| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○招待 (推奨): |
| ○審査 (推奨): |
| ○カテゴリ (推奨): |
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| ○学究種別 (推奨): |
| ○組織 (推奨): |
| ○著者 (必須): | 1. | (英) Muramatsu Masayoshi (日) (読)
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| ○学籍番号 (推奨): |
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| 2. | (英) Ohto Chikara (日) (読)
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| 3. | (英) Obata Shusei (日) (読)
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| 4. | 櫻谷 英治 ([徳島大学.大学院社会産業理工学研究部.生物資源産業学域.食料科学系.食料科学分野]/[徳島大学.生物資源産業学部.生物資源産業学科.食料科学コース])
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| 5. | (英) Shimizu Sakayu (日) (読)
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| ○題名 (必須): | □ | (英) Accumulation of prenyl alcohols by terpenoid biosynthesis inhibitors in various microorganisms. (日)
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| ○要約 (任意): | □ | (英) Squalene synthase inhibitors significantly accelerate the production of farnesol by various microorganisms. However, farnesol production by Saccharomyces cerevisiae ATCC 64031, in which the squalene synthase gene is deleted, was not affected by the inhibitors, indicating that farnesol accumulation is enhanced in the absence of squalene synthase activity. The combination of diphenylamine as an inhibitor of carotenoid biosynthesis and a squalene synthase inhibitor increases geranylgeraniol production by a yeast, Rhodotorula rubra NBRC 0870. An ent-kauren synthase inhibitor also enhances the production of farnesol and geranylgeraniol by a filamentous fungus, Gibberella fujikuroi NBRC 30336. These results indicate that the inhibition of downstream enzymes from prenyl diphosphate synthase leads to the production of farnesol and geranylgeraniol. (日)
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| ○キーワード (推奨): | 1. | (英) Alkyl and Aryl Transferases (日) (読)
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| 2. | (英) Biosynthetic Pathways (日) (読)
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| 3. | (英) Diphenylamine (日) (読)
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| 4. | (英) Diterpenes (日) (読)
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| 5. | (英) Enzyme Inhibitors (日) (読)
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| 6. | (英) Farnesol (日) (読)
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| 7. | (英) Farnesyl-Diphosphate Farnesyltransferase (日) (読)
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| 8. | (英) Fungi (日) (読)
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| 9. | (英) Terpenes (日) (読)
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| ○発行所 (推奨): |
| ○誌名 (必須): | □ | Applied Microbiology and Biotechnology ([Springer-Verlag])
(pISSN: 0175-7598, eISSN: 1432-0614)
| ○ISSN (任意): | □ | 1432-0614
ISSN: 0175-7598
(pISSN: 0175-7598, eISSN: 1432-0614) Title: Applied microbiology and biotechnologyTitle(ISO): Appl Microbiol BiotechnolSupplier: Springer Online Journal ArchivePublisher: Springer (NLM Catalog)
(Scopus)
(CrossRef)
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| ○巻 (必須): | □ | 80
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| ○号 (必須): | □ | 4
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| ○頁 (必須): | □ | 589 595
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2008年 7月 18日 (平成 20年 7月 18日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1007/s00253-008-1578-z (→Scopusで検索)
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| ○PMID (任意): | □ | 18636253 (→Scopusで検索)
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| ○備考 (任意): | 1. | (英) PublicationType: Journal Article (日)
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