| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○招待 (推奨): |
| ○審査 (推奨): | □ | Peer Review
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| ○カテゴリ (推奨): |
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| ○学究種別 (推奨): |
| ○組織 (推奨): | 1. | 徳島大学.大学院ヘルスバイオサイエンス研究部.再生修復医歯学部門.顎口腔再建医学講座 (2004年4月1日〜)
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| 2. | 東北大学
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| ○著者 (必須): | 1. | (英) Takahashi I (日) (読)
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| 2. | (英) Nishimura M (日) (読)
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| 3. | (英) Onodera K (日) (読)
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| 4. | (英) Bae JW (日) (読)
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| 5. | (英) Mitani H (日) (読)
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| 6. | 岡崎 雅子
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| 7. | (英) Sasano Y (日) (読)
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| 8. | (英) Mitani H (日) (読)
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| ○題名 (必須): | □ | (英) Expression of MMP-8 and MMP-13 genes in the periodontal ligament during tooth movement in rats. (日)
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| ○要約 (任意): | □ | (英) Periodontal ligament tissue is remodeled on both the tension and compression sides of moving teeth during orthodontic tooth movement. The present study was designed to clarify the hypothesis that the expression of MMP-8 and MMP-13 mRNA is promoted during the remodeling of periodontal ligament tissue in orthodontic tooth movement. We used the in situ hybridization method and semi-quantitative reverse-transcription/polymerase chain-reaction analysis to elucidate the gene expression of MMP-8 and MMP-13 mRNA. Expression of MMP-8 and MMP-13 mRNA transiently increased on both the compression and tension sides during active tooth movement in vivo. The gene expression of MMP-8 and MMP-13 was induced by tension, while compression indirectly promoted the gene expression of MMP-8 and MMP-13 through soluble factors in vitro. Thus, we concluded that the expression of MMP-8 and MMP-13 is differentially regulated by tension and compression, and plays an important role in the remodeling of the periodontal ligament. (日)
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| ○キーワード (推奨): | 1. | (英) remodeling (日) (読)
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| 2. | コラーゲン (collagen)
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| 3. | (英) collagenase (日) (読)
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| 4. | (英) periodontal ligament (日) (読)
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| ○発行所 (推奨): |
| ○誌名 (必須): | □ | Journal of Dental Research ([国際歯科研究学会])
(pISSN: 0022-0345, eISSN: 1544-0591)
| ○ISSN (任意): | □ | 0022-0345
ISSN: 0022-0345
(pISSN: 0022-0345, eISSN: 1544-0591) Title: Journal of dental researchTitle(ISO): J Dent ResPublisher: SAGE Publications (NLM Catalog)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
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| ○巻 (必須): | □ | 82
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| ○号 (必須): | □ | 8
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| ○頁 (必須): | □ | 646 651
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2003年 8月 1日 (平成 15年 8月 1日)
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| ○URL (任意): | □ | http://ci.nii.ac.jp/naid/10015730796/
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| ○DOI (任意): | □ | 10.1177/154405910308200815 (→Scopusで検索)
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| ○PMID (任意): | □ | 12885852 (→Scopusで検索)
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| ○CRID (任意): | □ | 1573387449965926528
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| ○NAID : | □ | 10015730796
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| ○WOS (任意): | □ | 000184432400015
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| ○備考 (任意): | 1. | (英) Article.Affiliation: Division of Orthodontics and Dentofacial Orthopedics, Tohoku University Graduate School of Dentistry, Sendai, Japan. takahasi@mail.cc.tohoku.ac.jp (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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| 3. | (英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't (日)
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