『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
ID: Pass:

登録内容 (EID=88387)

EID=88387EID:88387, Map:0, LastModified:2017年12月3日(日) 20:40:31, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[吉岡 昌美], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨): 1.徳島大学.歯学部.歯学科.基礎口腔科学講座.予防歯学 (予防歯科学講座) [継承]
著者 (必須): 1.吉岡 昌美
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
2. (英) Daniel Grenier (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
3.日野出 大輔 ([徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.口腔保健学系.口腔保健衛生学]/[徳島大学.歯学部.口腔保健学科.口腔保健基礎学講座])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
4.福井 誠 ([徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.口腔保健学系.口腔保健衛生学])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
5. (英) Denis Mayrand (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) Antigenic cross-reactivity and sequence homology between Actinobacillus actinomycetemcomitans GroEL protein and human fibronectin  (日)    [継承]
副題 (任意):
要約 (任意): (英) The immunologic cross-reactivity between human fibronectin and Actinobacillus actinomycetemcomitans GroEL was examined. Analyses by SDS-PAGE/Western immunoblotting and ELISA showed that a polyclonal antibody directed against the purified GroEL protein of A. actinomycetemcomitans, but not against the Escherichia coli GroEL, cross-reacts with human fibronectin. No antigenic cross-reactivity was observed between anti-A. actinomycetemcomitans GroEL antibody and type IV collagen, another important constituent of the basement membrane. A comparative analysis of the amino acid sequences of A. actinomycetemcomitans GroEL and human fibronectin revealed eight instances of four-amino acid sequence homology between the two proteins. Six of these tetrapeptide sequences were also shared with E. coli GroEL, suggesting that the remaining two tetrapeptides, GQLI (Glycine-Glutamine-Leucine-Isoleucine) and TGLE (Threonine-Glycine-Leucine-Glutamic acid), may be associated with the epitope that the anti-A. actinomycetemcomitans GroEL antibody specifically recognizes. Reactivity between TGLE, but not GQLI, with anti-A. actinomycetemcomitans GroEL antibody was confirmed by a biospecific interaction analysis using a biosensor technology. Although additional investigations are required, the observed phenomenon may lead to an autoimmune response and thus contribute to tissue destruction during periodontitis.  (日)    [継承]
キーワード (推奨): 1. (英) Actinobacillus actinomycetemcomitans (日) (読) [継承]
2. (英) fibronectin (日) (読) [継承]
3. (英) GroEL (日) (読) [継承]
4. (英) heat shock protein (日) (読) [継承]
5. (英) periodontitis (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Oral Microbiology and Immunology ([John Wiley & Sons, Inc.])
(pISSN: 0902-0055, eISSN: 1399-302X)

ISSN (任意): 0902-0055
ISSN: 0902-0055 (pISSN: 0902-0055, eISSN: 1399-302X)
Title: Oral microbiology and immunology
Title(ISO): Oral Microbiol. Immunol.
Publisher: Blackwell
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
[継承]
[継承]
(必須): 19 [継承]
(必須): 2 [継承]
(必須): 124 128 [継承]
都市 (任意):
年月日 (必須): 西暦 2004年 4月 初日 (平成 16年 4月 初日) [継承]
URL (任意):
DOI (任意): 10.1111/j.0902-0055.2003.00125.x    (→Scopusで検索) [継承]
PMID (任意): 14871354    (→Scopusで検索) [継承]
NAID (任意):
WOS (任意): 000188892400012 [継承]
Scopus (任意):
評価値 (任意):
被引用数 (任意):
指導教員 (推奨):
備考 (任意): 1.(英) Article.Affiliation: Department of Preventive Dentistry, School of Dentistry, University of Tokushima, Tokushima, Japan.  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Masami Yoshioka, Grenier Daniel, Daisuke Hinode, Makoto Fukui and Mayrand Denis : Antigenic cross-reactivity and sequence homology between Actinobacillus actinomycetemcomitans GroEL protein and human fibronectin, Oral Microbiology and Immunology, Vol.19, No.2, 124-128, 2004.
欧文冊子 ● Masami Yoshioka, Grenier Daniel, Daisuke Hinode, Makoto Fukui and Mayrand Denis : Antigenic cross-reactivity and sequence homology between Actinobacillus actinomycetemcomitans GroEL protein and human fibronectin, Oral Microbiology and Immunology, Vol.19, No.2, 124-128, 2004.

関連情報

Number of session users = 0, LA = 0.94, Max(EID) = 360730, Max(EOID) = 966223.