『徳島大学 教育・研究者情報データベース (EDB)』---[学外] /
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EID=358790EID:358790, Map:0, LastModified:2020年9月10日(木) 17:22:36, Operator:[大家 隆弘], Avail:TRUE, Censor:0, Owner:[細井 和雄], Read:継承, Write:継承, Delete:継承.
種別 (必須): 総説·解説 [継承]
言語 (必須): 英語 [継承]
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著者 (必須): 1. (英) Kurabuchi Shingo (日) (読)
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2.姚 陳娟 ([徳島大学.大学院医歯薬学研究部.歯学域.口腔科学部門.基礎歯学系.口腔分子生理学])
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3.陳 剛
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4.細井 和雄
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題名 (必須): (英) Reversible Conversion among Subtypes of Salivary Gland Duct Cells as Identified by Production of a Variety of Bioactive Polypeptides  (日)    [継承]
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要約 (任意): (英) Four major kallikreins (mK1, mK22, mK9, and mK13) were identified in the mouse submandibular gland (SMG). mK1, a true tissue kallikrein, was used as a protein marker to identify different types of SMG granular convoluted tubule (GCT) cells along with epidermal growth factor (EGF), nerve growth factor (NGF), and renin. Kallikrein mK1 was localized in a very small number (~5%) of GCT cells, which were scattered throughout the GCT, indicating that the majority of GCT cells are mK1-negative. Among mK1-positive cells, particularly strong signals were observed in a small number of narrow cells, recognized as slender granular cells (SG cells, Type IV), in the GCT. After postnatal development of the SMG, GCT cells are no longer uniform based on the bioactive substances (mK1, EGF, NGF, and renin) that they produce and secrete. GCT cells were classified into four subtypes, Types I-IV, and it became clear that these subtypes are complicatedly and reversibly converted by the endocrine hormones 5α-dihydrotestosterone (DHT) and triiodothyronine (T). Duct segments with similar morphology or hormone dependency were recognized in the sublingual and parotid glands. The presence of duct cells with such characteristics is therefore a common feature of the three major salivary glands of rodents.  (日)    [継承]
キーワード (推奨): 1. (英) 5α-dihydrotestosterone (日) (読) [継承]
2. (英) epidermal growth factor (日) (読) [継承]
3. (英) granular convoluted tubular cells (日) (読) [継承]
4. (英) mK1 (日) (読) [継承]
5. (英) submandibular gland (日) (読) [継承]
発行所 (推奨):
誌名 (必須): Acta Histochemica et Cytochemica (日本組織細胞化学会)
(pISSN: 0044-5991, eISSN: 1347-5800)

ISSN (任意): 0044-5991
ISSN: 0044-5991 (pISSN: 0044-5991, eISSN: 1347-5800)
Title: Acta histochemica et cytochemica
Title(ISO): Acta Histochem Cytochem
Supplier: 日本組織細胞化学会
Publisher: Japan Society of Histochemistry and Cytochemistry
 (NLM Catalog  (Webcat Plus  (医中誌Web  (J-STAGE  (Scopus  (CrossRef (Scopus information is found. [need login])
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年月日 (必須): 西暦 2019年 8月 27日 (令和 元年 8月 27日) [継承]
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DOI (任意): 10.1267/ahc.19014    (→Scopusで検索) [継承]
PMID (任意): 31602049    (→Scopusで検索) [継承]
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備考 (任意): 1.(英) Article.ELocationID: 10.1267/ahc.19014  (日)    [継承]
2.(英) Article.PublicationTypeList.PublicationType: Journal Article  (日)    [継承]
3.(英) Article.PublicationTypeList.PublicationType: Review  (日)    [継承]
4.(英) KeywordList.Keyword: 5α-dihydrotestosterone  (日)    [継承]
5.(英) KeywordList.Keyword: epidermal growth factor  (日)    [継承]
6.(英) KeywordList.Keyword: granular convoluted tubular cells  (日)    [継承]
7.(英) KeywordList.Keyword: mK1  (日)    [継承]
8.(英) KeywordList.Keyword: submandibular gland  (日)    [継承]
9.(英) CoiStatement: IXThere are no conflicts of interest to declare.  (日)    [継承]

標準的な表示

和文冊子 ● Shingo Kurabuchi, Chenjuan Yao, Gang Chen and Kazuo Hosoi : Reversible Conversion among Subtypes of Salivary Gland Duct Cells as Identified by Production of a Variety of Bioactive Polypeptides, Acta Histochemica et Cytochemica, Vol.52, No.4, 59-65, Aug. 2019.
欧文冊子 ● Shingo Kurabuchi, Chenjuan Yao, Gang Chen and Kazuo Hosoi : Reversible Conversion among Subtypes of Salivary Gland Duct Cells as Identified by Production of a Variety of Bioactive Polypeptides, Acta Histochemica et Cytochemica, Vol.52, No.4, 59-65, Aug. 2019.

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