| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○招待 (推奨): |
| ○審査 (推奨): | □ | Peer Review
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| ○カテゴリ (推奨): | □ | 研究
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| ○著者 (必須): | 1. | 竹内 麻由美 ([徳島大学.病院.診療科.放射線科.放射線診断科])
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| 2. | 原田 雅史 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.内科系.放射線医学])
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| 3. | 松崎 健司
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| 4. | 西谷 弘
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| 5. | 森 健治 ([徳島大学.大学院医歯薬学研究部.保健学域.保健科学部門.看護学系.子どもの保健・看護学]/[徳島大学.医学部.保健学科.看護学専攻.母性·小児看護学講座])
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| ○題名 (必須): | □ | (英) Difference of signal change by a language task on autistic patients using functional MRI (日)
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| ○要約 (任意): | □ | (英) OBJECTIVE: Cerebral function with a language task was evaluated by functional magnetic resonance imaging (MRI), and the differences of activated pattern and signal changes were compared between autistic patients and normal controls. METHODS: Ten autistic and ten normal subjects were tested by fMRI with a language task requiring the attribution of complex mental states. Activation maps analyzed between two groups were generated and the asymmetry indexes calculated by the quotient of activated pixels of the right frontal lobe divided by those of the left frontal lobe were statistically compared by unpaired t-test. RESULTS: Both the autistic and the normal subjects showed activation at the bilateral prefrontal cortical areas and the ventral occipito-temporal regions. However, the autistic patients demonstrated more activation at the right frontal lobe than the normal controls. Thus it was considered that in the autistic patients the right-hemisphere was more dominant for the language task than that of the normal controls. The result is consist to the theory that autism is related to early left-hemisphere dysfunction. CONCLUSIONS: We considered that fMRI may be a useful non-invasive method to evaluate the cerebral functional abnormality in autistic patients. (日)
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| ○キーワード (推奨): | 1. | (英) Adolescent (日) (読)
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| 2. | (英) Autistic Disorder (日) (読)
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| 3. | (英) Brain (日) (読)
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| 4. | (英) Case-Control Studies (日) (読)
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| 5. | (英) Child (日) (読)
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| 6. | (英) Female (日) (読)
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| 7. | (英) Humans (日) (読)
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| 8. | (英) Language (日) (読)
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| 9. | (英) Language Tests (日) (読)
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| 10. | (英) Magnetic Resonance Imaging (日) (読)
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| 11. | (英) Male (日) (読)
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| ○発行所 (推奨): |
| ○誌名 (必須): | □ | The Journal of Medical Investigation : JMI ([徳島大学.医学部])
(pISSN: 1343-1420, eISSN: 1349-6867)
| ○ISSN (任意): | □ | 1343-1420
ISSN: 1343-1420
(pISSN: 1343-1420, eISSN: 1349-6867) Title: The journal of medical investigation : JMITitle(ISO): J Med InvestSupplier: 徳島大学Publisher: Tokushima Daigaku Igakubu (NLM Catalog)
(Webcat Plus)
(医中誌Web)
(J-STAGE)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
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| ○巻 (必須): | □ | 51
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| ○号 (必須): | □ | 1-2
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| ○頁 (必須): | □ | 59 62
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2004年 2月 初日 (平成 16年 2月 初日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.2152/jmi.51.59 (→Scopusで検索)
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| ○PMID (任意): | □ | 15000257 (→Scopusで検索)
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| ○機関リポジトリ : | □ | 110715
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| ○備考 (任意): | 1. | (英) Article.Affiliation: Department of Radiology, School of Health Sciences, The University of Tokushima School of Medicine, Tokushima, Japan. (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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