『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨): Peer Review [継承]
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨): 1.徳島大学.病院.診療科.内科 (2003年10月1日〜) [継承]
著者 (必須): 1. (英) Mishiro Yuichiro (日) 三代 裕一郎 (読) みしろ ゆういちろう
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2. (英) Oki Takashi (日) 大木 崇 (読) おおき たかし
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3.山田 博胤 ([徳島大学.大学院医歯薬学研究部.医学域.連携研究部門(医学域).寄附講座系(医学域).地域循環器内科学])
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4. (英) Onose Yukiko (日) 小野瀬 由紀子 (読) おのせ ゆきこ
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5. (英) Matsuoka Masako (日) (読)
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6.田畑 智継
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7.若槻 哲三 ([徳島大学.大学院医歯薬学研究部.医学域.先端医学教育研究プロジェクト]/[徳島大学.大学院医歯薬学研究部.医学域.医科学部門.内科系.循環器内科学]/[徳島大学.病院.診療科.内科.循環器内科])
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8.伊東 進
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題名 (必須): (英) Use of angiotensin II stress pulsed tissue Doppler imaging to evaluate regional left ventricular contractility in patients with hypertrophic cardiomyopathy.  (日)    [継承]
副題 (任意):
要約 (任意): (英) There is controversy concerning whether contract-ility in the nonhypertrophied region of the left ventricular (LV) wall is impaired or normal in patients with hypertrophic cardiomyopathy (HCM). Global LV systolic function decreases with increases in afterload in this disease. This study was performed to identify abnormalities in regional LV contractility along the long and short axes in the setting of HCM with the use of angiotensin II (AT-II) stress pulsed tissue Doppler imaging (PTDI). Angiotensin II was administered intravenously to patients with asymmetric septal hypertrophy (HCM group, n = 21) and age-matched normal volunteers (N group, n = 12). We then measured the percent LV fractional shortening (%FS) and end-systolic circumferential LV wall stress by M-mode echocardiography, LV ejection fraction (LVEF) by 2-dimensional echocardiography, and time-velocity integral (TVI) of LV outflow velocity by pulsed Doppler echocardiography. The peak first and second systolic LV wall motion velocities along the long (L-Sw(1) and L-Sw(2)) and short (S-Sw(1) and S-Sw(2)) axes were measured in the LV posterior wall and ventricular septum with the use of PTDI. The end-systolic circumferential LV wall stress at baseline was significantly lower in the HCM group. The L-Sw(1) and L-Sw(2) for the posterior wall were significantly lower in the HCM group, but the S-Sw(1) and S-Sw(2) for the posterior wall and ventricular septum were similar in the two groups. The %FS, LVEF, TVI, and systolic PTDI variables along both axes for the posterior wall decreased significantly, and end-systolic circumferential LV wall stress increased significantly at AT-II doses of 0.005 or 0.010 microg/kg per minute in the HCM group. No significant changes were found in either group in the systolic PTDI variables (except for L-Sw(1)) for the ventricular septum with AT-II infusion. Contractility along the long and short axes of the nonhypertrophied LV wall is easily impaired with increases in afterload in patients with HCM, resulting in a decrease in global LV systolic function. We found AT-II stress PTDI to be a safe and useful technique for evaluating the regional LV systolic function in this disease.  (日)    [継承]
キーワード (推奨): 1. (英) Analysis of Variance (日) (読) [継承]
2. (英) Angiotensin II (日) (読) [継承]
3. (英) Blood Flow Velocity (日) (読) [継承]
4. (英) Cardiomyopathy, Hypertrophic (日) (読) [継承]
5. (英) Case-Control Studies (日) (読) [継承]
6. (英) Echocardiography, Doppler, Pulsed (日) (読) [継承]
7. (英) Female (日) (読) [継承]
8. (英) Humans (日) (読) [継承]
9. (英) Infusions, Intravenous (日) (読) [継承]
10. (英) Male (日) (読) [継承]
11. (英) Middle Aged (日) (読) [継承]
12. (英) Myocardial Contraction (日) (読) [継承]
13. (英) Vasoconstrictor Agents (日) (読) [継承]
14. (英) Ventricular Dysfunction, Left (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Journal of the American Society of Echocardiography (American Society of Echocardiography)
(pISSN: 0894-7317, eISSN: 1097-6795)

ISSN (任意): 0894-7317
ISSN: 0894-7317 (pISSN: 0894-7317, eISSN: 1097-6795)
Title: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
Title(ISO): J Am Soc Echocardiogr
Publisher: C.V. Mosby Company
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(必須): 13 [継承]
(必須): 12 [継承]
(必須): 1065 1073 [継承]
都市 (任意):
年月日 (必須): 西暦 2000年 12月 初日 (平成 12年 12月 初日) [継承]
URL (任意):
DOI (任意): 10.1067/mje.2000.111010    (→Scopusで検索) [継承]
PMID (任意): 11119273    (→Scopusで検索) [継承]
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Scopus (任意): 2-s2.0-0034524367 [継承]
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備考 (任意): 1.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]

標準的な表示

和文冊子 ● Yuichiro Mishiro, Takashi Oki, Hirotsugu Yamada, Yukiko Onose, Masako Matsuoka, Tomotsugu Tabata, Tetsuzo Wakatsuki and Susumu Ito : Use of angiotensin II stress pulsed tissue Doppler imaging to evaluate regional left ventricular contractility in patients with hypertrophic cardiomyopathy., Journal of the American Society of Echocardiography, Vol.13, No.12, 1065-1073, 2000.
欧文冊子 ● Yuichiro Mishiro, Takashi Oki, Hirotsugu Yamada, Yukiko Onose, Masako Matsuoka, Tomotsugu Tabata, Tetsuzo Wakatsuki and Susumu Ito : Use of angiotensin II stress pulsed tissue Doppler imaging to evaluate regional left ventricular contractility in patients with hypertrophic cardiomyopathy., Journal of the American Society of Echocardiography, Vol.13, No.12, 1065-1073, 2000.

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