承]
○researchmap (任意):
○評価値 (任意):
○被引用数 (任意):
○指導教員 (推奨):
○備考 (任意): 1.(英) PublicationType: Journal Article  (日)    [継承]

標準的な表示

和文冊子 ● Yusuke Imagawa, Tatsuya Saitoh and Yoshihide Tsujimoto : Vital staining for cell death identifies Atg9a-dependent necrosis in developmental bone formation in mouse., Nature Communications, 7, (号), 13391, 2016.
欧文冊子 ● Yusuke Imagawa, Tatsuya Saitoh and Yoshihide Tsujimoto : Vital staining for cell death identifies Atg9a-dependent necrosis in developmental bone formation in mouse., Nature Communications, 7, (号), 13391, 2016.

関連情報

Number of session users = 2, LA = 1.61, Max(EID) = 467923, Max(EOID) = 1243747.