| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○招待 (推奨): |
| ○審査 (推奨): |
| ○カテゴリ (推奨): |
| ○共著種別 (推奨): | □ | 国内共著 (徳島大学内研究者と国内(学外)研究者との共同研究 (国外研究者を含まない))
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| ○学究種別 (推奨): |
| ○組織 (推奨): |
| ○著者 (必須): | 1. | 荻野 広和 ([徳島大学.病院.診療科.内科.呼吸器・膠原病内科])
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| ○学籍番号 (推奨): |
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| 2. | 埴淵 昌毅 ([徳島大学.大学院医歯薬学研究部.医学域.連携研究部門(医学域).寄附講座系(医学域).地域呼吸器・血液・代謝内科学])
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| 3. | 柿内 聡司
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| 4. | 西條 敦郎
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| 5. | 手塚 敏史
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| 6. | 豊田 優子
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| 7. | 飛梅 亮
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| ○貢献度 (任意): |
| ○学籍番号 (推奨): | □ | ****
| [ユーザ] |
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| 8. | (英) Otsuka Kenji (日) (読)
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| 9. | 坂口 暁
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| [継承] |
| 10. | 後東 久嗣
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| 11. | 有澤 孝吉
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| 12. | 西岡 安彦 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.内科系.呼吸器・膠原病内科学])
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| ○題名 (必須): | □ | (英) Analysis of the prognostic factors of extensive disease small-cell lung cancer patients in Tokushima University Hospital (日)
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| ○要約 (任意): | □ | (英) Small-cell lung cancer (SCLC) presents aggressive clinical behavior, and its prognosis is still poor. Previously, performance status (PS), or the existence of brain, bone, or liver metastasis were reported to be unfavorable prognostic factors. Given the recent progress of treatment modalities such as radiotherapy techniques and bone modifying agents, the prognostic factors might be different from previous findings. Therefore, we analyzed the prognostic factors of extensive disease SCLC (ED-SCLC) in recent years. ED-SCLC patients treated in Tokushima University Hospital between 2010 and 2016 were analyzed. Log-rank test and the Cox proportional hazards regression model was used in univariate and multivariate analysis, respectively. Totally, 79 patients were analyzed. In the univariate analysis, age, PS, interstitial pneumonia (IP), liver metastasis, pleural dissemination, neutrophil counts, hypoalbuminemia, hypercalcemia and several liver and biliary enzymes were identified as poor prognostic factors. In the multivariate analysis, age, PS, IP, and liver and biliary enzymes were identified. Moreover, the PS in patients with liver metastasis was significantly worsened. In this study, we newly demonstrated that IP was a significant poor prognostic factor of ED-SCLC. Although liver metastasis was not extracted in multivariate analysis, it may have an impact on the prognosis of ED-SCLC. J. Med. Invest. 63: 286-293, August, 2016. (日)
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| ○キーワード (推奨): |
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| ○誌名 (必須): | □ | The Journal of Medical Investigation : JMI ([徳島大学.医学部])
(pISSN: 1343-1420, eISSN: 1349-6867)
| ○ISSN (任意): | □ | 1349-6867
ISSN: 1343-1420
(pISSN: 1343-1420, eISSN: 1349-6867) Title: The journal of medical investigation : JMITitle(ISO): J Med InvestSupplier: 徳島大学Publisher: University of Tokushima (NLM Catalog)
(CiNii NCID)
(医中誌Web)
(J-STAGE)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
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| ○巻 (必須): | □ | 63
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| ○号 (必須): | □ | 3 4
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| ○頁 (必須): | □ | 286 293
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2016年 8月 末日 (平成 28年 8月 末日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.2152/jmi.63.286 (→Scopusで検索)
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| ○PMID (任意): | □ | 27644574 (→Scopusで検索)
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| ○CRID (任意): |
| ○Scopus (任意): | 1. | 2-s2.0-84987918312
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| ○機関リポジトリ : | □ | 111196
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| ○指導教員 (推奨): |
| ○備考 (任意): | 1. | (英) Article.ELocationID: 10.2152/jmi.63.286 (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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