○種別 (必須): | □ | 学術論文 (審査論文)
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○言語 (必須): | □ | 英語
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○著者 (必須): | 1. | 岡久 稔也 ([徳島大学.大学院医歯薬学研究部.医学域.連携研究部門(医学域).寄附講座系(医学域).地域総合医療学]/[徳島大学.病院.診療科.内科.消化器内科])
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○学籍番号 (推奨): |
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| 2. | 曽我部 正弘 ([徳島大学.キャンパスライフ健康支援センター])
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| 3. | 中川 忠彦
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| 4. | 田中 久美子
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○学籍番号 (推奨): | □ | ****
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| 5. | 友成 哲
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○学籍番号 (推奨): | □ | ****
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| 6. | 谷口 達哉
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| 7. | 髙橋 章 ([徳島大学.大学院医歯薬学研究部.医学域.栄養科学部門.医科栄養学系.予防環境栄養学])
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| 8. | 木内 陽介
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| 9. | (英) Nishioka Junji (日) 西岡 潤司 (読) にしおか じゅんじ
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○学籍番号 (推奨): | □ | ****
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| 10. | (英) Igata Naoki (日) 井形 直紀 (読) いがた なおき
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○学籍番号 (推奨): | □ | ****
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| 11. | 楊河 宏章
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| 12. | (英) Komatsu takatoshi (日) (読)
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| 13. | (英) Ohnishi Yoshiaki (日) (読)
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| 14. | (英) Fukuhara Masashi (日) (読)
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| 15. | (英) Ishikawa Masashi (日) (読)
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| 16. | 柴田 啓志
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| 17. | (英) Shinomiya Hirohiko (日) (読)
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| 18. | (英) Nakasono Masahiko (日) (読)
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| 19. | (英) Kishi Fumiko (日) (読)
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| 20. | (英) Komai Keiko (日) (読)
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| 21. | (英) Tatsuki Yayoi (日) (読)
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| 22. | (英) Murashima Toru (日) (読)
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| 23. | (英) Deguchi Yoshihiro (日) (読)
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| 24. | (英) Aramaki Hiroshi (日) (読)
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| 25. | (英) Fukumitsu Hideyuki (日) (読)
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| 26. | 高山 哲治 ([徳島大学.大学院医歯薬学研究部.医学域.医科学部門.内科系.消化器内科学])
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○題名 (必須): | □ | (英) Development of a novel automatic ascites filtration and concentration equipment with multi-ring-type roller pump units for cell-free and concentrated ascites reinfusion therapy. (日)
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○要約 (任意): | □ | (英) Cell-free and concentrated ascites reinfusion therapy (CART) is an effective therapy for refractory ascites. However, CART is difficult to perform as ascites filtration and concentration is a complicated procedure. Moreover, the procedure requires the constant assistance of a clinical engineer or/and the use of an expensive equipment for the multi-purpose blood processing. Therefore, we developed a CART specialized equipment (mobility CART [M-CART]) that could be used safely with various safety measures and automatic functions such as automatic washing of clogged filtration filter and self-regulation of the concentration ratio. Downsizing, lightning of the weight, and automatic processing in M-CART required the use of newly developed multi-ring-type roller pump units. This equipment was approved under Japanese regulations in 2018. In performing 41 sessions of CART (for malignant ascites, 22 sessions; and hepatic ascites, 19 sessions) using this equipment in 17 patients, no serious adverse event occurred. An average of 4494 g of ascites was collected and the total amount of ascites was processed in all the sessions without any trouble. The mean weight of the processed ascites was 560 g and the mean concentration ratio was 8.0. The ascites were processed at a flow rate of 50 mL/min. The mean ascites processing time was 112.5 minutes and a 106.5-minutes (95.2%) ascites processing was performed automatically. The operator responded to alarms or support information 3.2 times on average (3.1 minutes, 2.1% of ascites processing time). Human errors related to ascites processing were detected by M-CART at 0.4 times per session on average and were appropriately addressed by the operator. The frequencies of automatic washing of clogged filtration filter and self-regulation of the concentration ratio were 31.7% and 53.7%, respectively. The mean recovery rates (recovery dose) of protein, albumin, and immunoglobulin G were 72.9%, 72.9%, and 71.2% (65.9 g, 34.9 g, and 13.2 g), respectively. Steroids were administered in 92.7% of the sessions to prevent fever and the mean increase in body temperature was 0.53°C. M-CART is a compact and lightweight automatic CART specialized equipment that can safely and easily process a large quantity of ascites without the constant assistance of an operator. (日)
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○キーワード (推奨): |
○発行所 (推奨): |
○誌名 (必須): | □ | Artificial Organs (International Federation for Artificial Organs)
(pISSN: 0160-564X, eISSN: 1525-1594)
○ISSN (任意): | □ | 1525-1594
ISSN: 0160-564X
(pISSN: 0160-564X, eISSN: 1525-1594) Title: Artificial organsTitle(ISO): Artif OrgansSupplier: International Federation for Artificial Organs (IFAO)Publisher: Blackwell (NLM Catalog)
(Wiley)
(Scopus)
(CrossRef)
(Scopus information is found. [need login])
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○巻 (必須): | □ | 44
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○号 (必須): | □ | 8
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○頁 (必須): | □ | 856 872
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○都市 (任意): |
○年月日 (必須): | □ | 西暦 2020年 5月 18日 (令和 2年 5月 18日)
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○URL (任意): |
○DOI (任意): | □ | 10.1111/aor.13681 (→Scopusで検索)
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○PMID (任意): | □ | 32187379 (→Scopusで検索)
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○備考 (任意): | 1. | (英) Article.ELocationID: 10.1111/aor.13681 (日)
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| 2. | (英) Article.PublicationTypeList.PublicationType: Journal Article (日)
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| 3. | (英) KeywordList.Keyword: automatic ascites processing (日)
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| 4. | (英) KeywordList.Keyword: cell-free and concentrated ascites reinfusion therapy (日)
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| 5. | (英) KeywordList.Keyword: refractory ascites (日)
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