| ○種別 (必須): | □ | 学術論文 (審査論文)
| [継承] |
| ○言語 (必須): | □ | 英語
| [継承] |
| ○招待 (推奨): |
| ○審査 (推奨): |
| ○カテゴリ (推奨): | □ | 研究
| [継承] |
| ○共著種別 (推奨): |
| ○学究種別 (推奨): |
| ○組織 (推奨): | 1. | 徳島大学.薬学部.製薬化学科 (〜2006年3月31日)
| [継承] |
| 2. | 徳島大学.ゲノム機能研究センター (〜2008年3月31日/->組織[徳島大学.疾患プロテオゲノム研究センター])
| [継承] |
| ○著者 (必須): | 1. | 山﨑 尚志 ([徳島大学.大学院医歯薬学研究部.薬学域.薬科学部門.創薬科学系.衛生薬学]/[徳島大学.薬学部.創製薬科学科.創薬学講座.衛生薬学]/[徳島大学.薬学研究科.創薬科学専攻])
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 2. | (英) Yamanaka Yasuhisa (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 3. | (英) Hashimoto Yoshiko (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 4. | (英) Hiramatsu Takayuki (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 5. | 篠原 康雄 ([徳島大学.先端酵素学研究所.基幹研究部門])
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 6. | 寺田 弘 ([東京理科大学])
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| ○題名 (必須): | □ | (英) The gene encoding muscle-type carnitine palmitoyltransferase I: comparison of the 5'-upstream region of human and rodent genes (日)
| [継承] |
| ○副題 (任意): |
| ○要約 (任意): | □ | (英) Muscle-type carnitine palmitoyltransferase I (M-CPTI) is the key enzyme for fatty acid beta-oxidation in heart and skeletal muscles and in adipose tissue. So far, M-CPTI mRNA has been detected in white adipocytes from epididymal fat pads of rats and humans, but not in mouse adipocytes. To characterize the gene expression of M-CPTI in mice, we isolated the genomic DNA encoding mouse M-CPTI and determined its transcription initiation site. As a result, the mouse M-CPTI gene seemed to have multiple initiation sites, as in the case of the rat and human genes. Furthermore, the conserved nucleotide sequence of the response element for peroxisome proliferators was shown to exist in the upstream of the mouse gene as in that of the rat and human genes. From these observations, we suggest that the anomalous expression of M-CPTI in mouse adipocytes reported previously may be regulated by factors other than peroxisome proliferators. Previously, we reported that there were transcripts containing regions of both CK/EK-beta and M-CPTI genes in humans. In this study, we found that such transcripts also exist in rodents and that the amounts of the transcripts containing regions of both of these genes did not depend on the expression level of CK/EK-beta. (日)
| [継承] |
| ○キーワード (推奨): | 1. | (英) Actins (日) (読)
| [継承] |
| 2. | (英) Adipocytes (日) (読)
| [継承] |
| 3. | (英) Adipose Tissue, Brown (日) (読)
| [継承] |
| 4. | (英) Amino Acid Sequence (日) (読)
| [継承] |
| 5. | (英) Animals (日) (読)
| [継承] |
| 6. | (英) Base Sequence (日) (読)
| [継承] |
| 7. | (英) Carnitine O-Palmitoyltransferase (日) (読)
| [継承] |
| 8. | (英) Choline Kinase (日) (読)
| [継承] |
| 9. | (英) DNA, Complementary (日) (読)
| [継承] |
| 10. | (英) Genes (日) (読)
| [継承] |
| 11. | (英) Humans (日) (読)
| [継承] |
| 12. | (英) Mice (日) (読)
| [継承] |
| 13. | (英) Molecular Sequence Data (日) (読)
| [継承] |
| 14. | (英) Muscles (日) (読)
| [継承] |
| 15. | (英) Phosphotransferases (Alcohol Group Acceptor) (日) (読)
| [継承] |
| 16. | (英) Rats (日) (読)
| [継承] |
| 17. | (英) Response Elements (日) (読)
| [継承] |
| 18. | (英) Reverse Transcriptase Polymerase Chain Reaction (日) (読)
| [継承] |
| 19. | (英) Transcription, Genetic (日) (読)
| [継承] |
| ○発行所 (推奨): |
| ○誌名 (必須): | □ | The Journal of Biochemistry ([日本生化学会])
(pISSN: 0021-924X, eISSN: 1756-2651)
| ○ISSN (任意): | □ | 0021-924X
ISSN: 0021-924X
(pISSN: 0021-924X, eISSN: 1756-2651) Title: Journal of biochemistryTitle(ISO): J BiochemSupplier: Oxford University PressPublisher: Oxford University Press (NLM Catalog)
(医中誌Web)
(J-STAGE)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
| [継承] |
| ○巻 (必須): | □ | 133
| [継承] |
| ○号 (必須): | □ | 4
| [継承] |
| ○頁 (必須): | □ | 523 532
| [継承] |
| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2003年 4月 初日 (平成 15年 4月 初日)
| [継承] |
| ○URL (任意): |
| ○DOI (任意): | □ | 10.1093/jb/mvg069 (→Scopusで検索)
| [継承] |
| ○PMID (任意): | □ | 12761301 (→Scopusで検索)
| [継承] |
| ○CRID (任意): |
| ○WOS (任意): |
| ○Scopus (任意): |
| ○評価値 (任意): |
| ○被引用数 (任意): |
| ○指導教員 (推奨): |
| ○備考 (任意): | 1. | (英) Article.Affiliation: Faculty of Pharmaceutical Sciences, University of Tokushima, Shomachi-1, Tokushima 770-8505. yamazaki@ph.tokushima-u.ac.jp (日)
| [継承] |
| 2. | (英) Article.DataBankList.DataBank.DataBankName: GENBANK (日)
| [継承] |
| 3. | (英) Article.DataBankList.DataBank.AccessionNumberList.AccessionNumber: AB010826 (日)
| [継承] |
| 4. | (英) Article.DataBankList.DataBank.AccessionNumberList.AccessionNumber: AB085661 (日)
| [継承] |
| 5. | (英) Article.PublicationTypeList.PublicationType: Comparative Study (日)
| [継承] |
| 6. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
| [継承] |
| 7. | (英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't (日)
| [継承] |