『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
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審査 (推奨): Peer Review [継承]
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組織 (推奨): 1.大学院ヘルスバイオサイエンス研究部.プロテオミクス医科学部門.生体制御医学講座 (2004年4月1日〜) [継承]
著者 (必須): 1. (英) Ewis A Ashraf (日) (読)
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2. (英) Lee Juwon (日) (読)
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3.新家 利一
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4.中堀 豊
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題名 (必須): (英) Two Y-chromosome-specific polymorphisms 12f2 and DFFRY in the Japanese population and their relations to other Y-polymorphisms  (日)    [継承]
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要約 (任意): (英) This study of male-specific genetic markers in the Japanese population was carried out in an attempt to refine the existing theories concerning its population genetics and migration events. We examined the relation between the constructed haplotypes of three biallelic Y-chromosome-specific markers (YAP, 47z and SRY) and the results of studying two other Y-specific polymorphisms of both 12f2 and DFFRY markers. The 12f2 marker was completely absent in 14.7% of Japanese males; all of them were haplotype II males. None of the Japanese males from other haplotypes or other East Asian populations showed any deletion of 12f2. In all haplotype II Japanese men, we found that DFFRY gene harbors a (C-->T) substitution polymorphism that was not found in any other population of this study. These results suggested that although haplotype II Japanese males share with the other haplotype II men from different geographical areas in having the YAP insertion on their Y-chromosomes, their Y-chromosomal structure is somewhat characteristically different. They are probably descendants of the ancestral Jomonese population who lived in Japan before the Yayoi immigrants entered Japan approximately 2300 years ago. These findings suggested that linkage studies between Y-specific markers are helpful in understanding the migratory patterns in East Asia. We also suggested that Japanese males have characteristically different Y-chromosomes compared with other populations.  (日)    [継承]
キーワード (推奨): 1. (英) Alleles (日) (読) [継承]
2. (英) Asian Continental Ancestry Group (日) (読) [継承]
3. (英) Female (日) (読) [継承]
4. (英) Genetic Markers (日) (読) [継承]
5. (英) Haplotypes (日) (読) [継承]
6. (英) Humans (日) (読) [継承]
7. (英) Japan (日) (読) [継承]
8. (英) Male (日) (読) [継承]
9. (英) Phylogeny (日) (読) [継承]
10. (英) Polymorphism, Genetic (日) (読) [継承]
11. (英) Y Chromosome (日) (読) [継承]
発行所 (推奨):
誌名 (必須): The Journal of Medical Investigation : JMI ([徳島大学.医学部])
(pISSN: 1343-1420, eISSN: 1349-6867)

ISSN (任意): 1343-1420
ISSN: 1343-1420 (pISSN: 1343-1420, eISSN: 1349-6867)
Title: The journal of medical investigation : JMI
Title(ISO): J Med Invest
Supplier: 徳島大学
Publisher: Tokushima Daigaku Igakubu
 (NLM Catalog  (Webcat Plus  (医中誌Web  (J-STAGE  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 49 [継承]
(必須): 1-2 [継承]
(必須): 44 50 [継承]
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年月日 (必須): 西暦 2002年 2月 初日 (平成 14年 2月 初日) [継承]
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PMID (任意): 11901759    (→Scopusで検索) [継承]
NAID (任意): 110001900977 [継承]
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機関リポジトリ : 110634 [継承]
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備考 (任意): 1.(英) Article.Affiliation: Department of Public Health, University of Tokushima School of Medicine, Kuramoto-cho, Tokushima 770-8503, Japan.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Comparative Study  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
4.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Ashraf A Ewis, Juwon Lee, Toshikatsu Shinka and Yutaka Nakahori : Two Y-chromosome-specific polymorphisms 12f2 and DFFRY in the Japanese population and their relations to other Y-polymorphisms, The Journal of Medical Investigation : JMI, Vol.49, No.1-2, 44-50, 2002.
欧文冊子 ● Ashraf A Ewis, Juwon Lee, Toshikatsu Shinka and Yutaka Nakahori : Two Y-chromosome-specific polymorphisms 12f2 and DFFRY in the Japanese population and their relations to other Y-polymorphisms, The Journal of Medical Investigation : JMI, Vol.49, No.1-2, 44-50, 2002.

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