| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○組織 (推奨): |
| ○著者 (必須): | 1. | (英) Shuang Yang (日) (読)
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| 2. | (英) Yizhen Lin (日) (読)
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| 3. | (英) Zhang Yufeng (日) (読)
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| 4. | 小林 真左子
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| 5. | (英) Sculean Anton (日) (読)
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| 6. | (英) Miron Richard J (日) (読)
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| ○題名 (必須): | □ | (英) In vitro characterization of an osteoinductive biphasic calcium phosphate in combination with recombinant BMP2. (日)
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| ○要約 (任意): | □ | (英) The results from the present study demonstrate that 1) the osteoinductive potential of BCP bone particles is equally as osteopromotive as rhBMP2 on in vitro osteoblast differentiation and 2) BCP particles in combination with rhBMP2 is able to further increase the osteopromotive differentiation of osteoblasts in vitro when compared to either rhBMP2 alone or BCP alone. Future animal testing is further required to investigate this combination approach on new bone formation. (日) rhBMP2 was able to significantly upregulate cell recruitment whereas the addition of BCP as well as BCP alone had no additional ability to improve osteoblast recruitment. Both BCP and rhBMP2 were able to significantly increase cell proliferation at 3 and 5 days post seeding and cell number was further enhanced when rhBMP2 was combined with BCP. In addition, the combination of rhBMP2 with BCP significantly improved ALP activity at 7 and 14 days post seeding, alizarin red staining at 14 days, and mRNA levels of Runx2, ALP and osteocalcin when compared to cells seeded with rhBMP2 alone or BCP alone.
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| ○誌名 (必須): | □ | BMC Oral Health ([BioMed Central Ltd.])
(eISSN: 1472-6831)
| ○ISSN (任意): | □ | 1472-6831
ISSN: 1472-6831
(eISSN: 1472-6831) Title: BMC oral healthTitle(ISO): BMC Oral HealthPublisher: BioMed Central (NLM Catalog)
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| ○巻 (必須): | □ | 17
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| ○号 (必須): | □ | 1
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| ○頁 (必須): | □ |
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| ○年月日 (必須): | □ | 西暦 2016年 8月 2日 (平成 28年 8月 2日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1186/s12903-016-0263-3 (→Scopusで検索)
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| ○PMID (任意): | □ | 27485617 (→Scopusで検索)
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| ○備考 (任意): | 1. | (英) PublicationType: Journal Article (日)
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