| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○招待 (推奨): |
| ○審査 (推奨): | □ | Peer Review
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| ○カテゴリ (推奨): |
| ○共著種別 (推奨): |
| ○学究種別 (推奨): |
| ○組織 (推奨): | 1. | 徳島大学.大学院ヘルスバイオサイエンス研究部.プロテオミクス医科学部門.生体制御医学講座 (2004年4月1日〜)
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| ○著者 (必須): | 1. | 西村 範行
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| ○学籍番号 (推奨): |
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| 2. | (英) Plutner Helen (日) (読)
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| 3. | (英) Hahn Klaus (日) (読)
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| ○貢献度 (任意): |
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| 4. | (英) Balch E. William (日) (読)
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| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
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| ○題名 (必須): | □ | (英) The d subunit of AP-3 is required for efficient transport of VSV-G from the trans-Golgi network to the cell surface (日)
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| ○副題 (任意): |
| ○要約 (任意): | □ | (英) Vesicular stomatitis virus glycoprotein (VSV-G) is a transmembrane protein that functions as the surface coat of enveloped viral particles. We report the surprising result that VSV-G uses the tyrosine-based di-acidic motif (-YTDIE-) found in its cytoplasmic tail to recruit adaptor protein complex 3 for export from the trans-Golgi network. The same sorting code is used to recruit coat complex II to direct efficient transport from the endoplasmic reticulum to the Golgi apparatus. These results demonstrate that a single sorting sequence can interact with sequential coat machineries to direct transport through the secretory pathway. We propose that use of this compact sorting domain reflects a need for both efficient endoplasmic reticulum export and concentration of VSV-G into specialized post-trans-Golgi network secretory-lysosome type transport containers to facilitate formation of viral coats at the cell surface. (日)
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| ○キーワード (推奨): | 1. | (英) Adaptor Protein Complex 3 (日) (読)
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| 2. | (英) Adaptor Protein Complex beta Subunits (日) (読)
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| 3. | (英) Adaptor Protein Complex delta Subunits (日) (読)
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| 4. | (英) Animals (日) (読)
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| 5. | (英) Antigens, CD (日) (読)
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| 6. | (英) Binding Sites (日) (読)
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| 7. | (英) Biological Transport (日) (読)
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| 8. | (英) Cell Membrane (日) (読)
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| 9. | (英) Cytoplasm (日) (読)
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| 10. | (英) Fibroblasts (日) (読)
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| 11. | (英) HeLa Cells (日) (読)
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| 12. | (英) Humans (日) (読)
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| 13. | (英) Kinetics (日) (読)
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| 14. | (英) Lysosome-Associated Membrane Glycoproteins (日) (読)
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| 15. | (英) Membrane Glycoproteins (日) (読)
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| 16. | (英) Mice (日) (読)
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| 17. | (英) Mice, Inbred C57BL (日) (読)
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| 18. | (英) Transcription Factors (日) (読)
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| 19. | (英) Vesicular stomatitis Indiana virus (日) (読)
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| 20. | (英) Viral Envelope Proteins (日) (読)
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| 21. | (英) trans-Golgi Network (日) (読)
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| ○発行所 (推奨): |
| ○誌名 (必須): | □ | Proceedings of the National Academy of Sciences of the United States of America ([The National Academy of Sciences of the United States of America])
(pISSN: 0027-8424, eISSN: 1091-6490)
| ○ISSN (任意): | □ | 0027-8424
ISSN: 0027-8424
(pISSN: 0027-8424, eISSN: 1091-6490) Title: Proceedings of the National Academy of Sciences of the United States of AmericaTitle(ISO): Proc Natl Acad Sci U S APublisher: National Academy of Sciences (NLM Catalog)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
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| ○巻 (必須): | □ | 99
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| ○号 (必須): | □ | 10
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| ○頁 (必須): | □ | 6755 6760
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2002年 5月 14日 (平成 14年 5月 14日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1073/pnas.092150699 (→Scopusで検索)
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| ○PMID (任意): | □ | 11997454 (→Scopusで検索)
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| ○NAID (任意): |
| ○WOS (任意): | □ | 000175637300044
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| ○Scopus (任意): | □ | 2-s2.0-0037076273
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| ○評価値 (任意): |
| ○被引用数 (任意): |
| ○指導教員 (推奨): |
| ○備考 (任意): | 1. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't (日)
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| 3. | (英) Article.PublicationTypeList.PublicationType: Research Support, U.S. Gov't, P.H.S. (日)
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| 4. | (英) OtherID: PMC124475 (日)
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