| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○学究種別 (推奨): |
| ○組織 (推奨): |
| ○著者 (必須): | 1. | (英) Sawada Kosaku (日) (読)
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| 2. | 小林 真左子
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| 3. | (英) Kobayashi Eizaburo (日) (読)
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| 4. | (英) Brömme Jens O (日) (読)
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| 5. | (英) Schaller Benoit (日) (読)
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| 6. | (英) Miron Richard J (日) (読)
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| ○題名 (必須): | □ | (英) In vitro effects of 0 to 120 Grays of irradiation on bone viability and release of growth factors. (日)
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| ○要約 (任意): | □ | (英) These results demonstrate the pronounced effects of irradiation on bone-cell vitality and subsequent release of growth factors. Interestingly, the largest observed change in gene expression was the 7-fold decrease in VEGF protein following irradiation. Future research aimed at improving our understanding of bone following irradiation is necessary to further improve future clinical treatments. (日) It was observed that at only 7.5Gy of irradiation, over 85 % of cells were non-vital and by 60 Gy, all cells underwent apoptosis. Furthermore, over a 7-fold decrease in VEGF and a 2-fold decrease in TGFβ1 were observed following irradiation at all tested doses. Little change was observed for BMP2 and IL1β whereas RANKL was significantly increased for all irradiated samples.
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| ○誌名 (必須): | □ | BMC Oral Health ([BioMed Central Ltd.])
(eISSN: 1472-6831)
| ○ISSN (任意): | □ | 1472-6831
ISSN: 1472-6831
(eISSN: 1472-6831) Title: BMC oral healthTitle(ISO): BMC Oral HealthPublisher: BioMed Central (NLM Catalog)
(Scopus)
(CrossRef)
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| ○巻 (必須): | □ | 17
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| ○号 (必須): | □ | 1
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| ○頁 (必須): | □ |
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| ○年月日 (必須): | □ | 西暦 2016年 7月 4日 (平成 28年 7月 4日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1186/s12903-016-0241-9 (→Scopusで検索)
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| ○PMID (任意): | □ | 27431387 (→Scopusで検索)
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| ○備考 (任意): | 1. | (英) PublicationType: Journal Article (日)
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