『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=93148EID:93148, Map:0, LastModified:2017年11月28日(火) 17:50:44, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[[医学部·歯学部附属病院長]/[徳島大学.病院]], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨): Peer Review [継承]
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨): 1.徳島大学.病院.診療科.小児·周産·女性科 (2003年10月1日〜) [継承]
著者 (必須): 1. (英) Kitamura Seiko (日) (読)
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2.横田 一郎
役割 (任意): 共著 [継承]
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3. (英) Hosoda Hiroshi (日) (読)
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4.小谷 裕美子 ([徳島大学.病院.診療科.小児·周産·女性科.小児科])
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学籍番号 (推奨):
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5.松田 純子
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6.内藤 悦雄
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7. (英) Ito Michinori (日) (読)
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8.寒川 賢治 (国立循環器病センター研究所)
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9.黒田 泰弘
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題名 (必須): (英) Ghrelin concentration in cord and neonatal blood -Relation to fetal growth and energy balance-  (日)    [継承]
副題 (任意):
要約 (任意): (英) To investigate the relationship between ghrelin and both fetal and neonatal growth parameters and energy balance, we measured plasma ghrelin concentrations in 54 cord blood samples (male, n = 34; female, n = 20; gestational age, 37.0-41.6 wk; birth weight, 2206-4326 g) and 47 neonatal blood samples (male, n = 27; female, n = 20; postnatal d 3-8). The plasma ghrelin concentrations in cord blood ranged from 110.6-446.1 pmol/liter (median, 206.7 pmol/liter), which were equal to or higher than those in normal weight adults. These values were inversely correlated with birth weight (r = -0.40; P = 0.002), birth length (r = -0.36; P = 0.007), placental weight (r = -0.35; P = 0.01), and IGF-I concentration (r = -0.49; P = 0.0002), but were not significantly correlated with the GH concentration (r = 0.22; P = 0.12). The ghrelin concentrations in small for gestational age newborn were significantly higher than those in appropriate for gestational age newborns (P = 0.0008). The ghrelin concentrations in the vein were significantly higher than those in the artery in 8 cord blood samples (P = 0.01), which suggests that the placenta is an important source of fetal ghrelin. In neonates, the ghrelin concentrations ranged from 133.0-481.7 pmol/liter (median, 268.3 pmol/liter), which were significantly higher than those in cord blood (P < 0.0001). These results suggest that ghrelin may contribute to fetal and neonatal growth.  (日)    [継承]
キーワード (推奨): 1. (英) HORMONE SECRETAGOGUE (日) (読) [継承]
2. (英) CIRCULATING GHRELIN (日) (読) [継承]
3. (英) ACYLATED PEPTIDE (日) (読) [継承]
4. (英) BIRTH-WEIGHT (日) (読) [継承]
5. (英) RAT-BRAIN (日) (読) [継承]
6. (英) IGF-II (日) (読) [継承]
7. (英) HUMANS (日) (読) [継承]
8. (英) LEPTIN (日) (読) [継承]
9. (英) EXPRESSION (日) (読) [継承]
10. (英) RECEPTOR (日) (読) [継承]
発行所 (推奨):
誌名 (必須): The Journal of Clinical Endocrinology and Metabolism ([The Endocrine Society])
(pISSN: 0021-972X, eISSN: 1945-7197)

ISSN (任意): 0021-972X
ISSN: 0021-972X (pISSN: 0021-972X, eISSN: 1945-7197)
Title: The Journal of clinical endocrinology and metabolism
Title(ISO): J Clin Endocrinol Metab
Publisher: Oxford University Press
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(必須): 88 [継承]
(必須): 11 [継承]
(必須): 5473 5477 [継承]
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年月日 (必須): 西暦 2003年 11月 初日 (平成 15年 11月 初日) [継承]
URL (任意):
DOI (任意): 10.1210/jc.2002-021350    (→Scopusで検索) [継承]
PMID (任意): 14602792    (→Scopusで検索) [継承]
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WOS (任意): 000186393900065 [継承]
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備考 (任意): 1.(英) Article.Affiliation: Department of Pediatrics, University of Tokushima School of Medicine, Tokushima 770-8503, Japan.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Seiko Kitamura, Ichiro Yokota, Hiroshi Hosoda, Yumiko Kotani, Junko Matsuda, Etsuo Naito, Michinori Ito, Kenji Kangawa and Yasuhiro Kuroda : Ghrelin concentration in cord and neonatal blood -Relation to fetal growth and energy balance-, The Journal of Clinical Endocrinology and Metabolism, Vol.88, No.11, 5473-5477, 2003.
欧文冊子 ● Seiko Kitamura, Ichiro Yokota, Hiroshi Hosoda, Yumiko Kotani, Junko Matsuda, Etsuo Naito, Michinori Ito, Kenji Kangawa and Yasuhiro Kuroda : Ghrelin concentration in cord and neonatal blood -Relation to fetal growth and energy balance-, The Journal of Clinical Endocrinology and Metabolism, Vol.88, No.11, 5473-5477, 2003.

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