『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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登録内容 (EID=370996)

EID=370996EID:370996, Map:0, LastModified:2020年9月2日(水) 18:54:33, Operator:[橋本 登], Avail:TRUE, Censor:0, Owner:[橋本 登], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1. (英) Kurosawa Maiko (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
2. (英) Jeyasekharan Anand D (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
3. (英) Surmann Eva-Maria (日) (読)
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貢献度 (任意):
学籍番号 (推奨):
[継承]
4.橋本 登 ([徳島大学.大学院医歯薬学研究部.歯学域.先端歯学教育研究プロジェクト]/[徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.基礎歯学系.組織再生制御学])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
5. (英) Venkatraman Vignesh (日) (読)
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貢献度 (任意):
学籍番号 (推奨):
[継承]
6. (英) Kurosawa Gene (日) (読)
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貢献度 (任意):
学籍番号 (推奨):
[継承]
7. (英) Furukawa Koichi (日) (読)
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貢献度 (任意):
学籍番号 (推奨):
[継承]
8. (英) Venkitaraman Ashok R (日) (読)
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貢献度 (任意):
学籍番号 (推奨):
[継承]
9. (英) Kurosawa Yoshikazu (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) Expression of LY6D is induced at the surface of MCF10A cells by X-ray irradiation.  (日)    [継承]
副題 (任意):
要約 (任意): (英) In order to identify membrane proteins whose expression is induced by X-ray irradiation, we developed an antibody (Ab)-directed strategy using a phage Ab library. X-Ray-irradiated cells were screened with a phage Ab library in the presence of a large excess of polyclonal Abs prepared against membrane proteins that are commonly present at the surface of both X-ray-irradiated and nonirradiated cells. After isolation of Ab that bound only to X-ray-irradiated cells, the antigen was identified using MS. Using this approach, we found that expression of LY6D is induced in MCF10A cells by X-ray irradiation. The induction of LY6D expression is triggered through a pathway regulated by ATM, CHK2 and p53. This method is a new Ab-directed proteomic strategy for analysis of membrane proteins, and is applicable to various biological phenomena in situations in which both target molecule-expressing cells and nonexpressing cells are available.  (日)    [継承]
キーワード (推奨): 1. (英) Ataxia Telangiectasia Mutated Proteins (日) (読) [継承]
2. (英) Base Sequence (日) (読) [継承]
3. (英) Cell Adhesion Molecules (日) (読) [継承]
4. (英) Cell Cycle Proteins (日) (読) [継承]
5. (英) Cell Line, Tumor (日) (読) [継承]
6. (英) Checkpoint Kinase 2 (日) (読) [継承]
7. (英) DNA Primers (日) (読) [継承]
8. (英) DNA-Binding Proteins (日) (読) [継承]
9. (英) GPI-Linked Proteins (日) (読) [継承]
10. (英) Humans (日) (読) [継承]
11. (英) Mutagens (日) (読) [継承]
12. (英) Protein-Serine-Threonine Kinases (日) (読) [継承]
13. (英) Proto-Oncogene Proteins p21(ras) (日) (読) [継承]
14. (英) RNA, Small Interfering (日) (読) [継承]
15. (英) Real-Time Polymerase Chain Reaction (日) (読) [継承]
16. (英) Transcription, Genetic (日) (読) [継承]
17. (英) Tumor Suppressor Protein p53 (日) (読) [継承]
18. (英) Tumor Suppressor Proteins (日) (読) [継承]
19. (英) X-Rays (日) (読) [継承]
発行所 (推奨):
誌名 (必須): The FEBS Journal ([Federation of European Biochemical Societies])
(pISSN: 1742-464X, eISSN: 1742-4658)

ISSN (任意): 1742-4658
ISSN: 1742-464X (pISSN: 1742-464X, eISSN: 1742-4658)
Title: The FEBS journal
Title(ISO): FEBS J
Supplier: Federation of European Biochemical Societies
Publisher: Wiley Publishing
 (NLM Catalog  (Wiley  (Scopus  (CrossRef (Scopus information is found. [need login])
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(必須): 279 [継承]
(必須): 24 [継承]
(必須): 4479 4491 [継承]
都市 (任意):
年月日 (必須): 西暦 2012年 11月 22日 (平成 24年 11月 22日) [継承]
URL (任意):
DOI (任意): 10.1111/febs.12034    (→Scopusで検索) [継承]
PMID (任意): 23075424    (→Scopusで検索) [継承]
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備考 (任意): 1.(英) PublicationType: Journal Article  (日)    [継承]
2.(英) PublicationType: Research Support, Non-U.S. Gov't  (日)    [継承]

標準的な表示

和文冊子 ● Maiko Kurosawa, D Anand Jeyasekharan, Eva-Maria Surmann, Noboru Hashimoto, Vignesh Venkatraman, Gene Kurosawa, Koichi Furukawa, R Ashok Venkitaraman and Yoshikazu Kurosawa : Expression of LY6D is induced at the surface of MCF10A cells by X-ray irradiation., The FEBS Journal, Vol.279, No.24, 4479-4491, 2012.
欧文冊子 ● Maiko Kurosawa, D Anand Jeyasekharan, Eva-Maria Surmann, Noboru Hashimoto, Vignesh Venkatraman, Gene Kurosawa, Koichi Furukawa, R Ashok Venkitaraman and Yoshikazu Kurosawa : Expression of LY6D is induced at the surface of MCF10A cells by X-ray irradiation., The FEBS Journal, Vol.279, No.24, 4479-4491, 2012.

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