『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=68342EID:68342, Map:0, LastModified:2017年6月6日(火) 14:40:12, Operator:[三好 小文], Avail:TRUE, Censor:0, Owner:[福井 清], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨): Peer Review [継承]
カテゴリ (推奨): 研究 [継承]
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学究種別 (推奨):
組織 (推奨): 1.分子酵素学研究センター (〜2007年3月31日/->組織[疾患酵素学研究センター]) [継承]
著者 (必須): 1. (英) Yuasa Chie (日) 湯浅 智恵 (読) ゆあさ ちえ
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2. (英) Miyoshi Osamu (日) (読)
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3.福井 清 ([徳島大学])
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4. (英) Oka Toshinori (日) (読)
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[継承]
題名 (必須): (英) Hyperlipemia and Early Pancreatic Injury Induced by Ethanol Intake in Rats  (日)    [継承]
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要約 (任意): (英) The pathogenesis of alcoholic pancreatitis is unknown, and even though hyperlipemia has been hypothesized to be a risk factor for alcoholic pancreatitis, no studies directly investigating whether there is a relationship between the two have ever been reported. Therefore, to determine if a relationship exists between hyperlipemia and alcoholic pancreatitis, especially the early stage of alcoholic pancreatic injury, we administered a regular liquid Lieber-DeCarli diet, with and without ethanol as 35% of total calories, to rats for 2 wk. Thereafter we measured their plasma lipid concentrations, pancreatic zymogen granule fragility, and plasma lipase activity and subsequently investigated the correlations between these parameters. Significant increases in plasma triglyceride, total cholesterol, phospholipid, nonesterified fatty acid, pancreatic zymogen granule fragility, and plasma lipase activity were observed in the ethanol liquid diet group, compared with the values of the control liquid diet group, and pancreatic zymogen granule fragility was correlated with plasma triglyceride (r=0.62), total cholesterol (r=0.77), phospholipid (r=0.76), nonesterified fatty acid concentrations (r=0.62), and lipase activity (r=0.63). These results show a possible relationship between hyperlipemia and the early stage of alcoholic pancreatic injury, and they may support the hypothesis that hyperlipemia contributes to the etiology of alcoholic pancreatitis.  (日)    [継承]
キーワード (推奨): 1.初期段階 (early stage) [継承]
2.エタノール摂取 (ethanol intake) [継承]
3.ラット (rat) [継承]
4.高脂血症 (hyperlipemia) [継承]
5.膵損傷 (pancreatic injury) [継承]
発行所 (推奨): 日本栄養·食糧学会および日本ビタミン学会 [継承]
誌名 (必須): Journal of Nutritional Science and Vitaminology ([日本栄養·食糧学会]/[日本ビタミン学会])
(pISSN: 0301-4800, eISSN: 1881-7742)

ISSN (任意): 0301-4800
ISSN: 0301-4800 (pISSN: 0301-4800, eISSN: 1881-7742)
Title: Journal of nutritional science and vitaminology
Title(ISO): J. Nutr. Sci. Vitaminol.
Supplier: 日本ビタミン学会
Publisher: Center for Academic Publications Japan
 (NLM Catalog  (Webcat Plus  (医中誌Web  (J-STAGE  (Scopus  (CrossRef (Scopus information is found. [need login])
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年月日 (必須): 西暦 2000年 1月 初日 (平成 12年 1月 初日) [継承]
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PMID (任意): 11227801    (→Scopusで検索) [継承]
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Scopus (任意): 2-s2.0-0034519163 [継承]
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備考 (任意): 1.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]

標準的な表示

和文冊子 ● Chie Yuasa, Osamu Miyoshi, Kiyoshi Fukui and Toshinori Oka : Hyperlipemia and Early Pancreatic Injury Induced by Ethanol Intake in Rats, Journal of Nutritional Science and Vitaminology, Vol.46, No.6, 297-301, 2000.
欧文冊子 ● Chie Yuasa, Osamu Miyoshi, Kiyoshi Fukui and Toshinori Oka : Hyperlipemia and Early Pancreatic Injury Induced by Ethanol Intake in Rats, Journal of Nutritional Science and Vitaminology, Vol.46, No.6, 297-301, 2000.

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