| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○カテゴリ (推奨): |
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| ○組織 (推奨): |
| ○著者 (必須): | 1. | (英) Mizuma Hiroshi (日) (読)
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| 2. | (英) Tanaka Masaaki (日) (読)
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| 3. | (英) Nozaki Satoshi (日) (読)
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| 4. | (英) Mizuno Kei (日) (読)
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| 5. | 田原 強 ([徳島大学.先端研究推進センター.バイオイメージング研究部門])
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| 6. | (英) Ataka Suzuka (日) (読)
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| 7. | (英) Sugino Tomohiro (日) (読)
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| 8. | (英) Shirai Tomoko (日) (読)
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| 9. | (英) Kajimoto Yoshitaka (日) (読)
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| 10. | (英) Kuratsune Hirohiko (日) (読)
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| 11. | (英) Kajimoto Osami (日) (読)
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| 12. | (英) Watanabe Yasuyoshi (日) (読)
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| ○題名 (必須): | □ | (英) Daily oral administration of crocetin attenuates physical fatigue in human subjects. (日)
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| ○要約 (任意): | □ | (英) This study compared the effects of placebo with a carotenoid compound, crocetin, as well as an antioxidant, ascorbic acid, on physical fatigue in humans. In this double-blind, placebo-controlled, 3-way crossover study, 14 Japanese healthy volunteers (7 men and 7 women) were randomized to oral administration of crocetin (15 mg), ascorbic acid (3,000 mg), or placebo for 8 days. Subjects performed workload tests on a bicycle ergometer at fixed workloads for 120 minutes at 2 times (a total of 240 minutes) as a fatigue-inducing physical task. During the physical task, subjects performed nonworkload tests at maximum velocity (MV) of 10 seconds at 30 minutes (30-minute test) after the start of the physical task and at 30 minutes before the end of the task (210-minute test). The change in MV from the 30- to the 210-minute test was significantly higher in men who received crocetin compared with men who received placebo (P < .05). This effect of crocetin was specific to males. Administration of ascorbic acid did not change in MV from the 30-minute to the 210-minute test on males or females. These results suggest that daily administration of crocetin may attenuate physical fatigue in men. (日)
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| ○キーワード (推奨): | 1. | (英) Administration, Oral (日) (読)
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| 2. | (英) Adult (日) (読)
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| 3. | (英) Antioxidants (日) (読)
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| 4. | (英) Ascorbic Acid (日) (読)
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| 5. | (英) Bicycling (日) (読)
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| 6. | (英) Carotenoids (日) (読)
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| 7. | (英) Double-Blind Method (日) (読)
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| 8. | (英) Drug Administration Schedule (日) (読)
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| 9. | (英) Exercise (日) (読)
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| 10. | (英) Exercise Test (日) (読)
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| 11. | (英) Fatigue (日) (読)
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| 12. | (英) Female (日) (読)
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| 13. | (英) Humans (日) (読)
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| 14. | (英) Male (日) (読)
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| 15. | (英) Middle Aged (日) (読)
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| 16. | (英) Physical Exertion (日) (読)
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| 17. | (英) Sex Factors (日) (読)
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| ○発行所 (推奨): |
| ○誌名 (必須): | □ | Nutrition Research ([Elsevier])
(pISSN: 0271-5317, eISSN: 1879-0739)
| ○ISSN (任意): | □ | 1879-0739
ISSN: 0271-5317
(pISSN: 0271-5317, eISSN: 1879-0739) Title: Nutrition research (New York, N.Y.)Title(ISO): Nutr ResPublisher: Elsevier Inc. (NLM Catalog)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
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| ○巻 (必須): | □ | 29
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| ○号 (必須): | □ | 3
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| ○頁 (必須): | □ | 145 150
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| ○年月日 (必須): | □ | 西暦 2009年 3月 初日 (平成 21年 3月 初日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1016/j.nutres.2009.02.003 (→Scopusで検索)
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| ○PMID (任意): | □ | 19358927 (→Scopusで検索)
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| ○備考 (任意): | 1. | (英) PublicationType: Comparative Study (日)
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| 2. | (英) PublicationType: Journal Article (日)
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| 3. | (英) PublicationType: Randomized Controlled Trial (日)
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| 4. | (英) PublicationType: Research Support, Non-U.S. Gov't (日)
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