| ○種別 (必須): | □ | 学術論文 (審査論文)
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| ○言語 (必須): | □ | 英語
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| ○招待 (推奨): |
| ○審査 (推奨): | □ | Peer Review
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| ○カテゴリ (推奨): | □ | 研究
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| ○共著種別 (推奨): | □ | 学内共著 (徳島大学内研究者との共同研究 (学外研究者を含まない))
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| ○学究種別 (推奨): |
| ○組織 (推奨): |
| ○著者 (必須): | 1. | 山本 伸昭
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| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
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| 2. | 和泉 唯信 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.内科系.臨床神経科学]/[徳島大学.病院.診療科.内科.脳神経内科])
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| ○学籍番号 (推奨): |
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| 3. | 山本 雄貴 ([徳島大学.病院.診療科.内科.脳神経内科])
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| ○学籍番号 (推奨): |
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| 4. | (英) Kuroda K (日) 黒田 一駿 (読) くろだ かずたか
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| ○学籍番号 (推奨): | □ | ****
| [ユーザ] |
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| 5. | 山口 泉
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| 6. | 曽我部 周
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| 7. | 宮本 健志 ([徳島大学.大学院医歯薬学研究部.医学域.先端医学教育研究プロジェクト]/[徳島大学.大学院医歯薬学研究部.医学域.医科学部門.外科系.脳神経外科学])
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| ○学籍番号 (推奨): |
| [継承] |
| 8. | 島田 健司 ([徳島大学.病院.先端医科医療開発研究プロジェクト]/[徳島大学.病院.診療科.脳·神経·精神科.脳神経外科])
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| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 9. | 兼松 康久
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| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 10. | 森垣 龍馬 ([徳島大学.大学院医歯薬学研究部.医学域.共同研究講座.先端脳機能研究開発]/[徳島大学.病院.診療科.脳·神経·精神科.脳神経外科])
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| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 11. | 髙木 康志 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.外科系.脳神経外科学])
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| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| ○題名 (必須): | □ | (英) Factors associated with DWI-ASPECTS score in patients with acute ischemic stroke due to cerebral large vessel occlusion (日)
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| ○要約 (任意): | □ | (英) The Alberta Stroke Program Early CT score (ASPECTS) of patients with acute ischemic stroke at the time of admission varies. It is crucial to select appropriate methods of treatment, such as recombinant tissue-plasminogen activator, and/or endovascular thrombectomy. According to the recent guidelines, endovascular thrombectomy for patients with large vessel occlusion (LVO) and lesion of ischemic tissue that was not yet infarcted is effective. This result demonstrates the importance of patient selection based on neuroradiological imaging. However, there are many patients who are judged as ineligibility for recanalization therapy because of presence of large ischemic core, indicating unfavorable ASPECTS, at the time of admission. We investigated the factors associated with favorable diffusion-weighted image (DWI)-ASPECTS score at the time of admission. We studies patients with LVO within 24 h from onset who were admitted into our hospital. We divided them into two groups, with favorable DWI-ASPECTS (≥6), and unfavorable DWI-ASPECTS (<6) at the time of admission. We investigated factors associated with favorable DWI-ASPECTS by evaluation of our patients' severity of clinical symptom, etiology, and radiological findings. This study showed that mild white matter lesion (Fazekas scale ≤1), absence of internal carotid artery (ICA) occlusion and cardioembolic stroke were independent factor of favorable DWI-ASPECTS at the time of admission. (odds ratio 12.92, p < 0.001, odds ratio 0.31, p = 0.001, odds ratio 0.16, p = 0.001, respectively) CONCLUSIONS: Absence of severe white matter lesion, cardioembolic stroke, and ICA occlusion might be associated with favorable DWI-ASPECTS at the time of admission. (日)
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| ○キーワード (推奨): | 1. | (英) Aged (日) (読)
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| 2. | (英) Aged, 80 and over (日) (読)
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| 3. | (英) Brain Ischemia (日) (読)
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| 4. | (英) Cerebrovascular Disorders (日) (読)
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| 5. | (英) Diffusion Magnetic Resonance Imaging (日) (読)
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| 6. | (英) Female (日) (読)
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| 7. | (英) Humans (日) (読)
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| 8. | (英) Ischemic Stroke (日) (読)
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| 9. | (英) Male (日) (読)
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| 10. | (英) Middle Aged (日) (読)
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| 11. | (英) Patient Admission (日) (読)
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| 12. | (英) Prospective Studies (日) (読)
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| 13. | (英) Retrospective Studies (日) (読)
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| 14. | (英) Severity of Illness Index (日) (読)
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| ○発行所 (推奨): |
| ○誌名 (必須): | □ | Clinical Neurology and Neurosurgery (Nederlandse Vereniging van Neurochirurgen)
(pISSN: 0303-8467, eISSN: 1872-6968)
| ○ISSN (任意): | □ | 1872-6968
ISSN: 0303-8467
(pISSN: 0303-8467, eISSN: 1872-6968) Title: Clinical neurology and neurosurgeryTitle(ISO): Clin Neurol NeurosurgPublisher: Elsevier B.V. (NLM Catalog)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
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| ○巻 (必須): | □ | 199
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| ○号 (必須): | □ |
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| ○頁 (必須): | □ | 106316 106316
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| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2020年 10月 16日 (令和 2年 10月 16日)
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| ○URL (任意): |
| ○DOI (任意): | □ | 10.1016/j.clineuro.2020.106316 (→Scopusで検索)
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| ○PMID (任意): | □ | 33161217 (→Scopusで検索)
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| ○CRID (任意): |
| ○WOS (任意): |
| ○Scopus (任意): |
| ○評価値 (任意): |
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| ○指導教員 (推奨): |
| ○備考 (任意): | 1. | (英) Article.ELocationID: S0303-8467(20)30659-4 (日)
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| 2. | (英) Article.ELocationID: 10.1016/j.clineuro.2020.106316 (日)
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| 3. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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| 4. | (英) KeywordList.Keyword: Acute ischemic stroke (日)
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| 5. | (英) KeywordList.Keyword: DWI- ASPECTS (日)
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| 6. | (英) KeywordList.Keyword: Large vessel occlusion (日)
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| 7. | (英) KeywordList.Keyword: White matter lesion (日)
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