『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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登録内容 (EID=94667)

EID=94667EID:94667, Map:0, LastModified:2014年4月11日(金) 09:41:05, Operator:[松井 栄里], Avail:TRUE, Censor:0, Owner:[山田 博胤], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨): Peer Review [継承]
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨): 1.徳島大学.病院.診療科.内科 (2003年10月1日〜) [継承]
著者 (必須): 1. (英) Onose Yukiko (日) 小野瀬 由紀子 (読) おのせ ゆきこ
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[継承]
2. (英) Oki Takashi (日) 大木 崇 (読) おおき たかし
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3.山田 博胤 ([徳島大学.大学院医歯薬学研究部.医学域.連携研究部門(医学域).寄附講座系(医学域).地域循環器内科学])
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[継承]
4. (英) Manabe Kazuyo (日) 真鍋 和代 (読) まなべ かずよ
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[継承]
5. (英) Kageji Yoshimi (日) (読)
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[継承]
6. (英) Matsuoka Masako (日) (読)
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[継承]
7. (英) Yamamoto Takashi (日) (読)
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8.田畑 智継
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9.若槻 哲三 ([徳島大学.大学院医歯薬学研究部.医学域.先端医学教育研究プロジェクト]/[徳島大学.大学院医歯薬学研究部.医学域.医科学部門.内科系.循環器内科学]/[徳島大学.病院.診療科.内科.循環器内科])
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10.伊東 進
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題名 (必須): (英) Effect of cilnidipine on left ventricular diastolic function in hypertensive patients as assessed by pulsed Doppler echocardiography and pulsed tissue Doppler imaging.  (日)    [継承]
副題 (任意):
要約 (任意): (英) The purpose of the present study was to examine the mechanisms of improvement in left ventricular (LV) diastolic function in hypertensive patients treated with cilnidipine, a new and unique calcium antagonist that has both L-type and N-type voltage-dependent calcium channel blocking actions, using pulsed Doppler echocardiography and pulsed tissue Doppler imaging. The study comprised 35 untreated patients with essential hypertension (19 men and 16 women; mean age 65+/-10 years). The peak early diastolic and atrial systolic transmitral flow velocities (E and A, respectively) and their ratio (E/A), and the peak early diastolic and atrial systolic motion velocities (Ew and Aw, respectively) of the LV posterior wall and their ratio (Ew/Aw) were determined in all patients before and after 1, 3 and 6 months on cilnidipine (10 mg/day). One month: Systolic and diastolic blood pressures were significantly decreased. E and E/A were significantly increased, whereas there were no significant changes in Ew and Ew/Aw. Three months: Ew and Ew/Aw were significantly increased compared to those before and 1 month after cilnidipine. Six months: E and E/A were significantly increased compared with before and 3 months after cilnidipine, and Ew and Ew/Aw were significantly increased compared with before cilnidipine. Moreover, the LV mass index was significantly decreased compared to that before cilnidipine. In summary, changes in LV diastolic performance in patients with essential hypertension following cilnidipine treatment were biphasic with an initial increase in early diastolic transmitral flow velocity and a later increase in early diastolic LV wall motion velocity. The initial and later changes can be related to an acute change in afterload and a later improvement in LV relaxation.  (日)    [継承]
キーワード (推奨): 1. (英) Aged (日) (読) [継承]
2. (英) Antihypertensive Agents (日) (読) [継承]
3. (英) Blood Pressure (日) (読) [継承]
4. (英) Calcium Channel Blockers (日) (読) [継承]
5. (英) Calcium Channels, L-Type (日) (読) [継承]
6. (英) Calcium Channels, N-Type (日) (読) [継承]
7. (英) Diastole (日) (読) [継承]
8. (英) Dihydropyridines (日) (読) [継承]
9. (英) Echocardiography, Doppler, Pulsed (日) (読) [継承]
10. (英) Female (日) (読) [継承]
11. (英) Humans (日) (読) [継承]
12. (英) Hypertension (日) (読) [継承]
13. (英) Hypertrophy, Left Ventricular (日) (読) [継承]
14. (英) Male (日) (読) [継承]
15. (英) Middle Aged (日) (読) [継承]
16. (英) Systole (日) (読) [継承]
17. (英) Treatment Outcome (日) (読) [継承]
18. (英) Ventricular Dysfunction, Left (日) (読) [継承]
19. (英) Ventricular Function, Left (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Japanese Circulation Journal ([社団法人 日本循環器学会])
(pISSN: 0047-1828, eISSN: 1347-4839)

ISSN (任意): 0047-1828
ISSN: 0047-1828 (pISSN: 0047-1828, eISSN: 1347-4839)
Title: Japanese circulation journal
Title(ISO): Jpn Circ J
Supplier: 社団法人日本循環器学会
Publisher: Japanese Circulation Society/Nihon Junkanki Gakkai
 (NLM Catalog  (Webcat Plus  (Webcat Plus  (医中誌Web  (医中誌Web  (J-STAGE  (J-STAGE  (Scopus  (CrossRef (Scopus information is found. [need login])
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年月日 (必須): 西暦 2001年 4月 初日 (平成 13年 4月 初日) [継承]
URL (任意):
DOI (任意): 10.1253/jcj.65.305    (→Scopusで検索) [継承]
PMID (任意): 11316128    (→Scopusで検索) [継承]
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WOS (任意): 000167768600014 [継承]
Scopus (任意): 2-s2.0-0035045829 [継承]
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備考 (任意): 1.(英) Article.PublicationTypeList.PublicationType: Clinical Trial  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]

標準的な表示

和文冊子 ● Yukiko Onose, Takashi Oki, Hirotsugu Yamada, Kazuyo Manabe, Yoshimi Kageji, Masako Matsuoka, Takashi Yamamoto, Tomotsugu Tabata, Tetsuzo Wakatsuki and Susumu Ito : Effect of cilnidipine on left ventricular diastolic function in hypertensive patients as assessed by pulsed Doppler echocardiography and pulsed tissue Doppler imaging., Japanese Circulation Journal, Vol.65, No.4, 305-309, 2001.
欧文冊子 ● Yukiko Onose, Takashi Oki, Hirotsugu Yamada, Kazuyo Manabe, Yoshimi Kageji, Masako Matsuoka, Takashi Yamamoto, Tomotsugu Tabata, Tetsuzo Wakatsuki and Susumu Ito : Effect of cilnidipine on left ventricular diastolic function in hypertensive patients as assessed by pulsed Doppler echocardiography and pulsed tissue Doppler imaging., Japanese Circulation Journal, Vol.65, No.4, 305-309, 2001.

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