| ○種別 (必須): | □ | 学術論文 (審査論文)
| [継承] |
| ○言語 (必須): | □ | 英語
| [継承] |
| ○招待 (推奨): |
| ○審査 (推奨): |
| ○カテゴリ (推奨): |
| ○共著種別 (推奨): |
| ○学究種別 (推奨): |
| ○組織 (推奨): |
| ○著者 (必須): | 1. | 合田 光寛 ([徳島大学.大学院医歯薬学研究部.医学域.先端医学教育研究プロジェクト]/[徳島大学.大学院医歯薬学研究部.医学域.医科学部門.内科系.臨床薬理学])
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 2. | (英) Takatori Shingo (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 3. | (英) Atagi Saori (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 4. | (英) Hashikawa-Hobara Narumi (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| 5. | (英) Kawasaki Hiromu (日) (読)
| ○役割 (任意): |
| ○貢献度 (任意): |
| ○学籍番号 (推奨): |
| [継承] |
| ○題名 (必須): | □ | (英) Nerve growth factor facilitates perivascular innervation in neovasculatures of mice. (日)
| [継承] |
| ○副題 (任意): |
| ○要約 (任意): | □ | (英) It is well known that blood vessels including arterioles have a perivascular innervation. It is also widely accepted that perivascular nerves maintain vascular tone and regulate blood flow. Although there are currently prevailing opinions, unified views on the innervation of microcirculation in any organs have not been established. The present study was designed to investigate whether there are perivascular nerves innervated in microvessels and neovessels. Furthermore, we examined whether nerve growth factor (NGF) can exert a promotional effect on perivascular nerve innervation in neovessels of Matrigel plugs. A Matrigel was subcutaneously implanted in mouse. The presence of perivascular nerves in Matrigel on Day 7-21 after the implantation was immunohistochemically studied. NGF or saline was subcutaneously administered by an osmotic mini-pump for a period of 3-14 days. The immunostaining of neovasculatures in Matrigel showed the presence of perivascular nerves on Day 21 after Matrigel injection. Perivascular nerve innervation of neovessels within Matrigel implanted in NGF-treated mice was observed in Day 17 after Matrigel implantation. However, NGF treatment did not increase numbers of neovessels in Matrigel. These results suggest that perivascular nerves innervate neovessels as neovasculatures mature and that NGF accelerates the innervation of perivascular nerves in neovessels. (日)
| [継承] |
| ○キーワード (推奨): | 1. | (英) Angiogenesis Inducing Agents (日) (読)
| [継承] |
| 2. | (英) Animals (日) (読)
| [継承] |
| 3. | コラーゲン (collagen)
| [継承] |
| 4. | (英) Drug Combinations (日) (読)
| [継承] |
| 5. | (英) Laminin (日) (読)
| [継承] |
| 6. | (英) Male (日) (読)
| [継承] |
| 7. | (英) Mice (日) (読)
| [継承] |
| 8. | (英) Microvessels (日) (読)
| [継承] |
| 9. | (英) Neovascularization, Physiologic (日) (読)
| [継承] |
| 10. | (英) Nerve Growth Factor (日) (読)
| [継承] |
| 11. | (英) Neurogenesis (日) (読)
| [継承] |
| 12. | (英) Proteoglycans (日) (読)
| [継承] |
| ○発行所 (推奨): |
| ○誌名 (必須): | □ | Journal of Pharmacological Sciences ([日本薬理学会])
(pISSN: 1347-8613, eISSN: 1347-8648)
| ○ISSN (任意): | □ | 1347-8648
ISSN: 1347-8613
(pISSN: 1347-8613, eISSN: 1347-8648) Title: Journal of pharmacological sciencesTitle(ISO): J Pharmacol SciSupplier: 公益社団法人 日本薬理学会Publisher: Japanese Pharmacological Society (NLM Catalog)
(医中誌Web)
(J-STAGE)
(Scopus)
(CrossRef)
(Scopus information is found. [need login]) | [継承] |
| [継承] |
| ○巻 (必須): | □ | 131
| [継承] |
| ○号 (必須): | □ | 4
| [継承] |
| ○頁 (必須): | □ | 251 258
| [継承] |
| ○都市 (任意): |
| ○年月日 (必須): | □ | 西暦 2016年 7月 16日 (平成 28年 7月 16日)
| [継承] |
| ○URL (任意): |
| ○DOI (任意): | □ | 10.1016/j.jphs.2016.07.002 (→Scopusで検索)
| [継承] |
| ○PMID (任意): | □ | 27493098 (→Scopusで検索)
| [継承] |
| ○CRID (任意): |
| ○WOS (任意): |
| ○Scopus (任意): |
| ○評価値 (任意): |
| ○被引用数 (任意): |
| ○指導教員 (推奨): |
| ○備考 (任意): | 1. | (英) PublicationType: Journal Article (日)
| [継承] |