『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
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カテゴリ (推奨):
共著種別 (推奨): 国内共著 (徳島大学内研究者と国内(学外)研究者との共同研究 (国外研究者を含まない)) [継承]
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1. (英) Nakano Sei-ichi. (日) (読)
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2.岩﨑 英隆
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3.近藤 英司 ([徳島大学.病院.診療科.感覚·皮膚·運動機能科.耳鼻咽喉科・頭頸部外科])
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4.宮崎 かつし
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5.雫 治彦
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6. (英) Kamimura Sei-ichirou (日) (読)
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7. (英) Fukuda Junya (日) (読)
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8. (英) Kanamura Ryou (日) (読)
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9.武田 憲昭 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.外科系.耳鼻咽喉科学])
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題名 (必須): (英) Efficacy of proton pump inhibitor in combination with rikkunshito in patients complaining of globus pharyngeus  (日)    [継承]
副題 (任意):
要約 (任意): (英) Globus pharyngeus (GP) is a common symptom of laryngopharyngeal reflux disease (LPRD), and proton pump inhibitor (PPI) and rikkunshito, a traditional Japanese medicine having prokinetic effect improve LPRD symptoms. In the present study, we examined the efficacy of high-dose PPI in combination with rikkunshito in patients complaining of GP. 106 patients complaining of GP without any organic endoscopic findings were enrolled. Patients were first administrated with high-dose PPI alone for 4 to 8 weeks and the symptom was improved in 65 patients. Among 41 patients with PPI-refractory GP, 22 patients were administrated with high-dose PPI in combination with rikkunshito, and the symptom was improved in 14 of 22 patients 4 weeks later. The average value of a modified reflux symptom index of the responders was similar to that of non-responders. Only a few patients had positive values in reflux finding scores in both groups. The present findings suggest the existence of a high prevalence of LPRD in patients complaining of GP. The data also suggest that gastroesophageal dysmotility is involved in GP, in addition to excessive acid reflux. The pre-therapeutic laryngopharyngeal symptoms and endoscopic findings could not predict the efficacy of the treatment for GP. J. Med. Invest. 63: 227-229, August, 2016.  (日)    [継承]
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誌名 (必須): The Journal of Medical Investigation : JMI ([徳島大学.医学部])
(pISSN: 1343-1420, eISSN: 1349-6867)

ISSN (任意): 1349-6867
ISSN: 1343-1420 (pISSN: 1343-1420, eISSN: 1349-6867)
Title: The journal of medical investigation : JMI
Title(ISO): J Med Invest
Supplier: 徳島大学
Publisher: Tokushima Daigaku Igakubu
 (NLM Catalog  (Webcat Plus  (医中誌Web  (J-STAGE  (Scopus  (CrossRef (Scopus information is found. [need login])
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年月日 (必須): 西暦 2016年 8月 初日 (平成 28年 8月 初日) [継承]
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DOI (任意): 10.2152/jmi.63.227    (→Scopusで検索) [継承]
PMID (任意): 27644563    (→Scopusで検索) [継承]
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Scopus (任意): 2-s2.0-84987925216 [継承]
機関リポジトリ : 111185 [継承]
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備考 (任意): 1.(英) Article.ELocationID: 10.2152/jmi.63.227  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]

標準的な表示

和文冊子 ● Sei-ichi. Nakano, Hidetaka Iwasaki, Eiji Kondou, Katsushi Miyazaki, Haruhiko Shizuku, Sei-ichirou Kamimura, Junya Fukuda, Ryou Kanamura and Noriaki Takeda : Efficacy of proton pump inhibitor in combination with rikkunshito in patients complaining of globus pharyngeus, The Journal of Medical Investigation : JMI, Vol.63, No.3,4, 227-229, 2016.
欧文冊子 ● Sei-ichi. Nakano, Hidetaka Iwasaki, Eiji Kondou, Katsushi Miyazaki, Haruhiko Shizuku, Sei-ichirou Kamimura, Junya Fukuda, Ryou Kanamura and Noriaki Takeda : Efficacy of proton pump inhibitor in combination with rikkunshito in patients complaining of globus pharyngeus, The Journal of Medical Investigation : JMI, Vol.63, No.3,4, 227-229, 2016.

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