『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=90349EID:90349, Map:0, LastModified:2014年4月11日(金) 09:29:44, Operator:[松井 栄里], Avail:TRUE, Censor:0, Owner:[勢井 宏義], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨): Peer Review [継承]
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1.森田 恭二
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[継承]
2. (英) Kuwada Aki (日) (読)
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[継承]
3.佐野 敦子
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4. (英) Sakata Mie (日) (読)
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5.勢井 宏義 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.生理系.統合生理学])
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6.森田 雄介
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題名 (必須): (英) Semi-quantitative RT-PCR analysis of environmental influence on P450scc and PNMT mRNA expression in rat adrenal glands  (日)    [継承]
副題 (任意):
要約 (任意): (英) Environmental influence on brain function, particularly spatial learning and memory, has been extensively investigated, but little is known about the influence of environmental conditions on the functions of peripheral organs. In the present study, the effects of different housing conditions on the steady-state levels of mRNAs encoding cholesterol side-chain cleavage enzyme (cytochrome P450scc) and phenylethanolamine N-methyltransferase (PNMT) in adrenal glands was examined to investigate the environmental influence on both adrenocortical and adrenomedullary functions. Behavioral changes of the animals housed in different conditions were first examined to assess the relevance of environmental manipulation used. In consistent with previous findings, housing of the animals in enriched conditions resulted in the significant reduction of spontaneous motor activity (locomotor activity and rearing) in comparison with housing in isolated conditions, thus indicating the relevance of housing conditions used in this work for investigating the environmental influence on adrenal function. Then, the effects of these housing conditions on P450scc and PNMT mRNA levels in adrenal glands were examined using semi-quantitative RT-PCR method. In comparison with the isolated group, the enriched group showed significantly higher levels of P450scc mRNA. In contrast, PNMT mRNA levels in the enriched group were significantly lower than those in the isolated group. These results propose the possibility that the environmental conditions may cause differential alterations in adrenocortical and adrenomedullary functions, although their possible association with behavioral changes still remains to be elucidated.  (日)    [継承]
キーワード (推奨): 1. (英) Adrenal Glands (日) (読) [継承]
2. (英) Animal Husbandry (日) (読) [継承]
3. (英) Animals (日) (読) [継承]
4. (英) Behavior, Animal (日) (読) [継承]
5. (英) Cholesterol Side-Chain Cleavage Enzyme (日) (読) [継承]
6. (英) DNA Primers (日) (読) [継承]
7. (英) Environment (日) (読) [継承]
8. (英) Male (日) (読) [継承]
9. (英) Motor Activity (日) (読) [継承]
10. (英) Phenylethanolamine N-Methyltransferase (日) (読) [継承]
11. (英) RNA, Messenger (日) (読) [継承]
12. (英) Rats (日) (読) [継承]
13. (英) Rats, Wistar (日) (読) [継承]
14. (英) Reverse Transcriptase Polymerase Chain Reaction (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Life Sciences ([Elsevier])
(pISSN: 0024-3205, eISSN: 1879-0631)

ISSN (任意): 0024-3205
ISSN: 0024-3205 (pISSN: 0024-3205, eISSN: 1879-0631)
Title: Life sciences
Title(ISO): Life Sci.
Publisher: Elsevier BV
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 70 [継承]
(必須): 1 [継承]
(必須): 73 80 [継承]
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年月日 (必須): 西暦 2001年 11月 21日 (平成 13年 11月 21日) [継承]
URL (任意): http://ci.nii.ac.jp/naid/80015140522/ [継承]
DOI (任意): 10.1016/S0024-3205(01)01368-6    (→Scopusで検索) [継承]
PMID (任意): 11764008    (→Scopusで検索) [継承]
NAID (任意): 80015140522 [継承]
WOS (任意): 000172351300007 [継承]
Scopus (任意): 2-s2.0-0035212269 [継承]
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備考 (任意): 1.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]

標準的な表示

和文冊子 ● Kyoji Morita, Aki Kuwada, Atsuko Sano, Mie Sakata, Hiroyoshi Sei and Yusuke Morita : Semi-quantitative RT-PCR analysis of environmental influence on P450scc and PNMT mRNA expression in rat adrenal glands, Life Sciences, Vol.70, No.1, 73-80, 2001.
欧文冊子 ● Kyoji Morita, Aki Kuwada, Atsuko Sano, Mie Sakata, Hiroyoshi Sei and Yusuke Morita : Semi-quantitative RT-PCR analysis of environmental influence on P450scc and PNMT mRNA expression in rat adrenal glands, Life Sciences, Vol.70, No.1, 73-80, 2001.

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