『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=98244EID:98244, Map:0, LastModified:2012年11月2日(金) 22:00:28, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[細井 和雄], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨): Peer Review [継承]
カテゴリ (推奨):
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著者 (必須): 1.姚 陳娟 ([徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.基礎歯学系.口腔分子生理学])
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2. (英) Wei Wei (日) (読)
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3.李 雪飛
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4.細井 和雄
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題名 (必須): (英) Acute phase protein induction by experimental inflammation in the salivary gland  (日)    [継承]
副題 (任意):
要約 (任意): (英) The submandibular gland (SMG) is a major salivary gland, which plays an important role in maintenance the oral health. In this study, we intended to explore the role of the SMG's defense system of the animals in which experimental inflammation is induced. The levels of mRNAs for inflammation cytokines and acute phase proteins were detected by reverse transcriptase-polymerase chain reaction (RT-PCR). The mRNAs for acute phase proteins were found to be increased in the SMG and extraorbital and intraorbital lacrimal gland (ELG and ILG) of rats at 24 h after subcutaneous injection of turpentine oil. The induction of mRNA for these inflammatory proteins by turpentine oil was preceded by a transient increase in the level of mRNAs for IL-1beta, IL-6 and TNF-alpha at 6 h after subcutaneous injection of the oil. Such cytokine induction was similarly seen by lipopolysaccharide (LPS) injection, and involvement of Toll-like receptor 4 (TLR4) was strongly suggested from experiment using C3H/HeJ mice, a TLR4-deficient mutant strain. The up-regulation of acute phase proteins and inflammation cytokines in the SMG, ELG and ILG by experimental inflammation suggests the existence of a strict defense system via the innate immune system in the SMG and other exocrine gland.  (日)    [継承]
キーワード (推奨): 1. (英) Acute-Phase Proteins (日) (読) [継承]
2. (英) Animals (日) (読) [継承]
3. (英) Cysteine Proteinase Inhibitors (日) (読) [継承]
4. (英) Cytokines (日) (読) [継承]
5. (英) Interleukin-1 (日) (読) [継承]
6. (英) Interleukin-6 (日) (読) [継承]
7. (英) Irritants (日) (読) [継承]
8. (英) Kininogens (日) (読) [継承]
9. (英) Lacrimal Apparatus (日) (読) [継承]
10. (英) Lipopolysaccharides (日) (読) [継承]
11. (英) Male (日) (読) [継承]
12. (英) Membrane Glycoproteins (日) (読) [継承]
13. (英) Mice (日) (読) [継承]
14. (英) Mice, Inbred C3H (日) (読) [継承]
15. (英) Mice, Inbred Strains (日) (読) [継承]
16. (英) Mice, Mutant Strains (日) (読) [継承]
17. (英) Rats (日) (読) [継承]
18. (英) Rats, Wistar (日) (読) [継承]
19. (英) Receptors, Cell Surface (日) (読) [継承]
20. (英) Sialadenitis (日) (読) [継承]
21. (英) Submandibular Gland Diseases (日) (読) [継承]
22. (英) Time Factors (日) (読) [継承]
23. (英) Toll-Like Receptor 4 (日) (読) [継承]
24. (英) Toll-Like Receptors (日) (読) [継承]
25. (英) Tumor Necrosis Factor-alpha (日) (読) [継承]
26. (英) Turpentine (日) (読) [継承]
27. (英) Up-Regulation (日) (読) [継承]
発行所 (推奨): Blackwell Publishing Ltd [継承]
誌名 (必須): Journal of Oral Pathology & Medicine (International Association of Oral Pathologists/American Academy of Oral Pathology)
(pISSN: 0904-2512, eISSN: 1600-0714)

ISSN (任意): 0904-2512
ISSN: 0904-2512 (pISSN: 0904-2512, eISSN: 1600-0714)
Title: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Title(ISO): J Oral Pathol Med
Supplier: International Association of Oral Pathologists
Publisher: Blackwell
 (NLM Catalog  (Wiley  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 34 [継承]
(必須): 6 [継承]
(必須): 364 367 [継承]
都市 (任意): (英) Oxford (日) (読) [継承]
年月日 (必須): 西暦 2005年 7月 初日 (平成 17年 7月 初日) [継承]
URL (任意):
DOI (任意): 10.1111/j.1600-0714.2005.00321.x    (→Scopusで検索) [継承]
PMID (任意): 15946185    (→Scopusで検索) [継承]
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備考 (任意): 1.(英) Article.Affiliation: Department of Molecular Oral Physiology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima-shi, Tokushima, 770-8504, Japan.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]

標準的な表示

和文冊子 ● Chenjuan Yao, Wei Wei, Xuefei Li and Kazuo Hosoi : Acute phase protein induction by experimental inflammation in the salivary gland, Journal of Oral Pathology & Medicine, Vol.34, No.6, 364-367, 2005.
欧文冊子 ● Chenjuan Yao, Wei Wei, Xuefei Li and Kazuo Hosoi : Acute phase protein induction by experimental inflammation in the salivary gland, Journal of Oral Pathology & Medicine, Vol.34, No.6, 364-367, 2005.

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