| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○招待 (推奨): |
| ○審査 (推奨): | □ | Peer Review
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| ○カテゴリ (推奨): | □ | 研究
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| ○共著種別 (推奨): |
| ○学究種別 (推奨): |
| ○組織 (推奨): | 1. | 徳島大学.大学院ヘルスバイオサイエンス研究部.生体システム栄養科学部門.摂食機能制御学講座 (2004年4月1日〜2015年3月31日)
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| ○著者 (必須): | 1. | (英) Muraki Yukoh (日) (読)
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| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
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| 2. | (英) Yoshioka Chihiro (日) (読)
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| 3. | (英) Tateishi Akira (日) (読)
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| 4. | (英) Fukuda Jinichi (日) (読)
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| 5. | 羽地 達次
| ○役割 (任意): | □ | 共著
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| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
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| 6. | (英) Kobayashi Nobuyuki (日) (読)
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| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
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| ○題名 (必須): | □ | (英) Localization of Fas antigen in oral squamous cell carcinoma. (日)
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| ○副題 (任意): |
| ○要約 (任意): | □ | (英) Fas antigen is a cell-surface protein that transduces an apoptotic signal from the cell surface into the cytoplasm. The localization of Fas antigen in human oral squamous cell carcinoma (SCC) was examined by immunohistochemistry using a monospecific polyclonal antibody with a high titre. This antibody, designated as Fas D, was raised against a synthetic polypeptide segment corresponding to a specific extracellular domain of human Fas antigen (aa 104-114). Thirty-eight specimens of oral SCCs were stained with Fas D antibody and 26 (68%) reacted intensely. The specimens were graded as 'well', 'moderately', or 'poorly differentiated', according to the histopathological criteria. Out of 24 cases of the well differentiated tumours examined, 22 had reacted to Fas staining. The tumour cells formed nests that encompassed keratin pearls; staining was confined to cytoplasmic granules of peripheral cells. Among the moderately differentiated tumours, 4 out of 11 cases had reacted to Fas staining. No Fas-positive cells were observed in the poorly differentiated tumours, but only three specimens were examined. The expression of Fas antigen seems to be related to the degree of tumour differentiation. (日)
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| ○キーワード (推奨): | 1. | (英) Aged (日) (読)
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| 2. | (英) Antibodies (日) (読)
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| 3. | (英) Antigens, CD95 (日) (読)
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| 4. | アポトーシス (apoptosis)
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| 5. | (英) Carcinoma, Squamous Cell (日) (読)
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| 6. | 細胞分化 (cell differentiation)
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| 7. | (英) Cell Membrane (日) (読)
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| 8. | (英) Coloring Agents (日) (読)
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| 9. | (英) Cytoplasm (日) (読)
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| 10. | (英) Cytoplasmic Granules (日) (読)
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| 11. | (英) Gene Expression Regulation, Neoplastic (日) (読)
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| 12. | (英) Humans (日) (読)
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| 13. | (英) Immunoenzyme Techniques (日) (読)
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| 14. | (英) Immunoglobulin G (日) (読)
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| 15. | 免疫組織化学 (immunohistochemistry)
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| 16. | (英) Keratins (日) (読)
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| 17. | (英) Middle Aged (日) (読)
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| 18. | (英) Mouth Neoplasms (日) (読)
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| ○発行所 (推奨): |
| ○誌名 (必須): | □ | The British Journal of Oral & Maxillofacial Surgery (British Association of Oral & Maxillofacial Surgeons)
(pISSN: 0266-4356, eISSN: 1532-1940)
| ○ISSN (任意): | □ | 0266-4356
ISSN: 0266-4356
(pISSN: 0266-4356, eISSN: 1532-1940) Title: The British journal of oral & maxillofacial surgeryTitle(ISO): Br J Oral Maxillofac SurgPublisher: Churchill Livingstone (NLM Catalog)
(Scopus)
(CrossRef)
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| ○巻 (必須): | □ | 37
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| ○号 (必須): | □ | 1
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| ○頁 (必須): | □ | 37 40
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 1999年 1月 初日 (平成 11年 1月 初日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1054/bjom.1998.0298 (→Scopusで検索)
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| ○PMID (任意): | □ | 10203220 (→Scopusで検索)
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| ○CRID (任意): |
| ○WOS (任意): | □ | 000078759300009
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| ○Scopus (任意): | □ | 2-s2.0-0032969509
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| ○評価値 (任意): |
| ○被引用数 (任意): |
| ○指導教員 (推奨): |
| ○備考 (任意): | 1. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't (日)
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