『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
ID: Pass:

登録内容 (EID=359323)

EID=359323EID:359323, Map:0, LastModified:2019年9月7日(土) 21:12:03, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[堤 理恵], Read:継承, Write:継承, Delete:継承.
種別 (必須): 学術論文 (審査論文) [継承]
言語 (必須): 英語 [継承]
招待 (推奨):
審査 (推奨):
カテゴリ (推奨):
共著種別 (推奨):
学究種別 (推奨):
組織 (推奨):
著者 (必須): 1. (英) Suresh Padmanaban S (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
2.堤 理恵 ([徳島大学.大学院医歯薬学研究部.医学域.栄養科学部門.医科栄養学系.代謝栄養学])
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
3. (英) Venkatesh Thejaswini (日) (読)
役割 (任意):
貢献度 (任意):
学籍番号 (推奨):
[継承]
題名 (必須): (英) YBX1 at the crossroads of non-coding transcriptome, exosomal, and cytoplasmic granular signaling.  (日)    [継承]
副題 (任意):
要約 (任意): (英) YBX1 (Y box binding protein 1) is an RNA-/DNA-binding multifunctional protein harboring the classical cold shock protein (CSD) domain, an A/P domain, and a long C-terminal domain with alternating positively and negatively charged amino acids. It is a well-established oncogenic transcriptional factor, and regulates apoptosis, translation, cell proliferation, mRNA splicing, repair, differentiation, and stress response. The non-coding transcriptome has added yet another layer of complexity to the YBX1-mediated master regulation of cellular functions. Interestingly, YBX1 has been shown to localize to cytoplasmic granules such as P granules and stress granules. These granules regulate the non-coding transcriptome profile as well as mRNA translation and degradation. In this review, we discuss the recent findings on YBX1 signaling as mediated by various classes of non-coding RNAs, and on the functions of YBX1 at P granules, stress granules, exosomes, and mitochondria. YBX1 is a well-established target for cancer therapy and understanding its functions at organelles and ncRNA transcriptomes will shed new insights for devising organelle based anti-cancer therapies.  (日)    [継承]
キーワード (推奨): 1. (英) Animals (日) (読) [継承]
2. (英) Cytoplasmic Granules (日) (読) [継承]
3. (英) Exosomes (日) (読) [継承]
4. (英) Humans (日) (読) [継承]
5. (英) RNA, Untranslated (日) (読) [継承]
6. (英) Signal Transduction (日) (読) [継承]
7. (英) Transcriptome (日) (読) [継承]
8. (英) Y-Box-Binding Protein 1 (日) (読) [継承]
発行所 (推奨):
誌名 (必須): European Journal of Cell Biology (Deutsche Gesellschaft für Elektronenmikroskopie/Deutsche Gesellschaft für Zellbiologie/European Cell Biology Organization)
(pISSN: 0171-9335, eISSN: 1618-1298)

ISSN (任意): 1618-1298
ISSN: 0171-9335 (pISSN: 0171-9335, eISSN: 1618-1298)
Title: European journal of cell biology
Title(ISO): Eur J Cell Biol
Publisher: Elsevier BV
 (NLM Catalog  (Scopus  (CrossRef (Scopus information is found. [need login])
[継承]
[継承]
(必須): 97 [継承]
(必須): 3 [継承]
(必須): 163 167 [継承]
都市 (任意):
年月日 (必須): 西暦 2018年 2月 19日 (平成 30年 2月 19日) [継承]
URL (任意):
DOI (任意): 10.1016/j.ejcb.2018.02.003    (→Scopusで検索) [継承]
PMID (任意): 29478751    (→Scopusで検索) [継承]
NAID (任意):
WOS (任意):
Scopus (任意):
評価値 (任意):
被引用数 (任意):
指導教員 (推奨):
備考 (任意): 1.(英) PublicationType: Journal Article  (日)    [継承]
2.(英) PublicationType: Review  (日)    [継承]

標準的な表示

和文冊子 ● S Padmanaban Suresh, Rie Tsutsumi and Thejaswini Venkatesh : YBX1 at the crossroads of non-coding transcriptome, exosomal, and cytoplasmic granular signaling., European Journal of Cell Biology, Vol.97, No.3, 163-167, 2018.
欧文冊子 ● S Padmanaban Suresh, Rie Tsutsumi and Thejaswini Venkatesh : YBX1 at the crossroads of non-coding transcriptome, exosomal, and cytoplasmic granular signaling., European Journal of Cell Biology, Vol.97, No.3, 163-167, 2018.

関連情報

Number of session users = 1, LA = 0.55, Max(EID) = 382758, Max(EOID) = 1022288.