| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○審査 (推奨): | □ | Peer Review
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| ○カテゴリ (推奨): | □ | 研究
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| ○学究種別 (推奨): |
| ○組織 (推奨): |
| ○著者 (必須): | 1. | 小林 真左子
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| 2. | (英) Caballé-Serrano Jordi (日) (読)
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| 3. | (英) Bosshardt Dieter D (日) (読)
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| 4. | (英) Gruber Reinhard (日) (読)
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| 5. | (英) Buser Daniel (日) (読)
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| 6. | (英) Miron Richard J (日) (読)
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| ○題名 (必須): | □ | (英) Bone conditioned media (BCM) improves osteoblast adhesion and differentiation on collagen barrier membranes. (日)
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| ○要約 (任意): | □ | (英) The results from the present study suggest that the osteoconductive properties of porcine-derived barrier membranes could be further improved by BCM by significantly increasing cell attachment, differentiation and mineralization of osteoblasts in vitro. Future animal testing is required to fully characterize the additional benefits of BCM for guided bone regeneration. (日) SEM images demonstrated evidence of accumulated proteins found on the surface of collagen membranes following coating with BCM. Analysis of total cell numbers revealed that the additional pre-coating with BCM markedly increased cell attachment over 4 fold when compared to cells seeded on barrier membranes alone. No significant difference could be observed for cell proliferation at all time points. BCM significantly increased mRNA levels of osteoblast differentiation markers including ALP, OCN and BSP at 5 days post seeding. Furthermore, barrier membranes pre-coated with BCM demonstrated a 5-fold increase in alizarin red staining at 14 days.
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| ○キーワード (推奨): |
| ○発行所 (推奨): |
| ○誌名 (必須): | □ | BMC Oral Health ([BioMed Central Ltd.])
(eISSN: 1472-6831)
| ○ISSN (任意): | □ | 1472-6831
ISSN: 1472-6831
(eISSN: 1472-6831) Title: BMC oral healthTitle(ISO): BMC Oral HealthPublisher: BioMed Central (NLM Catalog)
(Scopus)
(CrossRef)
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| ○巻 (必須): | □ | 17
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| ○号 (必須): | □ | 1
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| ○頁 (必須): | □ |
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2016年 7月 4日 (平成 28年 7月 4日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1186/s12903-016-0230-z (→Scopusで検索)
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| ○PMID (任意): | □ | 27430310 (→Scopusで検索)
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| ○備考 (任意): | 1. | (英) PublicationType: Journal Article (日)
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