○種別 (必須): | □ | 学術論文 (審査論文)
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○言語 (必須): | □ | 英語
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○著者 (必須): | 1. | 峯田 一秀 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.外科系.形成外科学]/[徳島大学.病院.診療科.感覚·皮膚·運動機能科.形成外科・美容外科])
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| 2. | (英) Kubo S. (日) (読)
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| 3. | (英) Kato H. (日) (読)
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| 4. | (英) Kinoshita K. (日) (読)
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| 5. | (英) Doi K. (日) (読)
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| 6. | 橋本 一郎 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.外科系.形成外科学])
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| 7. | 中西 秀樹
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| 8. | (英) Yoshimura K. (日) (読)
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○題名 (必須): | □ | (英) Chronic inflammation and progressive calcification as a result of fat necrosis : the worst end in fat grafting. (日)
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○要約 (任意): | □ | (英) Autologous fat injection into the breast has been performed widely for breast augmentation and reconstruction because of recent technical and scientific advancements. However, it is important to learn what occurs and how problematic it can be if fat grafting is not conducted appropriately. Oil cysts were explanted from three subjects who underwent cosmetic fat grafting to the breast 2, 4, and 6 years previously. The oil cyst samples were examined histopathologically. Computed tomographic, magnetic resonance imaging, and mammographic images obtained sequentially after fat grafting were also analyzed. The cyst wall consisted of innermost and outermost fibrous layers and intermediate tissue that contained the regular adipose portion, a degenerated adipose portion, and a fibrous area. Eggshell-like macrocalcifications were seen in the inner surface. Numerous inflammatory cells, mainly MAC2/CD206 anti-inflammatory M2 macrophages, were observed in the degenerated adipose portion. Oil cysts with a longer history showed more calcifications in the innermost layer and a larger fibrous area adjacent to the degenerated fat portion than those with a shorter history. These histopathologic findings and clinical computed tomographic images revealed that oil cysts continued to be inflammatory and calcifications continued to develop over several years. After fat necrosis, long-term chronic inflammation persists and calcification seems to progress without limits. Oil cysts are the worst outcome of fat grafting and must be avoided by standardizing meticulous injection techniques. Therapeutic, V. (日)
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○キーワード (推奨): | 1. | (英) Adipose Tissue (日) (読)
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| 2. | (英) Adult (日) (読)
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| 3. | (英) Breast (日) (読)
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| 4. | (英) Breast Cyst (日) (読)
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| 5. | (英) Calcinosis (日) (読)
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| 6. | (英) Chronic Disease (日) (読)
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| 7. | (英) Fat Necrosis (日) (読)
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| 8. | (英) Female (日) (読)
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| 9. | (英) Follow-Up Studies (日) (読)
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| 10. | (英) Graft Survival (日) (読)
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| 11. | (英) Humans (日) (読)
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| 12. | (英) Magnetic Resonance Imaging (日) (読)
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| 13. | (英) Mammaplasty (日) (読)
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| 14. | (英) Necrosis (日) (読)
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| 15. | (英) Oils (日) (読)
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| 16. | (英) Transplantation, Autologous (日) (読)
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| 17. | (英) Young Adult (日) (読)
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○発行所 (推奨): |
○誌名 (必須): | □ | Plastic and Reconstructive Surgery (American Society of Plastic and Reconstructive Surgeons/American Association of Plastic Surgeons)
(pISSN: 0032-1052, eISSN: 1529-4242)
○ISSN (任意): | □ | 1529-4242
ISSN: 0032-1052
(pISSN: 0032-1052, eISSN: 1529-4242) Title: Plastic and reconstructive surgeryTitle(ISO): Plast Reconstr SurgPublisher: Lippincott Williams and Wilkins (NLM Catalog)
(Scopus)
(CrossRef)
(Scopus information is found. [need login])
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○巻 (必須): | □ | 133
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○号 (必須): | □ | 5
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○頁 (必須): | □ | 1064 1072
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○年月日 (必須): | □ | 西暦 2014年 5月 初日 (平成 26年 5月 初日)
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○URL (任意): |
○DOI (任意): | □ | 10.1097/PRS.0000000000000097 (→Scopusで検索)
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○PMID (任意): | □ | 24776542 (→Scopusで検索)
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○備考 (任意): | 1. | (英) Article.ELocationID: 10.1097/PRS.0000000000000097 (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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