『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=402841EID:402841, Map:0, LastModified:2023年9月11日(月) 15:05:22, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[橋本 登], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨): Peer Review [継承]
カテゴリ (推奨): 研究 [継承]
共著種別 (推奨): 国内共著 (徳島大学内研究者と国内(学外)研究者との共同研究 (国外研究者を含まない)) [継承]
学究種別 (推奨):
組織 (推奨): 1.徳島大学.歯学部.歯学科.基礎口腔科学講座.組織再生制御学 [継承]
著者 (必須): 1. (英) Furukawa Koichi (日) (読)
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2. (英) Ohmi Yuhsuke (日) (読)
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[継承]
3. (英) Hamamura Kazunori (日) (読)
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[継承]
4. (英) Kondo Yuji (日) (読)
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[継承]
5. (英) Ohkawa Yuki (日) (読)
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[継承]
6. (英) Kaneko Kei (日) (読)
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[継承]
7.橋本 登 ([徳島大学.大学院医歯薬学研究部.歯学域.先端歯学教育研究プロジェクト]/[徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.基礎歯学系.組織再生制御学])
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[継承]
8. (英) Yesmin Farhana (日) (読)
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[継承]
9. (英) Bhuiyan H. Robiul (日) (読)
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[継承]
10. (英) Tajima Orie (日) (読)
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[継承]
11. (英) Furukawa Keiko (日) (読)
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[継承]
題名 (必須): (英) Signaling domains of cancer-associated glycolipids.  (日)    [継承]
副題 (任意):
要約 (任意): (英) Immunotherapy of malignant cancers is now becoming one of representative approaches to overcome cancers. To construct strategies for immunotherapy, presence of tumor-specific antigens should be a major promise. A number of cancer specific- or cancer-associated antigens have been reported based on various experimental sets and various animal systems. The most reasonable strategy to define tumor-specific antigens might be "autologous typing" performed by Old's group, proposing three classes of tumor-antigens recognized by host immune systems of cancer patients. Namely, class 1, individual antigens that is present only in the patient's sample analyzed; class 2, shared antigens that can be found only in some group of cancers in some patients, but not in normal cells and tissues; class 3, universal antigens that are present in some cancers but also in normal cells and tissues with different densities. Sen Hakomori reported there were novel carbohydrates in cancers that could not be detected in normal cells mainly by biochemical approaches. Consequently, many of class 2 cancer-specific antigens have been revealed to be carbohydrate antigens, and been used for cancer diagnosis and treatment. Not only as cancer markers, but roles of those cancer-associated carbohydrates have also been recognized as functional molecules in cancer cells. In particular, roles of complex carbohydrates in the regulation of cell signaling on the cell surface microdomains, glycolipid-enriched microdomain (GEM)/rafts have been reported by Hakomori and many other researchers including us. The processes and present status of these studies on cancer-associated glycolipids were summarized.  (日)    [継承]
キーワード (推奨): 1. (英) Animals (日) (読) [継承]
2. (英) Antigens, Tumor-Associated, Carbohydrate (日) (読) [継承]
3. (英) Biomarkers, Tumor (日) (読) [継承]
4. (英) Glycolipids (日) (読) [継承]
5. (英) Humans (日) (読) [継承]
6. (英) Neoplasms (日) (読) [継承]
7. (英) Signal Transduction (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Glycoconjugate Journal (International Glycoconjugate Organization)
(pISSN: 0282-0080, eISSN: 1573-4986)

ISSN (任意): 1573-4986
ISSN: 0282-0080 (pISSN: 0282-0080, eISSN: 1573-4986)
Title: Glycoconjugate journal
Title(ISO): Glycoconj J
Supplier: Kluwer Online
Publisher: Springer
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 145 155 [継承]
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年月日 (必須): 西暦 2022年 3月 22日 (令和 4年 3月 22日) [継承]
URL (任意):
DOI (任意): 10.1007/s10719-022-10051-1    (→Scopusで検索) [継承]
PMID (任意): 35315508    (→Scopusで検索) [継承]
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備考 (任意): 1.(英) Article.ELocationID: 10.1007/s10719-022-10051-1  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Review  (日)    [継承]
4.(英) Article.PublicationTypeList.PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]
5.(英) KeywordList.Keyword: Cancer. Tumor antigen. Carbohydrate. Glycolipid. Antibody. Raft  (日)    [継承]

標準的な表示

和文冊子 ● Koichi Furukawa, Yuhsuke Ohmi, Kazunori Hamamura, Yuji Kondo, Yuki Ohkawa, Kei Kaneko, Noboru Hashimoto, Farhana Yesmin, Robiul H. Bhuiyan, Orie Tajima and Keiko Furukawa : Signaling domains of cancer-associated glycolipids., Glycoconjugate Journal, Vol.39, No.2, 145-155, 2022.
欧文冊子 ● Koichi Furukawa, Yuhsuke Ohmi, Kazunori Hamamura, Yuji Kondo, Yuki Ohkawa, Kei Kaneko, Noboru Hashimoto, Farhana Yesmin, Robiul H. Bhuiyan, Orie Tajima and Keiko Furukawa : Signaling domains of cancer-associated glycolipids., Glycoconjugate Journal, Vol.39, No.2, 145-155, 2022.

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