『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
ID: Pass:

登録内容 (EID=95855)

EID=95855EID:95855, Map:0, LastModified:2012年9月14日(金) 16:30:02, Operator:[三木 ちひろ], Avail:TRUE, Censor:0, Owner:[[副研究部長]/[大学院ヘルスバイオサイエンス研究部]], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨): Peer Review [継承]
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨): 1.大学院ヘルスバイオサイエンス研究部.プロテオミクス医科学部門.生体制御医学講座 (2004年4月1日〜) [継承]
著者 (必須): 1. (英) Ewis A. Ashraf (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
2. (英) Lee W. Juwon (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
3. (英) Kuroki Yoko (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
4.新家 利一
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
5.中堀 豊
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) Yfm1, a multicopy marker specific for the Y chromosome and beneficial for forensic, population, genetic, and spermatogenesis-related studies  (日)    [継承]
副題 (任意):
要約 (任意): (英) A recently developed microsatellite marker on the Y chromosome, Yfm1, which was originally cloned from a cosmid clone mapped near the DAZ (Deleted in AZoospermia) genes, was used to classify Y chromosomes using an automatic sequencer. Yfm1 could detect multicopies on Y chromosomes in a single polymerase chain reaction, showing four main classes, A, A*, B, and C, according to the number of copies and peak patterns. Compound haplotype analysis of the Y chromosome using the Yfm1 marker with three other biallelic markers on the Y chromosome, SRY, DXYS5Y, and YAP, resulted in nine different haplotypes among different populations, including Japanese. Haplotype II (defined by YAP insertion) observed in the Japanese population was consistently associated with Yfm1 class A or A*, which showed the lowest number of copies of Yfm1. Haplotypes III and IV were consistently associated with Yfm1 class B. On the other hand, haplotype I showed a variety of Yfm1 patterns that were dubbed class C when not appropriately classified as A, A*, or B. These relationships among Yfm1 microsatellite and Y-specific biallelic markers could supply useful population genetic information. Moreover, because we have already shown that men with haplotype II have significantly lower spermatogenic ability than those with other haplotypes, Yfm1 class A or A* with the least number of copies may be related to the haplotype II-specific structure of the Y chromosome, such as deletion of DAZ or DAZ repeats, reflecting the lower spermatogenic abilities of Japanese haplotype II men. Thus, Yfm1 represents a very useful marker for analysis of genetic structure in different populations and studies on Y chromosome lineage-specific genotype-phenotype correlations.  (日)    [継承]
キーワード (推奨): 1. (英) Alleles (日) (読) [継承]
2. (英) Forensic Medicine (日) (読) [継承]
3. (英) Gene Dosage (日) (読) [継承]
4. (英) Genetic Markers (日) (読) [継承]
5. (英) Genetic Variation (日) (読) [継承]
6. (英) Genetics, Population (日) (読) [継承]
7. (英) Genotype (日) (読) [継承]
8. (英) Haplotypes (日) (読) [継承]
9. (英) Humans (日) (読) [継承]
10. (英) Male (日) (読) [継承]
11. (英) Microsatellite Repeats (日) (読) [継承]
12. (英) Phenotype (日) (読) [継承]
13. (英) Polymerase Chain Reaction (日) (読) [継承]
14. (英) Polymorphism, Genetic (日) (読) [継承]
15. (英) RNA-Binding Proteins (日) (読) [継承]
16. (英) Seminal Plasma Proteins (日) (読) [継承]
17. (英) Spermatogenesis (日) (読) [継承]
18.Y染色体 (Y chromosome) [継承]
発行所 (推奨):
誌名 (必須): Journal of Human Genetics (日本人類遺伝学会)
(pISSN: 1434-5161, eISSN: 1435-232X)

ISSN (任意): 1434-5161
ISSN: 1434-5161 (pISSN: 1434-5161, eISSN: 1435-232X)
Title: Journal of human genetics
Title(ISO): J Hum Genet
Publisher: Springer Science+Business Media
 (NLM Catalog  (医中誌Web  (Scopus  (CrossRef (Scopus information is found. [need login])
[継承]
[継承]
(必須): 47 [継承]
(必須): 10 [継承]
(必須): 523 528 [継承]
都市 (任意):
年月日 (必須): 西暦 2002年 10月 初日 (平成 14年 10月 初日) [継承]
URL (任意):
DOI (任意): 10.1007/s100380200078    (→Scopusで検索) [継承]
PMID (任意): 12376741    (→Scopusで検索) [継承]
NAID (任意):
WOS (任意):
Scopus (任意):
評価値 (任意):
被引用数 (任意):
指導教員 (推奨):
備考 (任意): 1.(英) Article.Affiliation: Department of Human Genetics and Public Health, Graduate School of Proteomics, Faculty of Medicine, The University of Tokushima, Japan.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Ashraf A. Ewis, Juwon W. Lee, Yoko Kuroki, Toshikatsu Shinka and Yutaka Nakahori : Yfm1, a multicopy marker specific for the Y chromosome and beneficial for forensic, population, genetic, and spermatogenesis-related studies, Journal of Human Genetics, Vol.47, No.10, 523-528, 2002.
欧文冊子 ● Ashraf A. Ewis, Juwon W. Lee, Yoko Kuroki, Toshikatsu Shinka and Yutaka Nakahori : Yfm1, a multicopy marker specific for the Y chromosome and beneficial for forensic, population, genetic, and spermatogenesis-related studies, Journal of Human Genetics, Vol.47, No.10, 523-528, 2002.

関連情報

Number of session users = 2, LA = 0.29, Max(EID) = 372535, Max(EOID) = 996375.