『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=193500EID:193500, Map:0, LastModified:2018年5月23日(水) 17:08:35, Operator:[[ADMIN]], Avail:TRUE, Censor:0, Owner:[橋本 一郎], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
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カテゴリ (推奨):
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学究種別 (推奨):
組織 (推奨):
著者 (必須): 1.松尾 伸二
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2.栗崎 晃
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3.杉野 弘
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4.橋本 一郎 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.外科系.形成外科学])
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5.中西 秀樹
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題名 (必須): (英) Analysis of skin graft survival using green fluores cent protein transgenic mice  (日) GFP トランスジェニックマウスを用いた皮膚移植の生着の分析   [継承]
副題 (任意):
要約 (任意): (英) Skin grafting has become a basic and established operation technique; however, it is not clear how skin grafts adapt to recipient beds and replace their functions. In this study, we analyzed the origin of cells in adapted transplants by using green fluorescent protein (GFP) transgenic mice, which emits green fluorescence in the whole body. The dorsal skins of GFP transgenic mice were transplanted to the back of wild-type mice. Similarly, wild-type skins were transplanted to the back of GFP transgenic mice. Since transplantation with full thickness back skin was not successful due to severe immunorejection, tail skins, which contain fewer epidermal Langerhans cells, were used for the experiments. Six months after transplantation, immunohistochemical analysis of the grafts revealed that tissues derived from ectodermal origin such as the epidermis, hair follicles, and sebaceous glands survived in transplanted grafts, but that other tissues such as the dermis, nerves and blood vessels are partly replaced by tissues from recipient beds. Our results further demonstrated that transplantation analyses with GFP transgenic mice could be a useful approach to study the origin of cells in transplants.  (日)    [継承]
キーワード (推奨): 1. (英) Animals (日) (読) [継承]
2. (英) Graft Survival (日) (読) [継承]
3. (英) Green Fluorescent Proteins (日) (読) [継承]
4. (英) Immunohistochemistry (日) (読) [継承]
5. (英) Mice (日) (読) [継承]
6. (英) Mice, Inbred C57BL (日) (読) [継承]
7. (英) Mice, Transgenic (日) (読) [継承]
8. (英) Recombinant Proteins (日) (読) [継承]
9. (英) Skin Transplantation (日) (読) [継承]
発行所 (推奨):
誌名 (必須): The Journal of Medical Investigation : JMI ([徳島大学.医学部])
(pISSN: 1343-1420, eISSN: 1349-6867)

ISSN (任意): 1343-1420
ISSN: 1343-1420 (pISSN: 1343-1420, eISSN: 1349-6867)
Title: The journal of medical investigation : JMI
Title(ISO): J Med Invest
Supplier: 徳島大学
Publisher: Tokushima Daigaku Igakubu
 (NLM Catalog  (Webcat Plus  (医中誌Web  (J-STAGE  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 54 [継承]
(必須): 3,4 [継承]
(必須): 267 275 [継承]
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年月日 (必須): 西暦 2007年 8月 初日 (平成 19年 8月 初日) [継承]
URL (任意):
DOI (任意): 10.2152/jmi.54.267    (→Scopusで検索) [継承]
PMID (任意): 17878676    (→Scopusで検索) [継承]
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機関リポジトリ : 111523 [継承]
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備考 (任意): 1.(英) Article.Affiliation: Department of Plastic and Reconstructive Surgery, Institute of Health Biosciences The University of Tokushima Graduate School, Tokushima, Japan.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Shinji Matsuo, Akira Kurisaki, Hiromu Sugino, Ichiro Hashimoto and Hideki Nakanishi : Analysis of skin graft survival using green fluores cent protein transgenic mice, The Journal of Medical Investigation : JMI, Vol.54, No.3,4, 267-275, 2007.
欧文冊子 ● Shinji Matsuo, Akira Kurisaki, Hiromu Sugino, Ichiro Hashimoto and Hideki Nakanishi : Analysis of skin graft survival using green fluores cent protein transgenic mice, The Journal of Medical Investigation : JMI, Vol.54, No.3,4, 267-275, 2007.

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