『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=72171EID:72171, Map:0, LastModified:2017年5月1日(月) 14:15:39, Operator:[三好 小文], Avail:TRUE, Censor:0, Owner:[堀口 大吾], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1. (英) Yu Xiong (日) (読)
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2.堀口 大吾 ([徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.基礎歯学系.分子医化学])
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3. (英) Shigesada Katsuya (日) 重定 勝哉 (読) しげさだ かつや
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4. (英) Egelman Edward (日) (読)
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題名 (必須): (英) Three-dimensional Reconstruction of Transcription Termination Factor rho: Orientation of the N-terminal Domain and Visualization of an RNA-binding Site  (日)    [継承]
副題 (任意):
要約 (任意): (英) The Escherichia coli rho transcription termination protein is a hexameric helicase, and is believed to function by separating an RNA-DNA hybrid. Unlike hexameric DNA helicases, where a single strand of DNA passes through the central channel, it has been proposed that the RNA wraps around the outside of the ring. We have generated a three-dimensional reconstruction of rho, and localized a tRNA molecule bound to the primary RNA-binding site to the outside of the ring. An atomic structure of the N-terminal domain of rho fits into our reconstruction uniquely, with the residues involved in RNA-binding on the outside of the ring. Although rho shares a common structural core with the F1-ATPase and other hexameric helicases, there has been a divergence in function due to rho's N-terminal domain, which has no homology to other helicases.  (日)    [継承]
キーワード (推奨): 1. (英) Binding Sites (日) (読) [継承]
2. (英) Escherichia coli (日) (読) [継承]
3. (英) Microscopy, Electron (日) (読) [継承]
4. (英) Models, Biological (日) (読) [継承]
5. (英) Models, Molecular (日) (読) [継承]
6. (英) Protein Structure, Quaternary (日) (読) [継承]
7. (英) Protein Structure, Secondary (日) (読) [継承]
8. (英) Proton-Translocating ATPases (日) (読) [継承]
9. (英) RNA, Bacterial (日) (読) [継承]
10. (英) RNA, Transfer (日) (読) [継承]
11. (英) RNA-Binding Proteins (日) (読) [継承]
12. (英) Rho Factor (日) (読) [継承]
13. (英) Transcription, Genetic (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Journal of Molecular Biology (Elsevier Ltd.)
(pISSN: 0022-2836, eISSN: 1089-8638)

ISSN (任意): 0022-2836
ISSN: 0022-2836 (pISSN: 0022-2836, eISSN: 1089-8638)
Title: Journal of molecular biology
Title(ISO): J. Mol. Biol.
Publisher: Elsevier Inc.
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 299 [継承]
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(必須): 1279 1287 [継承]
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年月日 (必須): 西暦 2000年 6月 23日 (平成 12年 6月 23日) [継承]
URL (任意):
DOI (任意): 10.1006/jmbi.2000.3810    (→Scopusで検索) [継承]
PMID (任意): 10873452    (→Scopusで検索) [継承]
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Scopus (任意): 2-s2.0-0034705329 [継承]
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備考 (任意): 1.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Research Support, U.S. Gov't, P.H.S.  (日)    [継承]

標準的な表示

和文冊子 ● Xiong Yu, Taigo Horiguchi, Katsuya Shigesada and Edward Egelman : Three-dimensional Reconstruction of Transcription Termination Factor rho: Orientation of the N-terminal Domain and Visualization of an RNA-binding Site, Journal of Molecular Biology, Vol.299, No.5, 1279-1287, 2000.
欧文冊子 ● Xiong Yu, Taigo Horiguchi, Katsuya Shigesada and Edward Egelman : Three-dimensional Reconstruction of Transcription Termination Factor rho: Orientation of the N-terminal Domain and Visualization of an RNA-binding Site, Journal of Molecular Biology, Vol.299, No.5, 1279-1287, 2000.

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