| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○カテゴリ (推奨): |
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| ○学究種別 (推奨): |
| ○組織 (推奨): |
| ○著者 (必須): | 1. | 後藤 正和 ([徳島大学.大学院医歯薬学研究部.医学域.先端医学教育研究プロジェクト]/[徳島大学.大学院医歯薬学研究部.医学域.医科学部門.外科系.胸部・内分泌・腫瘍外科学])
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| 2. | (英) Shibahara Yukiko (日) (読)
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| 3. | (英) Baciu Cristina (日) (読)
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| 4. | (英) Allison Frances (日) (読)
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| 5. | (英) Yeung Jonathan C (日) (読)
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| 6. | (英) Darling Gail E (日) (読)
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| 7. | (英) Liu Mingyao (日) (読)
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| ○題名 (必須): | □ | (英) Prognostic Impact of CXCR7 and CXCL12 Expression in Patients with Esophageal Adenocarcinoma. (日)
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| ○副題 (任意): |
| ○要約 (任意): | □ | (英) High CXCR7 expression was associated with poor prognosis in patients with EAC, and high expression of CXCR7 with its ligand CXCL12 had a stronger association with prognosis. Further study of this potential biomarker using whole tissue samples and a larger sample size is warranted. (日) High CXCR7 expression was significantly associated with lymphatic invasion (present vs absent, P = 0.005) and higher number of lymph node metastases (pN0-1 vs pN2-3, P = 0.0014). Patients with high CXCR7 expression (n = 23) were associated with worse overall (OS) and disease-free survival (DFS) (P = 0.0221, P = 0.0090, respectively), and patients with high CXCL12 (n = 24) tended to have worse OS and DFS (P = 0.1091, P = 0.1477, respectively). High expression of both CXCR7 and CXCL12 was an independent prognostic factor for OS and DFS on multivariate analysis (HR = 0.3, 95% CI: 0.1-0.9, P = 0.0246, HR = 0.3, 95% CI: 0.1-0.8, P = 0.0134, respectively).
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| ○キーワード (推奨): | 1. | (英) Adenocarcinoma (日) (読)
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| 2. | (英) Chemokine CXCL12 (日) (読)
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| 3. | (英) Esophageal Neoplasms (日) (読)
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| 4. | (英) Humans (日) (読)
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| 5. | (英) Lymphatic Metastasis (日) (読)
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| 6. | (英) Prognosis (日) (読)
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| 7. | (英) Receptors, CXCR (日) (読)
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| 8. | (英) Receptors, CXCR4 (日) (読)
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| ○発行所 (推奨): |
| ○誌名 (必須): | □ | Annals of Surgical Oncology (Society of Surgical Oncology (U.S.))
(pISSN: 1068-9265, eISSN: 1534-4681)
| ○ISSN (任意): | □ | 1534-4681
ISSN: 1068-9265
(pISSN: 1068-9265, eISSN: 1534-4681) Title: Annals of surgical oncologyTitle(ISO): Ann Surg OncolSupplier: Springer Online Journal ArchivePublisher: Springer (NLM Catalog)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
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| ○巻 (必須): | □ | 28
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| ○号 (必須): | □ | 9
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| ○頁 (必須): | □ | 4943 4951
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2021年 3月 11日 (令和 3年 3月 11日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1245/s10434-021-09775-5 (→Scopusで検索)
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| ○PMID (任意): | □ | 33709176 (→Scopusで検索)
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| ○備考 (任意): | 1. | (英) PublicationType: Journal Article (日)
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