『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=136618EID:136618, Map:0, LastModified:2017年12月4日(月) 14:07:35, Operator:[[ADMIN]], Avail:TRUE, Censor:0, Owner:[谷 憲治], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
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共著種別 (推奨):
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組織 (推奨):
著者 (必須): 1. (英) Kimura Makoto (日) (読)
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2.谷 憲治 ([徳島大学.病院.中央診療施設等.総合診療部]/[徳島大学.大学院医歯薬学研究部.医学域.連携研究部門(医学域).寄附講座系(医学域).総合診療医学])
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3. (英) Miyata Junya (日) (読)
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4. (英) Sato Keiko (日) (読)
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5. (英) Hayashi Akihito (日) (読)
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6. (英) Otsuka Shinsaku (日) (読)
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7.浦田 知之
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8.曽根 三郎
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題名 (必須): (英) The significance of cathepsins, thrombin and aminopeptidase in diffuse interstitial lung diseases  (日)    [継承]
副題 (任意):
要約 (任意): (英) To determine the significance of proteases in interstitial lung diseases, we examined the activity of cathepsins, thrombin, and aminopeptidase in bronchoalveolar lavage (BAL) fluid from patients with these disorders. Significantly increased activities of cathepsin H and aminopeptidase were detected in BAL fluid from patients with idiopathic pulmonary fibrosis (IPF), cryptogenic organizing pneumonia (COP), chronic eosinophilic pneumonia (CEP) and hypersensitivity pneumonitis (HP). Significantly higher activity of cathepsin B was found in BAL fluid from patients with CEP. The activity of thrombin was significantly higher in patients with IPF and CEP. In patients with IPF, there were significant correlations between neutrophil number and the activity of cathepsin B, cathepsin H or aminopeptidase. In patients with COP and HP, the activity of the proteases was significantly higher in patients with higher number of lymphocytes than in those with lower number of lymphocytes. The present study suggests that the activity of the proteases is a useful marker in activity of the interstitial lung diseases, and may have a role in the pathogenesis of these disorders.  (日)    [継承]
キーワード (推奨): 1. (英) interstitial lung diseases (日) (読) [継承]
2. (英) cathepsin H (日) (読) [継承]
3. (英) cathepsin B (日) (読) [継承]
4. (英) cathepsin G (日) (読) [継承]
5. (英) thrombin (日) (読) [継承]
6. (英) aminopeptidase (日) (読) [継承]
発行所 (推奨): (英) The University of Tokushima (日) 徳島大学 (読) [継承]
誌名 (必須): The Journal of Medical Investigation : JMI ([徳島大学.医学部])
(pISSN: 1343-1420, eISSN: 1349-6867)

ISSN (任意): 1343-1420
ISSN: 1343-1420 (pISSN: 1343-1420, eISSN: 1349-6867)
Title: The journal of medical investigation : JMI
Title(ISO): J Med Invest
Supplier: 徳島大学
Publisher: Tokushima Daigaku Igakubu
 (NLM Catalog  (Webcat Plus  (医中誌Web  (J-STAGE  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 52 [継承]
(必須): 1,2 [継承]
(必須): 93 100 [継承]
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年月日 (必須): 西暦 2005年 2月 初日 (平成 17年 2月 初日) [継承]
URL (任意): http://ci.nii.ac.jp/naid/110002261672/ [継承]
DOI (任意): 10.2152/jmi.52.93    (→Scopusで検索) [継承]
PMID (任意): 15751279    (→Scopusで検索) [継承]
NAID (任意): 110002261672 [継承]
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機関リポジトリ : 110762 [継承]
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備考 (任意): 1.(英) Article.Affiliation: Department of Internal Medicine and Molecular Therapeutics, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Makoto Kimura, Kenji Tani, Junya Miyata, Keiko Sato, Akihito Hayashi, Shinsaku Otsuka, Tomoyuki Urata and Saburo Sone : The significance of cathepsins, thrombin and aminopeptidase in diffuse interstitial lung diseases, The Journal of Medical Investigation : JMI, Vol.52, No.1,2, 93-100, 2005.
欧文冊子 ● Makoto Kimura, Kenji Tani, Junya Miyata, Keiko Sato, Akihito Hayashi, Shinsaku Otsuka, Tomoyuki Urata and Saburo Sone : The significance of cathepsins, thrombin and aminopeptidase in diffuse interstitial lung diseases, The Journal of Medical Investigation : JMI, Vol.52, No.1,2, 93-100, 2005.

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