| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○著者 (必須): | 1. | 酒井 徹 ([徳島大学.大学院医歯薬学研究部.医学域.栄養科学部門.医科栄養学系.実践栄養学])
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| 2. | (英) Furoku Sakina (日) (読)
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| 3. | (英) Nakamoto Mariko (日) (読)
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| 4. | 首藤 恵泉
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| 5. | 保坂 利男
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| 6. | 西岡 安彦 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.内科系.呼吸器・膠原病内科学])
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| 7. | 曽根 三郎
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| ○題名 (必須): | □ | (英) The Soy isoflavone equol enhances antigen-specific IgE production in ovalbumin-immunized BALB/c mice. (日)
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| ○要約 (任意): | □ | (英) Although an immunomodulatory role of the soy isoflavone genistein has been demonstrated, the effects of other soy isoflavones on induction of antigen (Ag)-specific immune responses are not known. In this study, we therefore investigated the effects of daidzein and equol on ovalbumin (OVA)-specific T cell and B cell responses in BALB/c mice. Mice that had been treated with 20 mg/kg equol showed a significantly higher level of OVA-specific IgE than control mice. Levels of interferon (IFN)-gamma and interleukin (IL)-4 production were not different between the control and equol groups. However, IL-13 production level in mice administered 20 mg/kg equol was significantly higher than that in control mice. Strong induction of OVA-specific IgE production by equol was also observed in ovariectomized BALB/c mice, suggesting that the immunomodulatory effect of equol is not affected by endogenous estrogen. (日)
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| ○キーワード (推奨): |
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| ○誌名 (必須): | □ | Journal of Nutritional Science and Vitaminology ([日本栄養·食糧学会]/[日本ビタミン学会])
(pISSN: 0301-4800, eISSN: 1881-7742)
| ○ISSN (任意): | □ | 1881-7742
ISSN: 0301-4800
(pISSN: 0301-4800, eISSN: 1881-7742) Title: Journal of nutritional science and vitaminologyTitle(ISO): J Nutr Sci Vitaminol (Tokyo)Supplier: 日本ビタミン学会Publisher: Center for Academic Publications Japan (NLM Catalog)
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| ○巻 (必須): | □ | 56
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| ○号 (必須): | □ | 1
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| ○頁 (必須): | □ | 72 76
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2010年 0月 初日 (平成 22年 0月 初日)
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| ○DOI (任意): | □ | 10.3177/jnsv.56.72 (→Scopusで検索)
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| ○PMID (任意): | □ | 20354350 (→Scopusで検索)
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| ○WOS (任意): | □ | 000275240700012
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| ○備考 (任意): | 1. | (英) Article.Affiliation: Department of Public Health and Applied Nutrition, Institute for Health Biosciences, The University of Tokushima, Tokushima, Japan. tohrus@nutr.me.tokushima-u.ac.jp (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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| 3. | (英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't (日)
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