『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=381984EID:381984, Map:0, LastModified:2021年9月15日(水) 10:47:48, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[堤 理恵], Read:継承, Write:継承, Delete:継承.
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言語 (必須): 英語 [継承]
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著者 (必須): 1. (英) Fukushima Sachiyo (日) (読)
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2. (英) Nakanishi Nobuto (日) (読)
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3. (英) Fujioka Kazumichi (日) (読)
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4. (英) Suga Kenichi (日) (読)
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5. (英) Shirakawa Taku (日) (読)
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6. (英) Osawa Kayo (日) (読)
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7. (英) Hara Kanako (日) (読)
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8.堤 理恵 ([徳島大学.大学院医歯薬学研究部.医学域.栄養科学部門.医科栄養学系.代謝栄養学])
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9. (英) Urushihara Maki (日) (読)
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10. (英) Nakagawa Ryuji (日) (読)
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11. (英) Awano Hiroyuki (日) (読)
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12. (英) Oto Jun (日) (読)
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13. (英) Sakaue Hiroshi (日) (読)
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14. (英) Iijima Kazumoto (日) (読)
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15. (英) Matsuo Masafumi (日) (読)
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題名 (必須): (英) Assessment of catabolic state in infants with the use of urinary titin N-fragment.  (日)    [継承]
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要約 (任意): (英) Urinary titin N-fragment levels have been used to assess the catabolic state, and we used this biomarker to evaluate the catabolic state of infants. We retrospectively measured urinary titin N-fragment levels of urinary samples. The primary outcome was its changes according to postmenstrual age. The secondary outcomes included differences between gestational age, longitudinal change after birth, influence on growth, and relationship with blood tests. This study included 219 patients with 414 measurements. Urinary titin N-fragment exponentially declined with postmenstrual age. These values were 12.5 (7.1-19.6), 8.1 (5.1-13.0), 12.8 (6.0-21.3), 26.4 (16.4-52.0), and 81.9 (63.3-106.4) pmol/mg creatinine in full, late, moderate, very, and extremely preterm infants, respectively (p < 0.01). After birth, urinary levels of titin N-fragment exponentially declined, and the maximum level within a week was associated with the time to return to birth weight in preterm infants (ϱ = 0.39, p < 0.01). This was correlated with creatine kinase in full-term infants (ϱ = 0.58, p < 0.01) and with blood urea nitrogen in preterm infants (ϱ = 0.50, p < 0.01). The catabolic state was increased during the early course of the postmenstrual age and early preterm infants. Catabolic state in infants, especially in preterm infants, was expected to be increased, but no study has clearly verified this. In this retrospective study of 219 patients with 414 urinary titin measurements, the catabolic state was exponentially elevated during the early postmenstrual age. The use of the urinary titin N-fragment clarified catabolic state was prominently increased in very and extremely preterm infants.  (日)    [継承]
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誌名 (必須): Pediatric Research (American Pediatric Society/Society for Pediatric Research (U.S.))
(pISSN: 0031-3998, eISSN: 1530-0447)

ISSN (任意): 1530-0447
ISSN: 0031-3998 (pISSN: 0031-3998, eISSN: 1530-0447)
Title: Pediatric research
Title(ISO): Pediatr Res
Publisher: Springer Nature
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
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年月日 (必須): 西暦 2021年 7月 17日 (令和 3年 7月 17日) [継承]
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DOI (任意): 10.1038/s41390-021-01658-5    (→Scopusで検索) [継承]
PMID (任意): 34274960    (→Scopusで検索) [継承]
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備考 (任意): 1.(英) Article.ELocationID: 10.1038/s41390-021-01658-5  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]

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和文冊子 ● (種別) : Sachiyo Fukushima, Nobuto Nakanishi, Kazumichi Fujioka, Kenichi Suga, Taku Shirakawa, Kayo Osawa, Kanako Hara, Rie Tsutsumi, Maki Urushihara, Ryuji Nakagawa, Hiroyuki Awano, Jun Oto, Hiroshi Sakaue, Kazumoto Iijima and Masafumi Matsuo : Assessment of catabolic state in infants with the use of urinary titin N-fragment., Pediatric Research, (巻), (号), (頁), (発行所), (都市), July 2021.
欧文冊子 ● (種別) : Sachiyo Fukushima, Nobuto Nakanishi, Kazumichi Fujioka, Kenichi Suga, Taku Shirakawa, Kayo Osawa, Kanako Hara, Rie Tsutsumi, Maki Urushihara, Ryuji Nakagawa, Hiroyuki Awano, Jun Oto, Hiroshi Sakaue, Kazumoto Iijima and Masafumi Matsuo : Assessment of catabolic state in infants with the use of urinary titin N-fragment., Pediatric Research, (巻), (号), (頁), (発行所), (都市), July 2021.

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